Puzzling diabetic transgenic mice: a lesson for human type 1 diabetes?

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

ROLE OF ABERRANT HLA-DR EXPRESSION AND ANTIGEN PRESENTATION IN INDUCTION OF ENDOCRINE AUTOIMMUNITY

1983 • 1,275 citations

In Situ Characterization of Autoimmune Phenomena and Expression of HLA Molecules in the Pancreas in Diabetic Insulitis

1985 • 935 citations

ABERRANT EXPRESSION OF HLA-DR ANTIGEN ON THYROCYTES IN GRAVES' DISEASE: RELEVANCE FOR AUTOIMMUNITY

1983 • 710 citations

Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

1988 • 476 citations

The histopathology of the pancreas in Type I (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom

1986 • 453 citations

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

1987 • 451 citations

Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin.

1983 • 441 citations

Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells

1988 • 343 citations

Organ‐Specific Autoimmunity: A 1986 Overview

1986 • 274 citations

Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells

1987 • 269 citations

Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic β cells

1988 • 266 citations

Lectin-induced expression of DR antigen on human cultured follicular thyroid cells

1983 • 233 citations

Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells

1987 • 201 citations

Aberrant Expression of HLA-DR Antigens by Insulin-Containing β-Cells in Recent-Onset Type I Diabetes MelIitus

1986 • 180 citations

Pre-diabetes in the spontaneously diabetic BB/E rat: lymphocyte subpopulations in the pancreatic infiltrate and expression of rat MHC class II molecules in endocrine cells

1985 • 111 citations

Large-Scale Anisotropy in the Hubble Flow

1986 • 68 citations

Regulation of MHC Protein Expression in Pancreatic β-Cells by Interferon-γ and Tumor Necrosis Factor-α

1988 • 67 citations

Expression of class II major histocompatibility complex antigens on pancreatic B cells in the NOD mouse

1987 • 53 citations

Aberrant expression of HLA-DR antigens by insulin-containing beta-cells in recent-onset type I diabetes mellitus

1986 • 44 citations

Intolerable secretion in tolerant transgenic mice

1988 • 42 citations

Class-II and IL 2 receptor positive cells in the pancreas of NOD mice

1987 • 36 citations

Does T-cell restriction to Ia limit the need for self-tolerance?

1985 • 29 citations

Tolerance, restriction and the Mls enigma

1988 • 9 citations