Production of a unique antibody specific for membrane ruffles and its use to characterize the behavior of two distinct types of ruffles.

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Promotion of microtubule assembly in vitro by taxol

1979 • 3,521 citations

Dynamic instability of microtubule growth

1984 • 3,187 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

THE ROLE OF THREE CYTOPLASMIC FIBERS IN BHK-21 CELL MOTILITY

1971 • 453 citations

The locomotion of fibroblasts in culture

1970 • 336 citations

Calcium-regulated modulator protein interacting agents inhibit smooth muscle calcium-stimulated protein kinase and ATPase.

1980 • 335 citations

Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments.

1983 • 319 citations

Rapid induction of morphological changes in human carcinoma cells A-431 by epidermal growth factors.

1979 • 300 citations

Evidence that microtubule depolymerization early in the cell cycle is sufficient to initiate DNA synthesis

1981 • 202 citations

A rapid procedure for preparing fluorescein-labeled specific antibodies from whole antiserum: its use in analyzing cytoskeletal architecture.

1983 • 189 citations

Identification and localization of immunoreactive forms of caldesmon in smooth and nonmuscle cells: a comparison with the distributions of tropomyosin and alpha-actinin.

1985 • 170 citations

Locomotory activity of epithelial cells in culture

1975 • 168 citations

Induction of circular membrane ruffling on human fibroblasts by platelet-derived growth factor

1988 • 156 citations

Divalent cation modulation of fibronectin binding to heparin and to DNA.

1982 • 151 citations

Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin.

1986 • 128 citations

Effect of colcemid on fibroblast motility

1971 • 128 citations

Intermediate Filament Networks: Organization And Possible Functions Of A Diverse Group Of Cytoskeletal Elements

1986 • 120 citations

Intermediate filament collapse is an AtP-dependent and actin-dependent process

1989 • 100 citations

Insulin-induced formation of ruffling membranes of KB cells and its correlation with enhancement of amino acid transport.

1984 • 90 citations

Isolation and characterization of keratin-like proteins from cultured cells with fibroblastic morphology.

1984 • 85 citations

Caldesmon: A common actin‐linked regulatory protein in the smooth muscle and nonmuscle contractile system

1988 • 77 citations

Interaction of microtubule-associated proteins with actin filaments. Studies using the fluorescence-photobleaching recovery technique.

1984 • 22 citations

An agent or agents produced by virus-transformed cells cause unregulated ruffling in untransformed cells.

1986 • 22 citations