IL-2 PRODUCTION AND RESPONSE IN VITRO BY THE LEUKOCYTES OF PATIENTS WITH ACQUIRED IMMUNE DEFICIENCY SYNDROME*

A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.

1981 • 1,366 citations

Severe Acquired Immunodeficiency in Male Homosexuals, Manifested by Chronic Perianal Ulcerative Herpes Simplex Lesions

1981 • 1,242 citations

T cell growth factor receptors. Quantitation, specificity, and biological relevance

1981 • 1,087 citations

The functional relationship of the interleukins.

1980 • 660 citations

Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line.

1980 • 436 citations

Two distinct factors are required for induction of T-cell growth

1980 • 416 citations

Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immune deficiency syndrome.

1983 • 414 citations

Acquired Immunodeficiency With Reversed T4/T8 Ratios in Infants Born to Promiscuous and Drug-Addicted Mothers

1983 • 401 citations

T-Lymphocyte Subpopulations in Homosexual Men

1982 • 351 citations

Purification and some characteristics of human T-cell growth factor from phytohemagglutinin-stimulated lymphocyte-conditioned media.

1980 • 291 citations

Human T-lymphocyte growth factor: regulation of growth and function of T lymphocytes

1981 • 289 citations

Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen.

1983 • 202 citations

ACCURACY IN DIAGNOSIS OF GASTRIC AND DUODENAL LESIONS BY GENERAL PRACTITIONERS, HOSPITAL CLINICIANS, AND RADIOLOGISTS.

1965 • 192 citations

Relationship of cell cycle to recovery of IL 2 activity from human mononuclear cells, human and mouse T cell lines.

1981 • 148 citations

Cellular origin of interleukin 2 (IL 2) in man: evidence for stimulus-restricted IL 2 production by T4+ and T8+ T lymphocytes.

1982 • 147 citations

Defective T-cell response to PHA and mitogenic monoclonal antibodies in male homosexuals with acquired immunodeficiency syndrome and itsin vitro correction by interleukin 2

1983 • 146 citations

Effect of interleukin 1 on human thymocytes and purified human T cells.

1981 • 112 citations

Immunological characterization of homosexual males.

1983 • 108 citations

Human T lymphocyte/monocyte interaction in response to lectin: kinetics of entry into the S-phase.

1981 • 99 citations

HUMAN RECOMBINANT INTERLEUKIN-2 PARTLY RECONSTITUTES DEFICIENT IN-VITRO IMMUNE RESPONSES OF LYMPHOCYTES FROM PATIENTS WITH AIDS

1984 • 88 citations

Deficient autologous mixed lymphocyte reaction in Kaposi's sarcoma associated with deficiency of Leu-3+ responder T cells.

1983 • 67 citations

Surface antigen changes occurring in short-term cultures of activated human T lymphocytes: Analysis by flow cytometry

1982 • 30 citations

Human Interleukin 2: Physiology, Biochemistry, and Pathophysiology in Lymphoblastic Leukemias and Immunodeficiency Syndromes

1983 • 14 citations

Interaction between repeated skin testing with recall antigens and temporal fluctuations of in vitro lymphocyte blastogenesis in cancer patients

1977 • 13 citations

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