Specific Activation of LIM kinase 2 via Phosphorylation of Threonine 505 by ROCK, a Rho-dependent Protein Kinase

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1997 • 2,847 citations

Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

1999 • 1,581 citations

Actin-Based Cell Motility and Cell Locomotion

1996 • 1,536 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

1998 • 1,384 citations

Active and Inactive Protein Kinases: Structural Basis for Regulation

1996 • 1,361 citations

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

1998 • 1,263 citations

Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

1997 • 1,085 citations

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

1999 • 1,048 citations

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

1996 • 1,045 citations

Regulation of the Cytoskeleton and Cell Adhesion by the Rho Family GTPases in Mammalian Cells

1999 • 1,015 citations

Proteins of the ADF/Cofilin Family: Essential Regulators of Actin Dynamics

1999 • 1,004 citations

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

1996 • 872 citations

The p160 RhoA-Binding Kinase ROKα Is a Member of a Kinase Family and Is Involved in the Reorganization of the Cytoskeleton

1996 • 866 citations

A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes

1995 • 711 citations

Phosphorylation of Myosin-Binding Subunit (Mbs) of Myosin Phosphatase by Rho-Kinase in Vivo

1999 • 559 citations

p160^ROCK, a Rho‐associated coiled‐coil forming protein kinase, works downstream of Rho and induces focal adhesions

1997 • 510 citations

Rho-associated Kinase ROCK Activates LIM-kinase 1 by Phosphorylation at Threonine 508 within the Activation Loop

2000 • 507 citations

SIGNALING TO THE ACTIN CYTOSKELETON

1998 • 450 citations

Phosphorylation of Ser‐3 of cofilin regulates its essential function on actin

1996 • 396 citations

Rho as a regulator of the cytoskeleton

1995 • 386 citations

Cofilin Phosphorylation and Actin Cytoskeletal Dynamics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2

1999 • 384 citations

Putting a new twist on actin: ADF/cofilins modulate actin dynamics

1999 • 371 citations

Reactivation of Phosphorylated Actin Depolymerizing Factor and Identification of the Regulatory Site

1995 • 369 citations

PLECKSTRIN HOMOLOGY DOMAINS: A Common Fold with Diverse Functions

1998 • 289 citations

Specific Localization of Serine 19 Phosphorylated Myosin II during Cell Locomotion and Mitosis of Cultured Cells

1998 • 231 citations

Phosphorylation of Vimentin by Rho-associated Kinase at a Unique Amino-terminal Site That Is Specifically Phosphorylated during Cytokinesis

1998 • 222 citations

Control of Actin Assembly at Filament Ends

1995 • 202 citations

Identification and Characterization of a Novel Family of Serine/Threonine Kinases Containing Two N-terminal LIM Motifs

1995 • 195 citations

In vivo functions of actin-binding proteins

1998 • 194 citations

Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows.

1995 • 192 citations

Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif.

1994 • 182 citations

Roles of Rho-associated Kinase in Cytokinesis; Mutations in Rho-associated Kinase Phosphorylation Sites Impair Cytokinetic Segregation of Glial Filaments

1998 • 164 citations

Radixin, a barbed end-capping actin-modulating protein, is concentrated at the cleavage furrow during cytokinesis [published erratum appears in J Cell Biol 1991 Sep;114(5):1101-3]

1991 • 147 citations

Phosphorylation of Glial Fibrillary Acidic Protein at the Same Sites by Cleavage Furrow Kinase and Rho-associated Kinase

1997 • 131 citations

Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments

1999 • 116 citations

Structural Features of LIM Kinase That Control Effects on the Actin Cytoskeleton

1999 • 96 citations

Kiz-1, a protein with LIM zinc finger and kinase domains, is expressed mainly in neurons.

1994 • 92 citations

Balance between Activities of Rho Kinase and Type 1 Protein Phosphatase Modulates Turnover of Phosphorylation and Dynamics of Desmin/Vimentin Filaments

1999 • 91 citations

LIMK-1 and LIMK-2, two members of a LIM motif-containing protein kinase family.

1995 • 86 citations

Comparison of tissue distribution of two novel serine/threonine kinase genes containing the LIM motif (LIMK-1 and LIMK-2) in the developing rat

1997 • 56 citations

Mouse LIM-Kinase 2 Gene: cDNA Cloning, Genomic Organization, and Tissue-Specific Expression of Two Alternatively Initiated Transcripts

1997 • 43 citations

Molecular Cloning of a Chicken Lung cDNA Encoding a Novel Protein Kinase with N-Terminal Two LIM/Double Zinc Finger Motifs1

1994 • 42 citations

A Novel Transcript Encoding Truncated LIM Kinase 2 Is Specifically Expressed in Male Germ Cells Undergoing Meiosis

1998 • 28 citations

cDNA Cloning, Genomic Organization, and Chromosomal Localization of the Mouse LIM Motif-Containing Kinase Gene, Limk2

1997 • 23 citations