Evidence ofmdx mouse skeletal muscle fragility in vivo by eccentric running exercise

Dystrophin: The protein product of the duchenne muscular dystrophy locus

1987 • 4,477 citations

X chromosome-linked muscular dystrophy (mdx) in the mouse.

1984 • 1,678 citations

Dystrophin protects the sarcolemma from stresses developed during muscle contraction.

1993 • 1,444 citations

Membrane organization of the dystrophin-glycoprotein complex

1991 • 1,321 citations

The Molecular Basis of Muscular Dystrophy in the mdx Mouse: a Point Mutation

1989 • 1,171 citations

The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

1991 • 892 citations

Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts

1989 • 856 citations

Three muscular dystrophies: Loss of cytoskeleton-extracellular matrix linkage

1995 • 829 citations

Eccentric exercise-induced injury to rat skeletal muscle

1983 • 783 citations

Immunoelectron microscopic localization of dystrophin in myofibres

1988 • 447 citations

Disruptions of muscle fiber plasma membranes. Role in exercise-induced damage.

1992 • 431 citations

Growth factors are released by mechanically wounded endothelial cells.

1989 • 420 citations

Calcium entry through stretch-inactivated ion channels in mdx myotubes

1990 • 394 citations

mdx mice show progressive weakness and muscle deterioration with age

1995 • 383 citations

Visualization of Dystrophic Muscle Fibers in Mdx Mouse by Vital Staining with Evans Blue: Evidence of Apoptosis in Dystrophin-Deficient Muscle

1995 • 355 citations

Increased Activity of Calcium Leak Channels in Myotubes of Duchenne Human and mdx Mouse Origin

1990 • 353 citations

Increased susceptibility of EDL muscles from mdx mice to damage induced by contractions with stretch

1993 • 319 citations

Mechanical function of dystrophin in muscle cells.

1995 • 284 citations

Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity

1993 • 281 citations

Somatic reversion/suppression of the mouse mdx phenotype in vivo

1990 • 273 citations

Normal myogenic cells from newborn mice restore normal histology to degenerating muscles of the mdx mouse.

1990 • 241 citations

Healing of skeletal muscle injury

1991 • 223 citations

Dystrophin-deficient mdx muscle fibers are preferentially vulnerable to necrosis induced by experimental lengthening contractions

1990 • 221 citations

Long–term correction of mouse dystrophic degeneration by adenovirus–mediated transfer of a minidystrophin gene

1993 • 201 citations

Fiber regeneration is not persistent in dystrophic (mdx) mouse skeletal muscle

1991 • 200 citations

Very efficient myoblast allotransplantation in mice under FK506 immunosuppression

1994 • 198 citations

Phenotype of dystrophinopathy in old MDX mice

1995 • 191 citations

Plasma creatine kinase changes after eccentric and concentric contractions

1986 • 174 citations

Lesions in the rat soleus muscle following eccentrically biased exercise

1988 • 144 citations

Abnormalities in structure and function of limb skeletal muscle fibres of dystrophic mdx mice

1992 • 136 citations

Functional protection of dystrophic mouse (mdx) muscles after adenovirus-mediated transfer of a dystrophin minigene.

1996 • 126 citations

Canine X‐linked muscular dystrophy as an animal model of Duchenne muscular dystrophy: A review

1992 • 125 citations

Contractile properties and susceptibility to exercise-induced damage of normal and mdx mouse tibialis anterior muscle

1992 • 116 citations

Influence of dystrophin-gene mutation onmdx mouse behavior. I. Retention deficits at long delays in spontaneous alternation and bar-pressing tasks

1995 • 95 citations

Morphometric analysis of mdx diaphragm muscle fibres. Comparison with hindlimb muscles

1993 • 89 citations

Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin.

1995 • 88 citations

Age‐related differences in regeneration of dystrophic (mdx) and normal muscle in the mouse

1995 • 87 citations

How does dystrophin deficiency lead to muscle degeneration? — Evidence from the MDX mouse

1995 • 86 citations

Muscle injury, cross‐sectional area and fibre type distribution in mouse soleus after intermittent wheel‐running.

1990 • 84 citations

Dystrophin-deficient myofibers are vulnerable to mast cell granule-induced necrosis

1994 • 77 citations

Complex fiber-type-specific expression of fast skeletal muscle troponin I gene constructs in transgenic mice

1993 • 71 citations

A noninvasive procedure to detect muscle weakness in the mdx mouse

1990 • 70 citations

The effects of endurance exercise on dystrophic mdx mice. I. Contractile and histochemical properties of intact muscles

1993 • 68 citations

ROLE OF MECHANICAL DAMAGE IN PATHOGENESIS OF PROXIMAL MYOPATHY IN MAN

1984 • 60 citations

Further aspects of muscular dystrophy in mdx mice

1993 • 54 citations

Problems and paradigms: Dystrophin as a mechanochemical transducer in skeletal muscle

1993 • 43 citations

Progressive deterioration of muscles in mdx mice induced by overload

1993 • 31 citations

The effect of exercise on canine dystrophic muscle

1989 • 21 citations

Effects of Treadmill Exercise and High-Fat Feeding on Muscle Degeneration in Mdx Mice at the time of Weaning

1995 • 16 citations

An injury model myopathy mimicking dystrophy: Implications regarding the function of dystrophin

1991 • 9 citations