Interaction between serine β-lactamases and class a substrates: A kinetic analysis and a reaction pathway hypothesis

Kinetic studies on the inactivation of Escherichia coli RTEM β-lactamase by clavulanic acid

1978 • 204 citations

Enzyme Inhibitors as Drugs

1980 • 190 citations

Kinetic Evidence for the Formation of Acyl-Enzyme Intermediates in the α-Chymotrypsin-Catalyzed Hydrolyses of Specific Substrates

1964 • 174 citations

Zinc as a Cofactor for Cephalosporinase from Bacillus cereus 569

1966 • 144 citations

A membrane enzyme from Staphylococcus aureus which catalyzes transpeptidase, carboxypeptidase, and penicillinase activities

1978 • 136 citations

Penicillinase active sites: Labelling of serine‐44 in β‐lactamase I by 6β‐bromopenicillanic acid

1979 • 129 citations

Occurrence of a serine residue in the penicillin‐binding site of the exocellular DD‐carboxy‐peptidase‐transpeptidase from Streptomyces R61

1976 • 108 citations

Kinetics of Interaction between the Exocellular DD‐Carboxypeptidase‐Transpeptidase from Streptomyces R61 and β‐Lactam Antibiotics

1975 • 84 citations

Fragmentation of benzylpenicillin after interaction with the exocellular DD-carboxypeptidase-transpeptidases of Streptomyces R61 and R39

1975 • 78 citations

Mode of interaction between β-lactam antibiotics and the exocellular DD-carboxypeptidase–transpeptidase from Streptomyces R39.

1976 • 50 citations

Fate of thiazolidine ring during fragmentation of penicillin by exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61

1976 • 49 citations

Chromatin structure and specificity revealed by immunological techniques

1976 • 32 citations

[53f] β-Lactamases (Actinomycetes species)

1975 • 31 citations

‘β-Lactams’ as β-lactamase inhibitors

1980 • 28 citations

The interaction of penicillinase with penicillins

1968 • 26 citations

The interaction of penicillinase with penicillins

1968 • 25 citations

Reversible inhibition of penicillinase by quinacillin: Evaluation of mechanisms involving two conformational states of the enzyme

1978 • 23 citations

The penicillin-binding site in the exocellular <scp>dd</scp>-carboxypeptidase-transpeptidase of Actinomadura R39

1981 • 21 citations

Active sites of β-lactamases from Bacillus cereus

1980 • 21 citations

NMR evidence for the structure of the complex between penicillin and the DD‐carboxypeptidase of streptomyces R61

1979 • 14 citations

THE COEFFICIENT OF SAPONIFICATION OF ETHYL ACETATE BY SODIUM HYDROXIDE

1927 • 12 citations

Relative Substituent Effects on Alkaline Solvolysis of β-Lactams (2-Azetidinones) and Amides

1971 • 11 citations

INACTIVATION OF STAPHYLOCOCCAL PENICILLINASE BY DICLOXACILLIN

1973 • 8 citations

Inactivation of Bacillus cereus beta-Lactamase by Halogenated Isoxazolylpenicillins

1976 • 7 citations