Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
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References (16)
Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling
1995 • 2,907 citations
Histological Typing of Tumours of the Central Nervous System
1993 • 1,493 citations
A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway
1997 • 861 citations
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
1998 • 560 citations
Proliferation of human malignant astrocytomas is dependent on Ras activation
1997 • 331 citations
The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene.
1998 • 313 citations
Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice
1998 • 306 citations
The Akt kinase: Molecular determinants of oncogenicity
1998 • 294 citations
Akt-Dependent and -Independent Survival Signaling Pathways Utilized by Insulin-Like Growth Factor I
1998 • 248 citations
Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas.
1996 • 228 citations
Amplification of the epidermal‐growth‐factor‐receptor gene correlates with different growth behaviour in human glioblastoma
1994 • 204 citations
Expression of insulin‐like growth factors I and II and their receptor mRNAs in primary human astrocytomas and meningiomas; in vivo studies using in situ hybridization and immunocytochemistry
1992 • 124 citations
Histological Classification of Tumours of the Central Nervous System
1993 • 84 citations
Insulin Receptor Substrate 2 And Shc Play Different Roles In Insulin-like Growth Factor I Signaling
1998 • 81 citations
Signal transduction pathways and their relevance in human astrocytomas.
1997 • 76 citations
Basic fibroblast growth factor: A potential autocrine regulator of human glioma cell growth
1990 • 68 citations