Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3‐L1 adipocytes

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

2001 • 4,874 citations

The hormone resistin links obesity to diabetes

2001 • 4,720 citations

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

2002 • 4,335 citations

C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus

2001 • 4,289 citations

Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia

2001 • 3,408 citations

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

1995 • 3,159 citations

Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients

2000 • 3,142 citations

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

2003 • 3,114 citations

Obesity and insulin resistance

2000 • 3,076 citations

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

2001 • 2,534 citations

AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity

1996 • 2,229 citations

cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (AdiposeMost Abundant Gene Transcript 1)

1996 • 2,082 citations

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

2002 • 2,081 citations

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

2001 • 1,903 citations

PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

2001 • 1,659 citations

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl–CoA carboxylase inhibition and AMP-activated protein kinase activation

2002 • 969 citations

Isolation and Characterization of GBP28, a Novel Gelatin-Binding Protein Purified from Human Plasma

1996 • 919 citations

The role of TNFα and TNF receptors in obesity and insulin resistance

1999 • 771 citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

1982 • 727 citations

Hormonal Regulation of Adiponectin Gene Expression in 3T3-L1 Adipocytes

2002 • 665 citations

Tumor Necrosis Factor-α-induced Insulin Resistance in 3T3-L1 Adipocytes Is Accompanied by a Loss of Insulin Receptor Substrate-1 and GLUT4 Expression without a Loss of Insulin Receptor-mediated Signal Transduction

1997 • 543 citations

Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes

2003 • 534 citations

Involvement of AMP-Activated Protein Kinase in Glucose Uptake Stimulated by the Globular Domain of Adiponectin in Primary Rat Adipocytes

2003 • 446 citations

Effects of Growth Hormone on Insulin Action in Man: Mechanisms of Insulin Resistance, Impaired Suppression of Glucose Production, and Impaired Stimulation of Glucose Utilization

1982 • 434 citations

36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO

1991 • 432 citations

Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.

1997 • 428 citations

Synthetic Peroxisome Proliferator-Activated Receptor-γ Agonist, Rosiglitazone, Increases Plasma Levels of Adiponectin in Type 2 Diabetic Patients

2002 • 413 citations

Pathophysiology and Pharmacological Treatment of Insulin Resistance*

2000 • 354 citations

Adiponectin gene expression is inhibited by β‐adrenergic stimulation via protein kinase A in 3T3‐L1 adipocytes

2001 • 271 citations

Insulin resistance in acromegaly: defects in both hepatic and extrahepatic insulin action

1986 • 232 citations

β3-Adrenergic Stimulation Differentially Inhibits Insulin Signaling and Decreases Insulin-induced Glucose Uptake in Brown Adipocytes

1999 • 226 citations

Pathogenesis of the Dawn Phenomenon in Patients with Insulin-Dependent Diabetes Mellitus

1985 • 213 citations

Essential Role of Insulin Receptor Substrate-2 in Insulin Stimulation of Glut4 Translocation and Glucose Uptake in Brown Adipocytes

2000 • 170 citations

Pathophysiology and Pharmacological Treatment of Insulin Resistance

2000 • 169 citations

Essential Role of Insulin Receptor Substrate 1 in Differentiation of Brown Adipocytes

2001 • 165 citations

Interleukin (IL)-6 mRNA Expression is Stimulated by Insulin, Isoproterenol, Tumour Necrosis Factor Alpha, Growth Hormone, and IL-6 in 3T3-L1 Adipocytes

2003 • 152 citations

Tumor Necrosis Factor α Is a Negative Regulator of Resistin Gene Expression and Secretion in 3T3-L1 Adipocytes

2001 • 140 citations

Growth Hormone Induces Cellular Insulin Resistance by Uncoupling Phosphatidylinositol 3-Kinase and Its Downstream Signals in 3T3-L1 Adipocytes

2001 • 106 citations

Cortisol and the metabolic syndrome in South Asians

2003 • 106 citations

The mouse homologue of the human acidic ribosomal phosphoprotein PO: a highly conserved polypeptide that is under translational control

1989 • 91 citations

Visceral Obesity and Diabetes

1999 • 85 citations

Growth hormone signalling and its regulation: Preventing too much of a good thing

2001 • 83 citations

Isoproterenol inhibits resistin gene expression through a G_S‐protein‐coupled pathway in 3T3‐L1 adipocytes

2001 • 80 citations

Visceral obesity and the role of the somatotropic axis in the development of metabolic complications

2001 • 23 citations

The Effect ofIn VivoThyroxine Treatment on Insulin Receptors, Glucose Transport and GLUT4 in Rat Adipocytes

1997 • 13 citations