Electroconformational coupling and membrane protein function

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

The effect of sodium ions on the electrical activity of the giant axon of the squid

1949 • 3,479 citations

POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES

1943 • 2,733 citations

Gene transfer into mouse lyoma cells by electroporation in high electric fields.

1982 • 2,413 citations

Physics of chemoreception

1977 • 1,844 citations

Modern Electrochemistry

1970 • 1,743 citations

Structural chemistry and molecular biology

1968 • 1,698 citations

The Hofmeister effect and the behaviour of water at interfaces

1985 • 1,533 citations

Deviations from Ohm's Law in Weak Electrolytes

1934 • 1,178 citations

Calculations of electrostatic interactions in biological systems and in solutions

1984 • 992 citations

Time, Structure, and Fluctuations

1978 • 991 citations

The α-helix dipole and the properties of proteins

1978 • 985 citations

THREE-DIMENSIONAL STRUCTURE OF MEMBRANE AND SURFACE PROTEINS

1984 • 959 citations

ROLE OF REVERSIBLE OXIDATION-REDUCTION OF ENZYME THIOLS-DISULFIDES IN METABOLIC REGULATION

1985 • 840 citations

Electrostatic Potentials at Membrane-Solution Interfaces

1977 • 822 citations

Theory of Protein Titration Curves. I. General Equations for Impenetrable Spheres

1957 • 798 citations

Electrostatic Effects in Proteins

1978 • 734 citations

Dielectric and electronic properties of biological materials

1979 • 711 citations

Tissue interactions with nonionizing electromagnetic fields.

1981 • 652 citations

Noise-Induced Transitions: Theory and Applications in Physics, Chemistry, and Biology

2007 • 620 citations

Electric field-induced cell-to-cell fusion

1982 • 580 citations

The role of the α-helix dipole in protein function and structure

1985 • 517 citations

Dielectric and Electronic Properties of Biological Materials

1980 • 506 citations

Formation and resealing of pores of controlled sizes in human erythrocyte membrane

1977 • 493 citations

Oscillatory Phenomena in Biochemistry

1971 • 486 citations

ELECTROSTATIC INTERACTIONS IN MEMBRANES AND PROTEINS

1986 • 439 citations

The responses of cells to electrical fields: a review.

1985 • 430 citations

The Biological Effects of Microwaves and Related Questions

1980 • 417 citations

Noise-induced transitions: Theory and applications in physics, chemistry and biology

1988 • 415 citations

Voltage-induced pore formation and hemolysis of human erythrocytes

1977 • 377 citations

The asymmetric distribution of charges on the surface of horse cytochrome c. Functional implications.

1982 • 374 citations

Reversible electrical breakdown of lipid bilayer membranes: A charge-pulse relaxation study

1979 • 369 citations

Introduction to Membrane Noise

1981 • 358 citations

Free Energy Transduction in Biology

1977 • 342 citations

On the functional proton current pathway of electron transport phosphorylation

1979 • 340 citations

Neurites grow faster towards the cathode than the anode in a steady field

1979 • 319 citations

Electric field induced transient pores in phospholipid bilayer vesicles

1981 • 313 citations

Selenium-Dependent Enzymes

1980 • 299 citations

Long Range Coherence and the Action of Enzymes

1970 • 298 citations

Electrical Properties of Egg Cell Membranes

1979 • 277 citations

Optical imaging of cell membrane potential changes induced by applied electric fields

1986 • 273 citations

A Non-Operative Salvage of Surgically-Resistant Pseudarthroses and Non-Unions by Pulsing Electromagnetic Fields

1977 • 270 citations

A structural model of the acetylcholine receptor channel based on partition energy and helix packing calculations

1984 • 260 citations

Voltage-induced conductance in human erythrocyte membranes

1979 • 246 citations

Membrane potentials and sodium channels: Hypotheses for growth regulation and cancer formation based on changes in sodium channels and gap junctions

1986 • 221 citations

Characterization of the respiration-dependent Na+ pump in the marine bacterium Vibrio alginolyticus.

1982 • 213 citations

Enhanced Spinal Cord Regeneration in Lamprey by Applied Electric Fields

1981 • 201 citations

863 — Absorption and conversion of electric field energy by membrane bound atpases

1986 • 199 citations

Activation of electrogenic Rb+ transport of (Na,K)-ATPase by an electric field.

1984 • 175 citations

Tailoring the pH dependence of enzyme catalysis using protein engineering

1985 • 168 citations

Proton Electrochemical Gradients and Energy-Transduction Processes

1982 • 163 citations

Energetics of the calcium-transporting ATPase.

1984 • 155 citations

Bilayer Lipid Membranes

1978 • 146 citations

Survival of sucrose-loaded erythrocytes in the circulation

1978 • 145 citations

Reversible and irreversible modification of erythrocyte membrane permeability by electric field

1985 • 142 citations

Voltage-dependent channel formation by rods of helical polypeptides

1986 • 136 citations

Stimulation of a Ouabain-Sensitive Rb+ uptake in human erthrocytes with an external electric field

1983 • 135 citations

Energy Coupling in Membrane Vesicles of Escherichia coli

1974 • 130 citations

Membrane‐bound ATP synthesis generated by an external electrical field

1976 • 129 citations

Light-induced giant dipoles in simple model compounds for photosynthesis

1986 • 127 citations

Evidence of voltage-induced channel opening in Na/K ATPase of human erythrocyte membrane

1980 • 126 citations

Ionic channels with conformational substates

1985 • 122 citations

The effect of an applied electric field on the charge recombination kinetics in reaction centers reconstituted in planar lipid bilayers

1985 • 109 citations

Interactions between intrinsic membrane protein and electric field. An approach to studying nerve excitability

1978 • 104 citations

Voltage modulation of membrane permeability and energy utilization in cells

1983 • 103 citations

Effects of the α-helix dipole upon the functioning and structure of proteins and peptides

1985 • 102 citations

Physics ; part ii

1962 • 99 citations

The rate of ATP synthesis as a function of ΔpH in normal and dithiothreitol-modified chloroplasts

1985 • 98 citations

Modulation of coupling factor ATPase activity in intact chloroplasts. Reversal of thiol modulation in the dark

1982 • 98 citations

Electrostatic stabilization in myoglobin. The pH dependence of summed electrostatic contributions

1979 • 94 citations

Synthesis of adenosine triphosphate by an artificially imposed electrochemical proton gradient in bovine heart submitochondrial particles.

1975 • 93 citations

A novel type of energetics in a marine alkali‐tolerant bacterium

1983 • 88 citations

Electrostatic effects and the dynamics of enzyme reactions at the surface of plant cells

1986 • 83 citations

Charge clusters and the orientation of membrane proteins

1982 • 82 citations

Excitability Phenomena in Artificial Membranes

1962 • 77 citations

Ion selectivity of temperature-induced and electric field induced pores in dipalmitoylphosphatidylcholine vesicles

1985 • 74 citations

Fluctuations and Noise in Kinetic Systems

1973 • 74 citations

Relation between the initial kinetics of ATP synthesis and of conformational changes in the chloroplast ATPase studied by external field pulses

1981 • 69 citations

Geometric effects of reduction of dimensionality in interfacial reactions

1984 • 68 citations

Chemical electric field effects in biological macromolecules

1986 • 67 citations

Acetylcholine receptor in planar lipid bilayers. Characterization of the channel properties of the purified nicotinic acetylcholine receptor from Torpedo californica reconstituted in planar lipid bilayers.

1984 • 65 citations

Conformational transitions in fluorescein-labeled (Na,K)ATPase reconstituted into phospholipid vesicles.

1986 • 61 citations

Electrical potential accelerates the E1P(Na)----E2P conformational transition of (Na,K)-ATPase in reconstituted vesicles.

1986 • 61 citations

A very short peptide makes a voltage‐dependent ion channel: The critical length of the channel domain of colicin E1

1986 • 58 citations

Net ATP synthesis in H+-ATPase macroliposomes by an external electric field

1979 • 58 citations

On the physico-chemical basis of voltage-dependent molecular gating mechanisms in biological membranes

1978 • 54 citations

Linkage graphs: a study in the thermodynamics of macromolecules

1984 • 53 citations

Interaction of the maltose-binding protein with membrane vesicles of Escherichia coli

1982 • 47 citations

Microscopic description of voltage effects on ion-driven cotransport systems

1986 • 46 citations

Electrostatic stabilization in myoglobin. Interactive free energies between individual sites

1979 • 45 citations

Voltage-driven ATP synthesis by beef heart mitochondrial F0F1-ATPase.

1984 • 44 citations

Mechanisms of the multiphasic kinetics in the folding and unfolding of globular proteins

1978 • 41 citations

Adenosine 5'-triphosphate synthesis in Escherichia coli submitted to a microsecond electric pulse

1986 • 40 citations

The effect of field fluctuation on a macromolecular system

1975 • 39 citations

Chemoreception of sugars by an excitable liquid membrane

1986 • 39 citations

Nonlinear oscillations in biology and chemistry

1987 • 39 citations

Interfacial reaction dynamics

1985 • 37 citations

225 - The surface compartment model of the steady state excitable membrane

1978 • 33 citations

Voltage-dependent activation in purified reconstituted sodium channels from rabbit T-tubular membranes.

1986 • 33 citations

Predominantly Electrochemical Nature of Biological Power-producing Reactions

1967 • 32 citations

Conformational flexibility of membrane proteins in electric fields

1983 • 32 citations

Net Adenosine Triphosphate Synthesis Driven by an External Electric Field in Rat liver Mitochondria1

1982 • 30 citations

Enzyme Activities in Polarized Cell Membranes

1968 • 29 citations

Voltage-noise-induced transitions in electrically excitable membranes

1981 • 28 citations

Binding of quinacrine, a fluorescent local anesthetic probe, to mammalian axonal membranes. Evidence for a local anesthetic receptor site.

1982 • 28 citations

Electrical excitability of artificial enzyme membranes

1982 • 25 citations

The nature of local chemical potentials

1982 • 25 citations

Some unexpected consequences of a simple physical mechanism for voltage-dependent gating in biological membranes

1984 • 25 citations

A Basic Biological Step?

1969 • 24 citations

Dynamics of proteins

1984 • 22 citations

A theory for the apparent "negative second Wien effect" observed in electric-field-jump studies of suspensions

1984 • 16 citations

Properties of ion channels inferred from the surface compartment model (SCM)

1984 • 15 citations

Enzyme Dynamics and Regulation

1988 • 15 citations

Bimodal effects of cellular amino acids on Na+-dependent amino acid transport in ehrlich cells

1980 • 14 citations

CHEMICAL TRANSITIONS OF BIOPOLYMERS INDUCED BY AN ELECTRIC FIELD AND THEIR EFFECTS IN DIELECTRICS AND BIREFRINGENCE*

1977 • 14 citations

[10] Function of protonmotive force in translocation of protein across membranes

1986 • 12 citations

Differentiation between equilibrium and nonequilibrium kinetic systems by noise analysis

1978 • 12 citations

[5] Changes of surface and membrane potentials in biomembranes

1986 • 12 citations

[6] Rate of redox reactions related to surface potential and other surface-related parameters in biological membranes

1986 • 11 citations

Asymmetry of fluctuation with respect to time reversal in steady states of biological systems

1982 • 10 citations

Studies in Irreversible Thermodynamics. I. Internal Equilibrium and the Reciprocal Relations

1964 • 10 citations

Sensitivity of membranes to their environment. Role of stochastic processes

1984 • 8 citations

Millisecond kinetics of ATP synthesis driven by externally imposed electrochemical potentials in chloroplasts.

1985 • 8 citations

Structural aspects and orientation mechanism of mitochondrial F1-adenosine triphosphatase. Evidence for a negative electric birefringence due to a permanent moment perpendicular to the long axes of the particle

1986 • 6 citations

Non-equilibrium voltage noise generated by ion transport through pores

1985 • 5 citations

Nonequilibrium voltage fluctuations in biological membranes

1986 • 4 citations

Structure, Function, and Assembly of Membrane Proteins

1987 • 4 citations

Kinetics of actin-myosin binding. I. An exactly soluble one-variable model

1987 • 4 citations

Energy transfer and molecular switching II. Muscle contraction and enzymatic reactions

1982 • 3 citations

Nonequilibrium voltage fluctuations in biological membranes

1986 • 3 citations

On exploring the basis for slow and fast oscillations in cellular systems

1982 • 3 citations

728—The ion-pair concept in macromolecular dynanmics

1984 • 3 citations