Physical properties of cytoplasm

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton

1993 • 2,947 citations

Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape.

1993 • 1,765 citations

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

1993 • 1,124 citations

Viscoelastic properties of vimentin compared with other filamentous biopolymer networks.

1991 • 694 citations

Actin-Binding Protein Requirement for Cortical Stability and Efficient Locomotion

1992 • 567 citations

Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

1990 • 522 citations

Microtrabecular lattice of the cytoplasmic ground substance. Artifact or reality.

1979 • 516 citations

Hindered diffusion of inert tracer particles in the cytoplasm of mouse 3T3 cells.

1987 • 395 citations

Enhanced Motility in NIH 3T3 Fibroblasts That Overexpress Gelsolin

1991 • 321 citations

Determinants of the translational mobility of a small solute in cell cytoplasm.

1993 • 295 citations

The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.

1992 • 285 citations

Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape

1992 • 274 citations

Viscoelasticity of the sarcomere matrix of skeletal muscles. The titin-myosin composite filament is a dual-stage molecular spring

1993 • 251 citations

Low viscosity in the aqueous domain of cell cytoplasm measured by picosecond polarization microfluorimetry.

1991 • 250 citations

Cytoskeletal remodeling during growth cone-target interactions.

1993 • 250 citations

Resemblance of actin-binding protein/actin gels to covalently crosslinked networks

1990 • 240 citations

Getting the message from the gene to the synapse: sorting and intracellular transport of RNA in neurons

1992 • 235 citations

Tension and compression in the cytoskeleton of PC 12 neurites.

1985 • 224 citations

A novel fluorescence ratiometric method confirms the low solvent viscosity of the cytoplasm

1993 • 212 citations

Signal transduction and the actin cytoskeleton: the roles of MARCKS and profilin

1992 • 203 citations

A Conformational Change in the Actin Subunit Can Change the Flexibility of the Actin Filament

1993 • 203 citations

The spatial distribution of polyribosomes in 3T3 cells and the associated assembly of proteins into the skeletal framework

1980 • 194 citations

Confinement as a determinant of macromolecular structure and reactivity

1992 • 192 citations

Tracer diffusion of globular proteins in concentrated protein solutions.

1988 • 173 citations

Mechanical properties of cytoskeletal polymers

1991 • 172 citations

Gene Expression During Normal and Malignant Differentiation

1986 • 157 citations

The cytoskeleton and mRNA localization

1992 • 157 citations

The Submicroscopic Properties of Cytoplasm as a Determinant of Cellular Function

1988 • 143 citations

Macromolecular diffusion in crowded solutions

1993 • 141 citations

Titin is an extraordinarily long, flexible, and slender myofibrillar protein.

1984 • 141 citations

Effect of ATP on actin filament stiffness

1990 • 138 citations

Association of Glycolytic Enzymes with the Cytoskeleton

1992 • 138 citations

Targeted disruption of the ABP-120 gene leads to cells with altered motility.

1992 • 125 citations

Mechanics of fibroblast locomotion: quantitative analysis of forces and motions at the leading lamellas of fibroblasts.

1990 • 122 citations

Aldolase exists in both the fluid and solid phases of cytoplasm [published erratum appears in J Cell Biol 1988 Dec;107(6 Pt 1):following 2463]

1988 • 118 citations

“Macromolecular crowding”: thermodynamic consequences for protein-protein interactions within the T4 DNA replication complex.

1990 • 111 citations

Ligand-sensitive binding of actin-binding protein to immunoglobulin G Fc Receptor I (FcγRI)

1991 • 106 citations

Cytoplasmic viscosity near the cell plasma membrane: measurement by evanescent field frequency-domain microfluorimetry

1993 • 98 citations

Nucleotide exchange, structure, and mechanical properties of filaments assembled from ATP-actin and ADP-actin.

1992 • 96 citations

Nuclear‐Cytoskeletal interactions: Evidence for physical connections between the nucleus and cell periphery and their alteration by transformation

1992 • 94 citations

Viscoelasticity of F-actin measured with magnetic microparticles.

1989 • 93 citations

Synchrony of cell spreading and contraction force as phagocytes engulf large pathogens

1993 • 92 citations

Self-diffusion and probe diffusion in dilute and semidilute aqueous solutions of dextran

1991 • 86 citations

Tracer diffusion in F-actin and Ficoll mixtures. Toward a model for cytoplasm

1990 • 83 citations

Protein kinase C associates with intermediate filaments and stress fibers

1992 • 72 citations

Microcompartmentation of glycolytic enzymes in cultured cells.

1992 • 72 citations

Investigation of microtubule assembly and organization accompanying tension-induced neurite initiation

1993 • 64 citations

Cytoarchitecture of size-excluding compartments in living cells

1993 • 62 citations

Acoustic microscopy of cultured cells

1991 • 60 citations

Subcellular compartmentalization by local differentiation of cytoplasmic structure

1988 • 59 citations

Liquid crystal domains and thixotropy of filamentous actin suspensions.

1990 • 58 citations

Holobiochemistry: The effect of local environment upon the equilibria and rates of biochemical reactions

1990 • 57 citations

Evidence that intermediate filament reorganization is induced by ATP-dependent contraction of the actomyosin cortex in permeabilized fibroblasts

1991 • 55 citations

Biophysics of the leading lamella

1988 • 51 citations

Microtubules, ribosomes, and RNA: Evidence for cytoplasmic localization and translational regulation

1993 • 48 citations

Identification and characterization of two huge protein components of the brush border cytoskeleton: evidence for a cellular isoform of titin.

1992 • 47 citations

‘Macromolecular crowding’ is a primary factor in the organization of the cytoskeleton

1992 • 45 citations

Microinterferometry of the movement of dry matter in fibroblasts

1989 • 42 citations

Picosecond Rotation of Small Polar Fluorophores in the Cytosol of Sea Urchin Eggs

1991 • 35 citations

Association of mRNA with the cytoskeletal framework: its role in the regulation of gene expression.

1992 • 32 citations

An absolute rate theory model for tension control of axonal elongation

1992 • 32 citations

Organic osmolytes increase cytoplasmic viscosity in kidney cells

1992 • 30 citations

Nucleotide exchange and rheometric studies with F-actin prepared from ATP- or ADP-monomeric actin

1993 • 29 citations

Cellular automaton model of the actin cytoskeleton

1993 • 28 citations

Specific types of prosomes are associated to subnetworks of the intermediate filaments in PtK1 cells.

1992 • 27 citations

Studies on the structure of actin gels using time correlation spectroscopy of fluorescent beads

1992 • 25 citations

Production of a unique antibody specific for membrane ruffles and its use to characterize the behavior of two distinct types of ruffles.

1993 • 18 citations

Association of mRNA with the cytoskeletal framework: its role in the regulation of gene expression.

1992 • 18 citations

Heat-induced disturbances of intracellular movement and the consistency of the aqueous cytoplasm in HeLa S-3 cells: a laser-Doppler and proton NMR study.

1991 • 14 citations

Analysis of dynamic and stationary pattern formation in the cell cortex

1992 • 13 citations

The control of cellular motility and the role of gelsolin

1991 • 10 citations

Kinematics of Cytoplasmic Deformation in Neutrophils During Active Motion

1990 • 10 citations

Signal transduction through the cytoplasm

1986 • 9 citations

Glycoprotein Ib- and actin-binding regions in human platelet actin-binding protein

1991 • 4 citations

Laser Doppler Microscopy Of Living Cytoplasm

1987 • 2 citations