Interferon-β Prevents the Upregulation of Interleukin-8 Expression in Human Melanoma Cells

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.

1988 • 3,038 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Interleukin-8 as a Macrophage-Derived Mediator of Angiogenesis

1992 • 2,130 citations

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture.

1990 • 1,147 citations

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

1988 • 1,039 citations

Regulation of Rransendothelial Neutrophil Migration by Endogenous Interleukin-8

1991 • 813 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung.

1990 • 678 citations

Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF

1989 • 602 citations

Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice.

1988 • 462 citations

Tumor necrosis factor alpha and interferon gamma synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-kB-like binding sites of the interleukin 8 gene.

1992 • 450 citations

Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8.

1991 • 442 citations

Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas.

1995 • 442 citations

Production of interleukin-8 by human dermal fibroblasts and keratinocytes in response to interleukin-1 or tumour necrosis factor.

1989 • 422 citations

Role of organ selectivity in the determination of metastatic patterns of B16 melanoma.

1980 • 417 citations

Interleukin-8. A corneal factor that induces neovascularization.

1992 • 385 citations

Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.

1986 • 384 citations

Close link between reduction of c-myc expression by interferon and G0/G1 arrest

1985 • 358 citations

Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice.

1994 • 357 citations

Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells

1990 • 274 citations

Monokine-induced Neutrophil Chemotactic Factor Gene Expression in Human Fibroblasts

1989 • 272 citations

Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells.

1990 • 237 citations

A Human Melanoma Line Heterogeneous With Respect to Metastatic Capacity in Athymic Nude Mice<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref><xref ref-type="fn" rid="FN4">4</xref>

1984 • 231 citations

Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes.

1990 • 211 citations

Human Alveolar Macrophage Gene Expression of Interleukin-8 by Tumor Necrosis Factor-α, Lipopolysaccharide, and Interleukin-1β

1990 • 208 citations

IFN-beta 2, B cell differentiation factor 2, or hybridoma growth factor (IL-6) is expressed and released by human epidermal cells and epidermoid carcinoma cell lines.

1989 • 205 citations

Immunohistological detection of interleukin 1-like molecules and tumour necrosis factor in human epidermis before and after UVB-irradiation in vivo

1988 • 190 citations

Downregulation of interleukin 8 gene expression in human fibroblasts: unique mechanism of transcriptional inhibition by interferon.

1992 • 184 citations

Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis

1991 • 181 citations

IL-1 alpha or tumor necrosis factor-alpha stimulate release of three NAP-1/IL-8-related neutrophil chemotactic proteins in human dermal fibroblasts.

1990 • 179 citations

Induction of haptotactic migration of melanoma cells by neutrophil activating protein/interleukin-8

1990 • 175 citations

Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5‐fluorouracil

1992 • 175 citations

Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system.

1992 • 152 citations

Structure determination of a human lymphocyte derived neutrophil activating peptide (LYNAP)

1988 • 146 citations

Ultraviolet B irradiation promotes tumorigenic and metastatic properties in primary cutaneous melanoma via induction of interleukin 8.

1995 • 144 citations

Induction of circulating IL-1 receptor antagonist by IFN treatment.

1993 • 137 citations

Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells.

1994 • 136 citations

Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice

1992 • 134 citations

Regulation of interleukin-8 expression in human melanoma cells by the organ environment.

1995 • 115 citations

Different Growth Pattern and Biologic Behavior of Human Renal Cell Carcinoma Implanted Into Different Organs of Nude Mice<xref ref-type="fn" rid="FN2">2</xref>

1987 • 108 citations

Interferon-α and interferon-γ down-regulate the production of interleukin-8 and ENA-78 in human monocytes

1995 • 105 citations

IFN-gamma selectively inhibits lipopolysaccharide-inducible JE/monocyte chemoattractant protein-1 and KC/GRO/melanoma growth-stimulating activity gene expression in mouse peritoneal macrophages.

1994 • 99 citations

Expression and Secretion of Leukocyte Chemotactic Cytokines by Normal Human Melanocytes and Melanoma Cells

1991 • 96 citations

Mechanisms of organ selective tumour growth by bloodborne cancer cells

1988 • 88 citations

IL-2 up-regulates but IFN-gamma suppresses IL-8 expression in human monocytes.

1993 • 88 citations

Cytokine production by the bladder carcinoma cell line 5637: rapid analysis of mRNA expression levels using a cDNA-PCR procedure.

1991 • 87 citations

Interferon selectively inhibits the expression of mitochondrial genes: a novel pathway for interferon-mediated responses.

1990 • 86 citations

Human recombinant interferons‐beta and ‐gamma decrease gelatinase production and invasion by human KG‐2 renal‐carcinoma cells

1994 • 80 citations

Type 1 Interferon as an Antiinflammatory Agent: Inhibition of Lipopolysaccharide-Induced Interleukin-lβ and Induction of Interleukin-1 Receptor Antagonist

1995 • 52 citations

Alpha-interferon inhibits the expression of heavy chain mu messenger RNA in Daudi cells.

1988 • 37 citations

Virus Replication and Induction of Interferon in Human Epidermal Keratinocytes Following Infection with Herpes Simplex Virus

1984 • 32 citations

Regulation of c-fgr proto-oncogene expression in Burkitt's lymphoma cells: effect of interferon treatment and relationship to EBV status and c-myc mRNA levels.

1989 • 21 citations

c-fos mRNA expression in macrophages is downregulated by interferon-gamma at the posttranscriptional level.

1991 • 20 citations

Coding region structure of interleukin-8 gene of human lung giant cell carcinoma LU65C cells that produce LUCT/interleukin-8: homogeneity in interleukin-8 genes

1990 • 15 citations

Normal Human Keratinocytes Contain an Interferon‐like Protein That May Modulate Their Growth and Differentiation

1988 • 11 citations

Regulation of c-mycRNA and Its Proteins in Daudi Cells by Interferon-β

1987 • 10 citations

Down regulation of lamins A and C by murine interferon ?*1

1991 • 5 citations