Relevance of the chemical charge of rhodamine dyes to multiple drug resistance

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

1986 • 1,903 citations

Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins

1986 • 1,058 citations

Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy.

1981 • 913 citations

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies.

1970 • 752 citations

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells.

1985 • 398 citations

Pleiotropic phenotype of colchicine‐resistant CHO cells: Cross‐resistance and collateral sensitivity

1976 • 314 citations

Mechanism of cross-resistance between vincristine and daunorubicin in Ehrlich ascites tumor cells.

1978 • 231 citations

The basis of multidrug resistance in mammalian cells: Homology with bacterial transport

1986 • 134 citations

Cross resistance between vinca alkaloids and anthracyclines in Ehrlich ascites tumor in vivo.

1972 • 115 citations

Cross-resistance to rhodamine 123 in Adriamycin- and daunorubicin-resistant Friend leukemia cell variants.

1984 • 74 citations

Reversal of resistance to rhodamine 123 in adriamycin-resistant Friend leukemia cells.

1985 • 69 citations

Membrane potential differences between adriamycin-sensitive and -resistant cells as measured by flow cytometry

1989 • 57 citations

Resistance and Cross-Resistance of Cultured Leukemia P388 Cells to Vincristine, Adriamycin, Adriamycin Analogs, and Actinomycin D<xref ref-type="fn" rid="FN2">2</xref>

1978 • 57 citations

Reversal of multidrug resistance by non-antitumor anthracycline analogs.

1984 • 26 citations