Thyroid follicular cell carcinogenesis*1

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

Growth Factors and Cancer

1991 • 2,044 citations

The Thyroid Gland.

1965 • 1,816 citations

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1985 • 1,782 citations

Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

1982 • 1,559 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

1982 • 1,424 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Dual control of cell growth by somatomedins and platelet-derived growth factor.

1979 • 926 citations

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion.

1976 • 850 citations

Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals

1986 • 771 citations

The Action of Oncogenes in the Cytoplasm and Nucleus

1985 • 708 citations

GROSS AND MICROSCOPIC FINDINGS IN CLINICALLY NORMAL THYROID GLANDS*

1955 • 703 citations

Cellular Localization of Somatomedin (Insulin-Like Growth Factor) Messenger RNA in the Human Fetus

1987 • 663 citations

Multiplicity of mammalian microsomal cytochromes P-45.

1979 • 633 citations

Mechanisms of Tumor Progression

2010 • 608 citations

Endogenous hormones as a major factor in human cancer.

1982 • 599 citations

Thyroid Hormone Action at the Cellular Level

1979 • 502 citations

Nodular Thyroid Disease

1985 • 484 citations

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

1986 • 441 citations

Further mutagenicity studies on pesticides in bacterial reversion assay systems

1983 • 399 citations

Malignant and Benign Neoplasms of the Thyroid in Patients Treated for Hyperthyroidism: A Report of the Cooperative Thyrotoxicosis Therapy Follow-up Study

1974 • 389 citations

Environmental Iodine Intake and Thyroid Dysfunction During Chronic Amiodarone Therapy

1984 • 376 citations

A Population-Based Case-Control Study of Thyroid Cancer

1987 • 353 citations

Thyroid-Pituitary Interaction

1982 • 351 citations

Replacement Dose, Metabolism, and Bioavailability of Levothyroxine in the Treatment of Hypothyroidism

1987 • 350 citations

Differential Expression of the Translocated and the Untranslocated c- myc Oncogene in Burkitt Lymphoma

1983 • 328 citations

Use of Historical Control Data in Carcinogenicity Studies in Rodents

1984 • 319 citations

Chemical mutagenesis testing in drosophila. IV. Results of 45 coded compounds tested for the national toxicology program

1985 • 318 citations

Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells

1982 • 318 citations

The Toxicity of Polychlorinated Polycyclic Compounds and Related Chemicals

1973 • 310 citations

Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene.

1974 • 293 citations

INSULIN-LIKE GROWTH FACTOR-I STIMULATES THE GROWTH OF RAT THYROID CELLS IN CULTURE AND SYNERGIZES THE STIMULATION OF DNA SYNTHESIS INDUCED BY TSH AND GRAVES′-IgG

1986 • 286 citations

Cancer Statistics, 1988

1988 • 282 citations

Participation of c- myc Protein in DNA Synthesis of Human Cells

1986 • 282 citations

Polychlorinated Biphenyls: A New Type of Inducer of Cytochrome P-448 in the Liver

1973 • 273 citations

EFFECT OF SULFONAMIDES AND THIOUREAS ON THE THYROID GLAND AND BASAL METABOLISM¹²

1943 • 272 citations

Differential expression of the normal and of the translocated human c-myc oncogenes in B cells.

1983 • 262 citations

The Mechanism of Action of the Thioureylene Antithyroid Drugs

1976 • 245 citations

Transcriptional regulation of the thyrotropin subunit genes by thyroid hormone.

1985 • 245 citations

Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.

1986 • 241 citations

Thyroid cancer in an iodide rich area. A histopathological study

1977 • 240 citations

Suppressive Therapy with Levothyroxine for Solitary Thyroid Nodules

1987 • 230 citations

Cell transformation by chemical agents — A review and analysis of the literature

1983 • 224 citations

ACTION OF CERTAIN SULFONAMIDES AND OF THIOUREA UPON THE FUNCTION OF THE THYROID GLAND OF THE RAT¹

1943 • 219 citations

Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

1984 • 219 citations

A Common Mechanism of Chromosomal Translocation in T- and B-Cell Neoplasia

1986 • 205 citations

Enhanced Thyroxine Metabolism and High Uptake Goiters in Rats After a Single Dose of 2,3,7,8- Tetrachlorodibenzo-p-Dioxin1¹

1977 • 201 citations

Deregulation of c- myc by Translocation of the α-Locus of the T-Cell Receptor in T-Cell Leukemias

1986 • 199 citations

Evaluation of the Mutagenicity and DNA-Modifying Activity of Carcinogens and Noncarcinogens in Microbial Systems<xref ref-type="fn" rid="FN2">2</xref>

1979 • 195 citations

Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.

1975 • 188 citations

Factors controlling proliferation and differentiation of canine thyroid cells cultured in reduced serum conditions: effects of thyrotropin, cyclic AMP and growth factors

1984 • 186 citations

Spectrum of Pituitary Alteration with Mild and Severe Thyroid Impairment* †

1978 • 186 citations

Occult thyroid carcinoma in olmsted county, minnesota: Prevalence at autopsy compared with that in hiroshima and nagasaki. Japan

1974 • 185 citations

Antibodies That Promote Thyroid Growth

1983 • 181 citations

The Role of Thyroid-Stimulating Antibodies of Graves' Disease in Differentiated Thyroid Cancer

1988 • 172 citations

Epidermal Growth Factor Modulates Thyroid Growth and Function in Culture*

1983 • 170 citations

Induction of thyroid tumors in rats by a low iodine diet

1955 • 169 citations

STRUMA LYMPHOMATOSA (HASHIMOTO'S THYROIDITIS) AND RELATED THYROIDAL DISORDERS*

1959 • 169 citations

Thyroid and antithyroid drugs

1983 • 165 citations

Increased thyroxine turnover and thyroidal function after stimulation of hepatocellular binding of thyroxine by phenobarbital

1968 • 161 citations

Hypothyroidism and Abnormalities in the Kinetics of Thyroid Hormone Metabolism in Rats Treated Chronically with Polychlorinated Biphenyl and Polybrominated Biphenyl*

1987 • 159 citations

Hypothyroidism in Workers Exposed to Polybrominated Biphenyls

1980 • 156 citations

Testing of twenty-one environmental aromatic amines or derivatives for long-term toxicity or carcinogenicity.

1978 • 153 citations

The Effect of Sulfanilylguanidine on the Thyroid of the Rat

1941 • 144 citations

Phorbol Esters Stimulate Growth and Inhibit Differentiation in Cultured Thyroid Cells*

1985 • 142 citations

Thyroid cancer among young women related to prior thyroid disease and pregnancy history

1987 • 140 citations

Thyrotropin and dibutyryl cyclic AMP increase levels of c-myc and c-fos mRNAs in cultured rat thyroid cells.

1986 • 140 citations

Incidence of thyroid carcinoma in Graves' disease

1970 • 139 citations

Reduction in extrathyroidal triiodothyronine production by propylthiouracil in man.

1975 • 138 citations

FURTHER STUDIES ON THE CHEMICAL NATURE OF COMPOUNDS WHICH INHIBIT THE FUNCTION OF THE THYROID GLAND¹¹

1945 • 137 citations

The Irreversible Inactivation of Thyroid Peroxidase by Methylmercaptoimidazole, Thiouracil, and Propylthiouracil in Vitro and Its Relationship to in Vivo Findings*

1978 • 136 citations

Appendix II. The bacterial mutation test

1978 • 136 citations

Do induced sperm-head abnormalities in mice specifically identify mammalian mutagens rather than carcinogens?

1980 • 136 citations

Effects of a Polychlorinated Biphenyl Mixture (Aroclor 1254) and DDT on Biliary Thyroxine Excretion in Rats¹

1974 • 134 citations

The rat as model for the study of drug effects on thyroid function: Consideration of methodological problems

1979 • 127 citations

Oncogenes and human cancer: cause or consequence?

1986 • 127 citations

Thyroid Neoplasia in Marshall Islanders Exposed to Nuclear Fallout

1987 • 120 citations

Chromosome translocations and human cancer.

1986 • 120 citations

The Effect of Radioactive Iodine alone and in Combination with Methylthiouracil upon Tumour Production in the Rat's Thyroid Gland

1953 • 116 citations

Endocrine and Morphologic Studies of Pituitary Adenomas Secondary to Primary Hypothyroidism

1977 • 116 citations

DETERMINATION OF THE RELATIVE ACTIVITIES OF ANTITHYROID COMPOUNDS IN MAN USING RADIOACTIVE IODINE¹

1947 • 115 citations

Chemical Induction of Cancer: Structural Bases and Biological Mechanisms

2013 • 115 citations

Toxicology of octabromobiphenyl and decabromodiphenyl oxide.

1975 • 114 citations

Induction of the c- fos Oncogene by Thyrotropic Hormone in Rat Thyroid Cells in Culture

1986 • 111 citations

Mechanism of inactivation of thyroid peroxidase by thioureylene drugs

1982 • 107 citations

Hypothyroxinemia and hypothermia in rats in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin administration

1983 • 107 citations

In Vitro Assays for Recombinogenic Activity of Chemical Carcinogens and Related Compounds With <italic>Saccharomyces cerevisiae</italic> D3<xref ref-type="fn" rid="FN2">2</xref>

1979 • 106 citations

Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans

1978 • 105 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) as a potent and persistent thyroxine agonist: a mechanistic model for toxicity based on molecular reactivity.

1985 • 103 citations

Volume of Sella Turcica in Normal Subjects and in Patients with Primary Hypothyroidism and Hyperthyroidism

1976 • 102 citations

A Point Mutation in the c- myc Locus of a Burkitt Lymphoma Abolishes Binding of a Nuclear Protein

1988 • 102 citations

Regulation of theαand Thyrotropinβ-Subunit Messenger Ribonucleic Acids by Thyroid Hormones*

1985 • 99 citations

The specific induction of myc protooncogene expression in normal human B cells is not a sufficient event for acquisition of competence to proliferate.

1985 • 97 citations

Stimulation of cell proliferation and inhibition of differentiation expression by tumor-promoting phorbol esters in dog thyroid cells in primary culture.

1986 • 96 citations

DNA-damaging activity in vivo and bacterial mutagenicity of sixteen aromatic amines and azo-derivatives, as related quantitatively to their carcinogenicity

1981 • 95 citations

Effect of polychlorinated biphenyl (PCB) on the thyroid gland of rats. Ultrastructural and biochemical investigations.

1977 • 94 citations

Nature of the enhancement of hepatic uridine diphosphate glucuronyltransferase activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats

1975 • 93 citations

Neoplasia and Internal Environment

1955 • 90 citations

Alterations in Thyroxine Metabolism Produced by Cutaneous Application of Microscope Immersion Oil: Effects Due to Polychlorinated Biphenyls

1976 • 89 citations

Changes in thyroid hormones and thyroxine glucuronidation in hamsters compared with rats following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1987 • 89 citations

Dissociation of growth and function in the rat thyroid during prolonged goitrogen administration

1982 • 87 citations

Location of Epidermal Growth Factor Receptors on Porcine Thyroid Follicle Cells and Receptor Regulation by Thyrotropin*

1986 • 87 citations

Thyroid carcinoma in an endemic goiter area, Cali, Colombia

1966 • 86 citations

Effect of long-term amiodarone therapy on thyroid hormone levels and thyroid function

1985 • 84 citations

Incidence of Thyroid Cancer in Women in Relation to Previous Exposure to Radiation Therapy and History of Thyroid Disease<xref ref-type="fn" rid="FN2">2</xref>

1984 • 83 citations

Norepinephrine and Thyroid-Stimulating Hormone Induce Inositol Phosphate Accumulation in FRTL-5 Cells

1986 • 82 citations

Comparative Neoplastic Transformation Responses of Balb/3T3 Cells, Syrian Hamster Embryo Cells, and Rauscher Murine Leukemia Virus-Infected Fischer 344 Rat Embryo Cells to Chemical Carcinogens

1981 • 81 citations

Thyroid cancer and thyrotoxicosis in the United States: Their relation to endemic goiter

1961 • 81 citations

Promoting effects of phenobarbital and barbital on development of thyroid tumors in rats treated with N-bis(2-hydroxypropyl)nitrosamine

1982 • 81 citations

Nitrosation in vitro and in vivo by sodium nitrite, and mutagenicity of nitrogenous pesticides

1977 • 80 citations

The Effect of Radioactive Iodine Alone and in Combination with Methylthiouracil and Acetylaminofluorene upon Tumour Production in the Rat's Thyroid Gland

1950 • 79 citations

Changes in DNA and Weight of Thyroid Glands During Hyperplasia and Involution

1970 • 79 citations

Effects of one-year administration of ethylenethiourea upon the thyroid of the rat

1973 • 78 citations

Goitrogens and thyroid follicular cell neoplasia: Evidence for a threshold process

1988 • 76 citations

Mutagenic and recombinogenic action of pesticides in Aspergillus nidulans

1977 • 73 citations

Multiple Effects of 5,5′-Diphenylhydantoin on the Thyroid Hormone System*

1984 • 72 citations

Enhanced biliary excretion of thyroxine glucuronide in rats pretreated with benzpyrene

1968 • 72 citations

Thyroid status and thermogenesis in rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1986 • 72 citations

The experimental production of thyroid tumors in the rat exposed to prolonged treatment thiouracil

1950 • 71 citations

Growth Factor Control of Rat Thyroid Follicular Cell Proliferation

1986 • 71 citations

A link between liver microsomal enzyme activity and thyroid hormone metabolism in man.

1983 • 70 citations

ENDOCRINE EFFECTS OF LITHIUM

1978 • 70 citations

MYXŒDEMA FROM RESORCINOL OINTMENT APPLIED TO LEG ULCERS

1950 • 70 citations

Mutagenicity of aminophenyl and nitrophenyl ethers, sulfides, and disulfides

1979 • 66 citations

Geographic Pathology of Thyroid Diseases

1981 • 65 citations

Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea.

1983 • 64 citations

Development of carcinoma of the thyroid in iodine-deficient mice

1966 • 64 citations

The effect of hypophysectomy on the experimental production of rat thyroid neoplasms.

1970 • 64 citations

[11] Purification of cytochrome P-450 and P-448 from rat liver microsomes

1978 • 63 citations

Pituitary cybernetics and neoplasia.

1969 • 59 citations

Dietary iodine deficiency as a tumor promoter and carcinogen in male F344/NCr rats.

1986 • 59 citations

The Role of Initiating and Promoting Factors in the Pathogenesis of Tumours of the Thyroid

1948 • 59 citations

Avian Thyroid: Effect of p , p ′-DDT on Size and Activity

1969 • 59 citations

Triiodothyronine (T₃) Regulation of Thyrotropin Subunit Gene Transcription Is Proportional to T₃Nuclear Receptor Occupancy*

1986 • 57 citations

HYPOTHYROIDISM IN DIABETICS TREATED WITH SULPHONYLUREA

1965 • 56 citations

Stimulation by forskolin of the thyroid adenylate cyclase, cyclic amp accumulation and iodine metabolism

1983 • 54 citations

Goitres in rats fed polychlorinated biphenyls

1977 • 54 citations

The diagnosis of malignancy in dyshormonogenetic goitre

1981 • 54 citations

Correlated Functional and Morphometric Study of Thyroid Hyperplasia Induced by Iodine Deficiency*

1981 • 53 citations

Thyrotroph cell adenoma of the human pituitary gland associated with primary hypothyroidism: clinical and morphological features

1980 • 53 citations

Characterization and Regulations of the Receptor for Insulin-Like Growth Factor-I in the FRTL-5 Rat Thyroid Follicular Cell Line*

1987 • 53 citations

TSH AND CAMP ENHANCE EXPRESSION OF THE MYC PROTO-UNCOGENE IN CULTURED THYROID CELLS

1985 • 53 citations

Lack of correlation between the capability of inducing sister-chromatid exchanges in vivo and carcinogenic potency, for 16 aromatic amines and azo derivatives

1983 • 51 citations

Comparative toxicity of polychlorinated biphenyl and polybrominated biphenyl in the rat liver: light and electron microscopic alterations after subacute dietary exposure.

1978 • 51 citations

Microbiological mutagenicity studies of pesticides in vitro

1978 • 51 citations

Studies on Endemic and Experimental Goitre

1936 • 50 citations

ENDEMIC INFANTILE HYPOTHYROIDISM IN A SEVERE ENDEMIC GOITRE AREA OF CENTRAL AFRICA

1984 • 50 citations

Expression of the myc Cellular Proto-Oncogene in Human Thyroid Tissue*

1986 • 48 citations

Goitrogen-induced thyroid growth in the rat: a quantitative morphometric study

1982 • 47 citations

Regulation of Thyrotropin-Releasing Hormone Receptors and Responses by L-Triiodothyronine in Dispersed Rat Pituitary Cell Cultures*

1982 • 47 citations

Effect of Polybrominated Biphenyls (PBB) on the Pituitary-Thyroid Axis of the Rat

1981 • 46 citations

Effect of thyroidectomy and thyroxine on 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity

1985 • 46 citations

Enhanced in vitro hepatic glucuronidation of thyroxine in rats following cutaneous application or ingestion of polychlorinated biphenyls

1976 • 46 citations

Ethylenethiourea (ETU), a carcinogenic and mutagenic metabolite of ethylenebis-dithiocarbamate

1974 • 46 citations

An interlaboratory comparison of transformation in syrian hamster embryo cells with model and coded chemicals

1986 • 46 citations

Desensitisation of rat thyroid to the growth-stimulating action of TSH during prolonged goitrogen administration Persistence of refractoriness following withdrawal of stimulation

1982 • 45 citations

Collaborative Studies on the Salmonella/Microsome Mutagenicity Assay

1979 • 44 citations

Some Effects of DDT, Toxaphene and Polychlorinated Biphenyl on Thyroid Function in Bobwhite Quail

1974 • 44 citations

GROWTH IN THE CELL POPULATIONS OF THE THYROID GLAND OF RATS TREATED WITH THIOURACIL

1957 • 43 citations

Increase in the Number of Type II Insulin-Like Growth Factor Receptors during Propylthiouracil-Induced Hyperplasia in the Rat Thyroid*

1986 • 41 citations

Ethylene thiourea: thyroid function in two groups of exposed workers.

1984 • 40 citations

The Escherichia coli WP2/WP100 rec assay for detection of potential chemical carcinogens

1983 • 40 citations

Thyrotropic tumor syndrome. A multiglandular disease induced by sustained deficiency of thyroid hormones.

1973 • 40 citations

Interaction of Insulin-Like Growth Factor I with Porcine Thyroid Cells Cultured in Monolayer*

1987 • 40 citations

Carcinogenic Effect of 100, 250 and 500 Rad X-Rays on the Rat Thyroid Gland

1974 • 40 citations

Induction and Reversibility of Thyroid Proliferative Changes in Rats Given an Antithyroid Compound

1986 • 39 citations

Mutagenicity of N-acetyl and N,N′-diacetyl derivatives of 3 aromatic amines used as epoxy-resin hardeners

1985 • 39 citations

Studies on the Pathogenesis of Colloid Goiter

1967 • 38 citations

Promotion of <italic>N</italic>-Methyl-<italic>N</italic>-Nitrosourea-Induced Thyroid Tumors by Iodine Deficiency in F344/NCr Rats<xref ref-type="fn" rid="FN2">2</xref>

1984 • 38 citations

The Development of Thyroid and Pituitary Tumours in the Rat Two Years after Partial Thyroidectomy

1962 • 38 citations

Neoplastic Response of F344 Rats and B6C3F<sub>1</sub> Mice to the Polymer and Dyestuff Intermediates 4,4′-Methylenebis(<italic>N</italic>,<italic>N</italic>-dimethyl)-benzenamine, 4,4′-Oxydianiline, and 4,4′-Methylenedianiline<xref ref-type="fn" rid="FN2">2</xref>

1984 • 36 citations

In VitroEvidence for an Intracellular Mechanism Limiting the Thyroid Follicular Cell Growth Response to Thyrotropin

1985 • 36 citations

Endemic Goitre in Babbits. I. Incidence and Characteristics.

1928 • 36 citations

Thyroidal and vascular changes in mice following chronic treatment with goitrogens and carcinogens.

1947 • 36 citations

THE EFFECT OF METHYLCHOLANTHRENE ON BILIARY THYROXINE EXCRETION IN NORMAL AND GUNN RATS

1973 • 35 citations

Changes Induced in the Pigeon Thyroid by p,p prime -DDE and Dieldrin

1972 • 35 citations

INDUCTION OF THYROTROPIN-DEPENDENT THYROID TUMORS BY THYROTROPES¹

1960 • 35 citations

The Effects of Phenytoin (Diphenylhydantoin) on the Extrathyroidal Turnover of Thyroxine, 3,5,3′-Triiodothyronine, 3,3′,5′-Triiodothyronine, and 3′,5′-Diiodothyronine in Man*

1985 • 35 citations

Mechanism of action of antithyroid compounds.

1955 • 35 citations

Chemical enhancement of SA7 virus transformation of hamster embryo cells: Evaluations by interlaboratory testing of diverse chemicals

1986 • 34 citations

Studies on Experimental Goitre. I: The Effect of Brassica Seed Diets on Rats

1941 • 34 citations

Effect of propylthiouracil on the thyroid tumorigenesis induced by N-bis(2-hydroxypropyl)nitrosamine in rats

1984 • 34 citations

Effect of varying the duration of exposure to phenobarbital on its enhancement of N-bis(2-hydroxypropyl)nitrosamine-induced thyroid tumorigenesis in male Wistar rats

1983 • 33 citations

Thyroid cell proliferation in rats and induction of tumors by X-rays.

1975 • 33 citations

Epidemiology of Thyroid Cancer

1978 • 32 citations

Effect of Isomers of DDD on thyroid and adrenal function in rats

1968 • 31 citations

Studies on bilirubin and steroid glucuronidation by rat liver microsomes

1975 • 30 citations

Studies on Goitrogenic Agents in Food

1957 • 30 citations

Epidermal Growth Factor: Effect on Circulating Thyroid Hormone Levels in Sheep*

1986 • 30 citations

Mutagenicity and toxicity of amitrole. I. Drosophila tests

1976 • 29 citations

Dissociation Between Thyroxine Metabolism and Hormonal Action in Phenobarbital-Treated Rats

1971 • 28 citations

Is c- Myc Protein Directly Involved in DNA Replication?

1988 • 28 citations

Studies of the goitrogenic and tumorigenic effect of two goitrogens in combination with hypophysectomy or thyroid hormone treatment

1980 • 27 citations

The growth curve of the rat thyroid under a goitrogenic stimulus.

1969 • 27 citations

In vivo mutagenic interaction of nitrite and ethylenethiourea

1975 • 27 citations

Studies on Experimental Goitre. VI. Thyroid Adenomata in Rats on Brassica Seed Diet

1945 • 27 citations

The goitrogenic effect of Phenobarbital-Na on the rat thyroid

1969 • 27 citations

Differences in aetiology and thyroid function in endemic goitre between rural and urban areas of the Darfur region of the Sudan

1985 • 26 citations

Reversibility of ethylenethiourea-induced thyroid lesions

1983 • 26 citations

4,4′-Diaminodiphenylmethane: Promoting Effect on the Development of Thyroid Tumors in Rats Treated With <italic>N</italic>-Bis(2-hydroxypropyl)nitrosamine<xref ref-type="fn" rid="FN2">2</xref>

1984 • 26 citations

Metabolic Formation of Toxic Metabolites

1983 • 25 citations

The Biliary Excretion of Thyroxine and Its GlucuronicAcid Conjugate in Normal and Gunn Rats

1973 • 24 citations

Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the biliary excretion of indocyanine green in rat.

1973 • 24 citations

Effect of long-term suppression and stimulation of rat thyroid with special reference to lysosomes*1, *2

1971 • 24 citations

Polybrominated biphenyl toxicosis in rats fed an iodine-deficient, iodine-adequate, or iodine-excess diet.

1978 • 23 citations

Further studies on induction and growth of thyrotropic pituitary tumors in mice.

1956 • 23 citations

Protein kinase C activators modulate differentiated thyroid function in vitro

1986 • 22 citations

The metabolism of foreign compounds in rats after treatment with polychlorinated biphenyls (PCBs)

1975 • 22 citations

In Vitro and In Vivo Refractoriness to Thyrotropin Stimulation of Iodine Organification and Thyroid Hormone Secretion

1979 • 22 citations

In vivo formation of N-nitroso compounds and detection of their mutagenic activity in the host-mediated assay.

1977 • 21 citations

Hypophyseal Changes Induced by Thyroid Deficiency and Thyroxine Administration as Revealed by Immunochemical Staining1

1971 • 21 citations

Experimental thyroid tumours.

1970 • 21 citations

Studies on Experimental Goitre. II: Changes in the Anterior Pituitary of the Rat, Produced by Brassica Seed Diet

1941 • 21 citations

A comparative study on the mutagenicity of ethylenethiourea in bacterial and mammalian test systems

1977 • 20 citations

Amitrole-induced cell transformation and gene mutations in Syrian hamster embryo cells in culture

1984 • 20 citations

Positive Regulation of the Guinea Pig Thyrotropin Receptor*

1985 • 19 citations

Induction of dominant-lethal mutations after administration of ethylenethiourea in combination with nitrite or of N-nitroso-ethylenethiourea in mice

1978 • 18 citations

Aetiological consideration of thyroid carcinoma.

1970 • 17 citations

The Goitrogenic Effect of 4,4'-Oxydianiline in Rats and Mice

1978 • 17 citations

Effects of Hypothyroidism on Development of Nitrosomethylurea-Induced Tumors of the Mammary Gland, Thyroid Gland, and Other Tissues

1982 • 17 citations

Hypothyroidism related to ethionamide.

1970 • 14 citations

The effect of oxidation of the sulfur atom on the mutagenicity of ethylenethiourea

1982 • 14 citations

Adenoma and Carcinoma, Pars Distalis, Rat

1983 • 14 citations

Mutagenicity and toxicity of amitrole. II. Human lymphocyte culture tests

1976 • 14 citations

Antithyroid studies; the goitrogenic activity of some thioureas, pyrimidines and miscellaneous compounds.

1945 • 12 citations

Regulation of the Rat Thyrotropin Receptor in Vitro*

1981 • 12 citations

Effect of Salicylate on the Biliary Excretion of Thyroxine in Rats

1963 • 12 citations

Oxyphenbutazone-induced goitre

1977 • 11 citations

Acute Thyroid Hormone Withdrawal Rapidly Increases the Thyrotropinβandα-Subunit Messenger Ribonucleic Acids in Mouse Thyrotropic Tumors*

1986 • 11 citations

Antithyroid studies; the goitrogenic activity of certain chemotherapeutically active sulfones and related compounds.

1945 • 10 citations

Properties of enzyme activities involved in protein phosphorylatino-dephosphorylation of the thyroid plasma membranes

1982 • 10 citations

Studies on the Detection of Carcinogens Using a Mammalian Cell Transformation Assay with Liver Homogenate Activation

1980 • 9 citations

On the development of metastasizing tumors of the rat thyroid gland after combined administration of nitrosomethylurea and methylthiouracil

1980 • 8 citations

Studies on Experimental Goitre. iv. The Effect of Di-Iodotyrosine and Thyroxine on the Goitrogenic Action of Brassica Seeds

1943 • 8 citations

An Essential Role of Thyroxine and Triiodothyronine Balance in Establishing Normal Pituitary-Thyroid Feedback Control in Goitrogen-Treated Rats

1968 • 7 citations

Effect of 4,4′-Oxydianiline on the Thyroid and Pituitary Glands of F344 Rats: A Morphologic Study With the Use of the Immunoperoxidase Method<xref ref-type="fn" rid="FN2">2</xref>

1985 • 6 citations

On the mechanism of polychlorinated biphenyl-induced hypobilirubinaemia

1975 • 5 citations

Follicular Cell Hyperplasia, Thyroid, Rat

1983 • 5 citations

Histochemical Identification of Hormones in Pituitary Tumors, Rat

1983 • 3 citations

Adenoma, Thyroid, Mouse

1983 • 3 citations

Thyroid cancer: epidemiology.

1980 • 3 citations