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Hereditary deficiency of the sixth component of complement in man. I. Immunochemical, biologic, and family studies.

Data up to Jan 2025

Published1974
Citations126
References49

Total Citations Per Year

Abstract

References (49)

THE C3-ACTIVATOR SYSTEM: AN ALTERNATE PATHWAY OF COMPLEMENT ACTIVATION

1971 • 827 citations

Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum

1966 • 651 citations

Molecular Basis of Complement Action

1971 • 533 citations

THE ROLE OF SERUM COMPLEMENT IN CHEMOTAXIS OF LEUKOCYTES IN VITRO

1965 • 404 citations

Granulocyte Chemotaxis: An Improved in Vitro Assay Employing 51Cr-Labeled Granulocytes

1973 • 328 citations

Kabat and Mayer's Experimental Immunochemistry

1962 • 307 citations

HOMOZYGOUS DEFICIENCY OF C3 IN A PATIENT WITH REPEATED INFECTIONS

1972 • 270 citations

Chemotaxis of polymorphonuclear leukocytes from patients with rheumatoid arthritis

1971 • 268 citations

Practical haematology

1969 • 268 citations

A Familial Deficiency of the Phagocytosis-Enhancing Activity of Serum Related to a Dysfunction of the Fifth Component of Complement (C5)

1970 • 259 citations

Further studies on the chemotactic factor of complement and its formation in vivo.

1966 • 222 citations

DEFICIENCY OF THE FIFTH COMPONENT OF COMPLEMENT IN MICE WITH AN INHERITED COMPLEMENT DEFECT

1967 • 210 citations

THE PROPERDIN SYSTEM AND IMMUNITY

1956 • 173 citations

Hereditary C2 Deficiency with Some Manifestations of Systemic Lupus Erythematosus

1972 • 170 citations

Polymorphonuclear Leukocyte Chemotactic Activity in Rabbit Serum and Guinea Pig Serum Treated with Immune Complexes: Evidence for C5a as the Major Chemotactic Factor

1970 • 168 citations

Immunochemical approaches to problems in microbiology

1961 • 164 citations

The Sugar-Water Test for Paroxysmal Nocturnal Hemoglobinuria

1966 • 163 citations

A neutrophil chemotatic factor derived from C'5 upon interaction of guinea pig serum with endotoxin.

1969 • 154 citations

Paroxysmal nocturnal hemoglobinuria

1990 • 153 citations

Hereditary deficiency of the second component of complement (C'2) in man.

1966 • 152 citations

Studies in vivo and in vitro on an abnormality in the metabolism of C3 in a patient with increased susceptibility to infection

1970 • 143 citations

C1r deficiency: an inborn error associated with cutaneous and renal disease

1972 • 127 citations

THE PROPERDIN SYSTEM AND IMMUNITY. IV. THE HEMOLYSIS OF ERYTHROCYTES FROM PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA 1

1956 • 116 citations

Quantitative studies on the bactericidal actions of serum and complement. I. A rapid photometric growth assay for bactericidal activity.

1956 • 115 citations

C2 Deficiency DEVELOPMENT OF LUPUS ERYTHEMATOSUS

1973 • 110 citations

A Neutrophil Chemotactic Factor Derived from C′5 upon Interaction of Guinea Pig Serum with Endotoxin

1969 • 101 citations

Lupus-Erythematosus-like Syndrome with a Familial Defect of Complement

1972 • 98 citations

Bactericidal and Opsonic Properties of C4-Deficient Guinea Pig Serum

1972 • 95 citations

DEFICIENCY OF C1r IN HUMAN SERUM

1970 • 90 citations

Inherited deficiency of the third component of human complement (C′3)

1969 • 85 citations

Hereditary deficiency of the second component of complement (C2) in man: correlation of C2 haemolytic activity with immunochemical measurements of C2 protein.

1970 • 83 citations

A BLOOD COAGULATION ABNORMALITY IN RABBITS DEFICIENT IN THE SIXTH COMPONENT OF COMPLEMENT (C6) AND ITS CORRECTION BY PURIFIED C6

1971 • 82 citations

Hereditary Deficiency of the Second Component of Complement (C′2) in Man: Further Observations on a Second Kindred

1967 • 81 citations

IDENTIFICATION OF THE COMPONENTS OF COMPLEMENT PARTICIPATING IN THE ANTIGLOBULIN REACTION.

1963 • 80 citations

Genetic Aspects of the Complement System

1971 • 78 citations

DEFICIENCY OF THE SIXTH COMPONENT OF COMPLEMENT IN RABBITS WITH AN INHERITED COMPLEMENT DEFECT

1966 • 77 citations

Mechanisms of Immune Lysis of Red Blood Cells In Vitro I. PAROXYSMAL NOCTURNAL HEMOGLOBINURIA CELLS

1973 • 74 citations

The Complement System of Man

1972 • 73 citations

Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum

1966 • 70 citations

Purpura, Arthralgia, and IgM-IgG Cryoglobulinemia with Rheumatoid Factor Activity

1971 • 61 citations

Studies of an Additional Kindred with Hereditary Deficiency of the Second Component of Human Complement (C2) and Description of a New Method for the Quantitation of C2

1968 • 56 citations

Chemotaxis of Polymorphonuclear Leukocytes from Patients with Systemic Lupus Erythematosus and Felty's Syndrome

1972 • 43 citations

Hereditary deficiency of the sixth component of complement in man. II. Studies of hemostasis.

1974 • 40 citations

IMMUNE BACTERICIDAL ACTIVITY OF COMPLEMENT. SEPARATION AND DESCRIPTION OF INTERMEDIATE STEPS.

1964 • 40 citations

Protective Function of C6 in Rabbits Treated with Bacterial Endotoxin

1971 • 36 citations

Studies on chemotaxis. XII. Generation of chemotactic activity for polymorphonuclear leucocytes in sera with complement dificiencies.

1969 • 35 citations

Complement components of a haemolytically deficient strain of rabbits.

1968 • 32 citations

Hereditary Deficiency of the Second Component of Complement in Man: An Immunochemical Study

1969 • 23 citations

Immune hemolysis. I. Differing susceptibility of three genetic types of sheep red cells.

1972 • 23 citations

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Hereditary deficiency of the sixth component of complement in man. I. Immunochemical,… (1974) – Journal of Clinical Investigation | Metascience Observatory Explorer