Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid β-protein precursor-like protein-2

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

1987 • 1,316 citations

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 • 1,098 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II

1989 • 460 citations

Protease nexin-II, a potent anti-chymotrypsin, shows identity to amyloid β-protein precursor

1989 • 437 citations

Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidinobenzoate esters. Titration of the enzymes

1969 • 433 citations

Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).

1994 • 349 citations

The amyloid precursor protein of Alzheimer's disease is released by human platelets.

1990 • 322 citations

Protease Nexin-II(amyloid β-protein Precursor): a Platelet α-Granule Protein

1990 • 299 citations

Platelet Coagulation Factor XI _a -Inhibitor, a Form of Alzheimer Amyloid Precursor Protein

1990 • 299 citations

Isolation of alcohol oxidase and two other methanol regulatable genes from the yeast Pichia pastoris.

1985 • 271 citations

Molecular cloning of the cDNA for a human amyloid precursor protein homolog: Evidence for a multigene family

1993 • 193 citations

In vivo significance of kinetic constants of protein proteinase inhibitors

1984 • 150 citations

Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor.

1990 • 145 citations

Continuous Production of a Novel Lysozyme via Secretion from the Yeast, Pichia pastoris

1989 • 112 citations

Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa.

1993 • 109 citations

Protease nexin-2/amyloid β-protein precursor in blood is a platelet-specific protein

1991 • 63 citations

High level expression, purification, and characterization of the Kunitz-type protease inhibitor domain of protease nexin-2/amyloid β-protein precursor

1992 • 59 citations

Characterization of the clotting activities of structurally different forms of activated factor IX. Enzymatic properties of normal human factor IXa alpha, factor IXa beta, and activated factor IX Chapel Hill.

1985 • 51 citations

Potential Role of Protease Nexin‐2/Amyloid β‐Protein Precursor as a Cerebral Anticoagulant^a

1992 • 45 citations

Co-distribution of protease nexin-1 and protease nexin-2 in brains of non-human primates

1993 • 28 citations

Expression, purification and characterization of a Kunitz‐type protease inhibitor domain from human amyloid precursor protein homolog

1994 • 22 citations

The acceleration by polylysine of the activation of factor X by factor IXa

1982 • 16 citations