A segment-based approach to protein secondary structure prediction

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Comparison of the predicted and observed secondary structure of T4 phage lysozyme

1975 • 4,853 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

A new force field for molecular mechanical simulation of nucleic acids and proteins

1984 • 4,553 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins

1974 • 2,173 citations

Dynamics of folded proteins

1977 • 1,929 citations

Amino Acid Preferences for Specific Locations at the Ends of α Helices

1988 • 1,356 citations

Structural patterns in globular proteins

1976 • 1,286 citations

Predicting the secondary structure of globular proteins using neural network models

1988 • 1,243 citations

Computer simulation of protein folding

1975 • 1,020 citations

Structure of calmodulin refined at 2.2 Å resolution

1988 • 1,019 citations

The MIDAS display system

1988 • 955 citations

Protein secondary structure and circular dichroism: A practical guide

1990 • 926 citations

Comparison of super-secondary structures in proteins

1973 • 885 citations

Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR

1988 • 823 citations

The crystal structure of human deoxyhaemoglobin at 1.74 Å resolution

1984 • 738 citations

Crystal structure of yeast cytochrome c peroxidase refined at 1.7-A resolution.

1984 • 714 citations

Improvements in protein secondary structure prediction by an enhanced neural network

1990 • 708 citations

Structural Characterization of a Partly Folded Apomyoglobin Intermediate

1990 • 708 citations

Evidence for a molten globule state as a general intermediate in protein folding

1990 • 677 citations

NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

1988 • 583 citations

Further developments of protein secondary structure prediction using information theory

1987 • 573 citations

Protein secondary structure prediction with a neural network.

1989 • 506 citations

The Internal Dynamics of Globular Protein

1981 • 505 citations

Crystallographic refinement and atomic models of two different forms of citrate synthase at 2·7 and 1·7 Å resolution

1982 • 495 citations

Algorithms for prediction of α-helical and β-structural regions in globular proteins

1974 • 465 citations

Neutron diffraction reveals oxygen–histidine hydrogen bond in oxymyoglobin

1981 • 449 citations

Refinement of the structure of carp muscle calcium-binding parvalbumin by model building and difference fourier analysis

1975 • 433 citations

Visualization of protein-nucleic acid interactions in a virus

1989 • 430 citations

Identification of structural motifs from protein coordinate data: Secondary structure and first‐level supersecondary structure*

1988 • 409 citations

On the use of sequence homologies to predict protein structure: identical pentapeptides can have completely different conformations.

1984 • 386 citations

Packing of α-helices: Geometrical constraints and contact areas

1978 • 366 citations

Capping and α-helix stability

1989 • 363 citations

Structural principles of the globular organization of protein chains. A stereochemical theory of globular protein secondary structure

1974 • 355 citations

Structure of bacteriophage T4 lysozyme refined at 1.7 Å resolution

1987 • 349 citations

An algorithm for protein secondary structure prediction based on class prediction

1987 • 348 citations

The refined structure of vitamin D-dependent calcium-binding protein from bovine intestine. Molecular details, ion binding, and implications for the structure of other calcium-binding proteins.

1986 • 340 citations

Simulations of the Folding of a Globular Protein

1990 • 322 citations

Hydrophobic Organization of Membrane Proteins

1989 • 316 citations

Structure of erythrocruorin in different ligand states refined at 1·4 Å resolution

1979 • 304 citations

Automatic generation of primary sequence patterns from sets of related protein sequences.

1990 • 292 citations

Determination of protein secondary structure using factor analysis of infrared spectra

1990 • 260 citations

Turn prediction in proteins using a pattern-matching approach

1986 • 212 citations

Topological distribution of four-alpha-helix bundles.

1989 • 189 citations

Prediction of protein structural class from the amino acid sequence

1986 • 173 citations

Logical analysis of the mechanism of protein folding

1973 • 167 citations

Structure of ferricytochrome c′ from Rhodospirillum molischianum at 1.67 Å resolution

1985 • 166 citations

Phase diagram for acidic conformational states of apomyoglobin

1990 • 156 citations

Protein folding: Evaluation of some simple rules for the assembly of helices into tertiary structures with myoglobin as an example

1979 • 155 citations

A sequence motif in the transmembrane region of growth factor receptors with tyrosine kinase activity mediates dimerization

1990 • 146 citations

Analysis and prediction of the packing of α-helices against a β-sheet in the tertiary structure of globular proteins

1982 • 141 citations

Improvement of the 2.5 Å resolution model of cytochrome b562 by redetermining the primary structure and using molecular graphics

1981 • 139 citations

Flexibility of the DNA‐binding domains of trp repressor

1988 • 133 citations

Structure of human foetal deoxyhaemoglobin

1977 • 132 citations

Structure of rice ferricytochrome c at 2·0 Å resolution

1983 • 131 citations

Describing protein structure: A general algorithm yielding complete helicoidal parameters and a unique overall axis

1989 • 127 citations

Improvements in a secondary structure prediction method based on a search for local sequence homologies and its use as a model building tool

1988 • 119 citations

Analysis and prediction of protein β-sheet structures by a combinatorial approach

1980 • 105 citations

Identification of protein folds: Matching hydrophobicity patterns of sequence sets with solvent accessibility patterns of known structures

1990 • 99 citations

Computer Simulations of Globular Protein Folding and Tertiary Structure

1989 • 97 citations

Amino acid sequence homology applied to the prediction of protein secondary structures, and joint prediction with existing methods

1986 • 95 citations

A Critical Evaluation of Methods for Prediction of Protein Secondary Structures

1988 • 94 citations

Logical analysis of the mechanism of protein folding

1974 • 82 citations

Refinement of a molecular model for lamprey hemoglobin from Petromyzon marinus

1985 • 78 citations

Crystal structure of Azotobacter cytochrome c5 at 2.5 Å resolution

1985 • 63 citations

Adjustment of restraints in the refinement of methemerythrin and azidomethemerythrin at 2.0 Å resolution

1983 • 47 citations

Amino acid composition and hydrophobicity patterns of protein domains correlate with their structures

1985 • 43 citations

Monte Carlo simulation of equilibrium globular protein folding: alpha-helical bundles with long loops.

1989 • 42 citations

Correlation of Amino Acid Sequence and Conformation in Tobacco Mosaic Virus

1968 • 25 citations