Preheat Treatment for Mycobacterium tuberculosis Hsp16.3: Correlation between a Structural Phase Change at 60°C and a Dramatic Increase in Chaperone-like Activity

The Biology of heat shock proteins and molecular chaperones.

1994 • 1,226 citations

The biology of heat shock proteins and molecular chaperones

1994 • 1,203 citations

Crystal structure of a small heat-shock protein

1998 • 876 citations

Genealogy of the α-crystallin—small heat-shock protein superfamily

1998 • 480 citations

Mycobacterial Stationary Phase Induced by Low Oxygen Tension: Cell Wall Thickening and Localization of the 16-Kilodalton α-Crystallin Homolog

1998 • 352 citations

The expanding small heat-shock protein family, and structure predictions of the conserved “α-crystallin domain”

1995 • 348 citations

Stationary phase-associated protein expression in Mycobacterium tuberculosis: function of the mycobacterial alpha-crystallin homolog

1996 • 316 citations

The 16-kDa α-crystallin (Acr) protein ofMycobacterium tuberculosisis required for growth in macrophages

1998 • 315 citations

Mycobacterium tuberculosis 16-kDa Antigen (Hsp16.3) Functions as an Oligomeric Structure in Vitro to Suppress Thermal Aggregation

1996 • 230 citations

Characterization of the major membrane protein of virulent Mycobacterium tuberculosis

1992 • 176 citations

Results of a World Health Organization-sponsored workshop to characterize antigens recognized by mycobacterium-specific monoclonal antibodies

1986 • 150 citations

Micellar subunit assembly in a three-layer model of oligomeric alpha-crystallin.

1991 • 133 citations

The 14,000-molecular-weight antigen of Mycobacterium tuberculosis is related to the alpha-crystallin family of low-molecular-weight heat shock proteins

1992 • 132 citations

On the thermal stability of .alpha.-crystallin: z new insight from infrared spectroscopy

1995 • 97 citations

Heat‐induced changes in the conformation of α‐ and β‐crystalline: Unique thermal stability of α‐crystallin

1988 • 95 citations

Molecular chaperones in the life cycle of proteins : structure, function, and mode of action

1998 • 77 citations

The mycobacterium tuberculosis small heat shock protein Hsp16.3 exposes hydrophobic surfaces at mild conditions: Conformational flexibility and molecular chaperone activity

1999 • 75 citations

Chaperone-like Activity of Tubulin

1998 • 73 citations

Correlation between the Chaperone-like Activity and Aggregate Size of α-Crystallin with Increasing Temperature

2000 • 38 citations

Effect of Heat-Induced Structural Perturbation of Secondary and Tertiary Structures on the Chaperone Activity of α-Crystallin

1997 • 38 citations

Physiological Role of the Association Complexes of α-Crystallin and Its Substrates on the Chaperone Activity

1998 • 31 citations

α- C-terminal domain: on the track of an Ig fold

1998 • 29 citations

Electrostatic interactions play a critical role in Mycobacterium tuberculosis Hsp16.3 binding of substrate proteins.

2001 • 8 citations