The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol.

THE ENVELOPE OF MYCOBACTERIA

1995 • 1,868 citations

Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

1990 • 1,231 citations

Modular Organization of Genes Required for Complex Polyketide Biosynthesis

1991 • 883 citations

Cholera toxin transcriptional activator ToxR is a transmembrane DNA binding protein

1987 • 626 citations

Antimicrobial agent resistance in mycobacteria: molecular genetic insights

1995 • 601 citations

[25] Genetic systems for mycobacteria

1991 • 437 citations

The use of transposon Tn5 mutagenesis in the rapid generation of correlated physical and genetic maps of DNA segments cloned into multicopy plasmids — a review

1984 • 422 citations

Site-specific integration of mycobacteriophage L5: integration-proficient vectors for Mycobacterium smegmatis, Mycobacterium tuberculosis, and bacille Calmette-Guérin.

1991 • 397 citations

The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of streptomyces

1991 • 357 citations

The current status and portability of our sequence handling software

1986 • 357 citations

Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis

1989 • 350 citations

Biogenesis of the mycobacterial cell wall and the site of action of ethambutol

1995 • 286 citations

Recognition of the lipid intermediate for arabinogalactan/arabinomannan biosynthesis and its relation to the mode of action of ethambutol on mycobacteria.

1994 • 267 citations

Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.

1992 • 229 citations

Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.

1989 • 226 citations

OVERLAPPING GENES

1983 • 225 citations

DNA sequence, structure and gene expression of mycobacteriophage L5: a phage system for mycobacterial genetics

1993 • 223 citations

Divergent promoters, a common form of gene organization

1988 • 195 citations

Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius

1992 • 167 citations

Superinfection immunity of mycobacteriophage L5: applications for genetic transformation of mycobacteria

1993 • 161 citations

Drug Susceptibility in the Chemotherapy of Mycobacterial Infections

1991 • 150 citations

Nucleotide sequence and transcriptional analysis of the redD locus of Streptomyces coelicolor A3(2)

1990 • 147 citations

MOLECULAR BIOLOGY OF THE MYCOBACTERIA

1989 • 145 citations

Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2)

1990 • 137 citations

Drug susceptibility in the chemotherapy of mycobacterial infections

1992 • 131 citations

A new synthetic compound with antituberculous activity in mice: ethambutol (dextro-2,2'-(ethylenediimino)-di-l-butanol).

1961 • 87 citations

Rough morphological variants of Mycobacterium avium. Characterization of genomic deletions resulting in the loss of glycopeptidolipid expression

1993 • 81 citations

In vivo repackaging of recombinant cosmid molecules for analyses of Salmonella typhimurium, Streptococcus mutans, and mycobacterial genomic libraries

1986 • 68 citations

Molecular biology of the mycobacteria

1990 • 64 citations

Rapid mycobacterial plasmid analysis by electroduction between Mycobacterium spp. and Escherichia coli

1992 • 61 citations

Loci of Mycobacterium avium ser2 gene cluster and their functions

1994 • 29 citations

Molecular-genetic evidence for the relationship of Mycobacterium leprae to slow-growing pathogenic mycobacteria.

1988 • 25 citations