Interleukin 2 production and responsiveness in individuals with acquired immunodeficiency syndrome and the generalized lymphadenopathy syndrome

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Pneumocystis cariniiPneumonia and Mucosal Candidiasis in Previously Healthy Homosexual Men

1981 • 2,717 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

Qualitative Analysis of Immune Function in Patients with the Acquired Immunodeficiency Syndrome

1985 • 737 citations

Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.

1985 • 545 citations

Long-Term Cultures of HTLV-III—Infected T Cells: a Model of Cytopathology of T-Cell Depletion in AIDS

1986 • 537 citations

Interleukin 2

1984 • 497 citations

Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immune deficiency syndrome.

1983 • 414 citations

Immunologic Abnormalities in the Acquired Immunodeficiency Syndrome

1985 • 380 citations

ACCURACY IN DIAGNOSIS OF GASTRIC AND DUODENAL LESIONS BY GENERAL PRACTITIONERS, HOSPITAL CLINICIANS, AND RADIOLOGISTS.

1965 • 192 citations

Defective T-cell response to PHA and mitogenic monoclonal antibodies in male homosexuals with acquired immunodeficiency syndrome and itsin vitro correction by interleukin 2

1983 • 146 citations

Mechanism of T cell activation. II. Antigen- and lectin-dependent acquisition of responsiveness to TCGF is a nonmitogenic, active response of resting T cells.

1981 • 115 citations

Depressed interleukin 2 receptor expression in acquired immune deficiency and lymphadenopathy syndromes.

1984 • 113 citations

The mechanism of retrovirus suppression of human T cell proliferation in vitro.

1983 • 101 citations

IL 2 receptor induction on human T lymphocytes: role for IL 2 and monocytes.

1985 • 100 citations

HUMAN RECOMBINANT INTERLEUKIN-2 PARTLY RECONSTITUTES DEFICIENT IN-VITRO IMMUNE RESPONSES OF LYMPHOCYTES FROM PATIENTS WITH AIDS

1984 • 88 citations

Epidemiology of Human T-Lymphotropic Virus Type III and the Risk of the Acquired Immunodeficiency Syndrome

1985 • 86 citations

Interleukin 2 enhances the natural killer cell activity of acquired immunodeficiency syndrome patients through a gamma-interferon-independent mechanism.

1985 • 86 citations

Fatal Lymphoma after Transplantation of Cultured Thymus in Children with Combined Immunodeficiency Disease

1979 • 84 citations

A rapid method for separating functionally intact human T lymphocytes with monoclonal antibodies

1981 • 77 citations

Production of and in vitro response to interleukin 2 in the acquired immunodeficiency syndrome.

1985 • 74 citations

Study of activated T cell in man

1986 • 53 citations

Partial restoration of impaired interleukin-2 production and Tac antigen (putative interleukin-2 receptor) expression in patients with acquired immune deficiency syndrome by isoprinosine treatment in vitro.

1985 • 49 citations

Sera from patients with the acquired immunodeficiency syndrome inhibit production of interleukin-2 by normal lymphocytes.

1985 • 47 citations

Mechanisms of T-Cell Functional Deficiency in the Acquired Immunodeficiency Syndrome

1985 • 45 citations

Clonal analysis of T lymphocytes in the acquired immunodeficiency syndrome. Evidence for an abnormality affecting individual helper and suppressor T cells.

1985 • 43 citations

Interleukin-2 production and response to exogenous interleukin-2 in a patient with the acquired immune deficiency syndrome (AIDS).

1984 • 41 citations

Interleukin-2 production by persons with the generalized lymphadenopathy syndrome or the acquired immune deficiency syndrome

1985 • 39 citations

Defective in vitro T cell colony formation in the acquired immunodeficiency syndrome.

1985 • 36 citations

Autologous mixed lymphocyte reaction in man. XIV. Deficiency of the autologous mixed lymphocyte reaction in acquired immune deficiency syndrome (AIDS) and AIDS related complex (ARC). In vitro effect of purified interleukin-1 and interleukin-2.

1984 • 36 citations

Immunoregulatory circuits in the acquired immune deficiency syndrome and related complex. Production of and response to interleukins 1 and 2, NK function and its enhancement by interleukin-2 and kinetics of the autologous mixed lymphocyte reaction.

1985 • 35 citations

Is there correlation of T cell proliferative functions and surface marker phenotypes in patients with acquired immune deficiency syndrome or lymphadenopathy syndrome?

1985 • 33 citations

The relationship of abnormalities of cellular immunity to antibodies to HTLV-III in homosexual men

1986 • 30 citations

Abnormal lymphocyte response to exogenous interleukin-2 in homosexuals with acquired immune deficiency syndrome (AIDS) and AIDS related complex (ARC).

1985 • 25 citations

Diminished interleukin 2 production and receptor generation characterize the acquired immunodeficiency syndrome

1985 • 21 citations

Inhibition of interleukin 2 production and expression of the interleukin 2 receptor by plasma from acquired immune deficiency syndrome patients

1986 • 18 citations

Inhibition of interleukin-2-induced T-cell proliferation by sera from patients with the acquired immune deficiency syndrome

1986 • 10 citations

IL-2 PRODUCTION AND RESPONSE IN VITRO BY THE LEUKOCYTES OF PATIENTS WITH ACQUIRED IMMUNE DEFICIENCY SYNDROME*

1983 • 9 citations