Rat brain cathepsin L: Characterization and differentiation from cathepsin B utilizing opioid peptides

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

The C-Fragment of β-Lipotropin: An Endogenous Neuroleptic or Antipsychotogen?

1976 • 427 citations

Mapping the active site of papain with the aid of peptide substrates and inhibitors

1970 • 410 citations

Cathepsin L

1977 • 341 citations

Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles

1987 • 335 citations

New Observations on the Substrate Specificity of Cathepsin C (Dipeptidyl Aminopeptidase I)

1969 • 225 citations

Action of rat liver cathepsin L on collagen and other substrates.

1982 • 221 citations

Human liver cathepsin L

1985 • 191 citations

Elastinolytic activity of human cathepsin L

1986 • 185 citations

Intracellular degradation of newly synthesized secretory proteins

1983 • 158 citations

Cloning and characterization of a mouse cysteine proteinase.

1986 • 137 citations

Purification and Tissue Distribution of Rat Cathepsin L1

1986 • 136 citations

An Aminopeptidase from Bovine Brain Which Catalyzes the Hydrolysis of Enkephalin

1981 • 125 citations

Dipeptidyl-aminopeptidase III of rat brain. Selective affinity for enkephalin and angiotensin.

1982 • 110 citations

The purification and properties of cathepsin L from rabbit liver

1984 • 105 citations

Purification and Some Properties of a Myofibrillar Protein-Degrading Protease, Cathepsin L, from Rabbit Skeletal Muscle<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1980 • 96 citations

Thermostable Endogenous Inhibitors of Cathepsins B and H

1979 • 96 citations

Cathepsin L inactivates alpha 1-proteinase inhibitor by cleavage in the reactive site region.

1986 • 96 citations

The major excreted protein (MEP) of transformed mouse cells and cathepsin L have similar protease specificity

1986 • 66 citations

Action of cathepsin L on the oxidized B‐chain of bovine insulin

1980 • 60 citations

Different immunolocalizations of cathepsins B, H, and L in the liver.

1985 • 57 citations

A comparison of the behavior of chymotrypsin and cathepsin B towards peptidyl diazomethyl ketones

1979 • 56 citations

Purification and Properties of Brain Cathepsin B

1979 • 53 citations

The Role of Lysosomes and Proteases in Hormone Secretion and Degradation

1981 • 53 citations

Porcine spleen cathepsin B is an exopeptidase.

1986 • 52 citations

Preferential action of rat brain cathepsin B as a peptidyl dipeptidase converting pro-opioid oligopeptides

1986 • 48 citations

A general framework of cysteine-proteinase mechanism deduced from studies on enzymes with structurally different analogous catalytic-site residues Asp-158 and −161 (papain and actinidin), Gly-196 (cathepsin B) and Asn-165 (cathepsin H). Kinetic studies up to pH 8 of the hydrolysis of N-α-benzyloxycarbonyl-<scp>l</scp>-arginyl-<scp>l</scp>-arginine 2-naphthylamide catalysed by cathepsin B and of <scp>l</scp>-arginine 2-naphthylamide catalysed by cathepsin H.

1985 • 47 citations

Action of human liver cathepsin B on the oxidized insulin B chain

1983 • 43 citations

The limited proteolysis of rabbit muscle aldolase by cathepsin B1

1978 • 34 citations

Inactivation of cathepsin B1 by diazomethyl ketones

1977 • 34 citations

Opioid peptides: molecular pharmacology, biosynthesis, and analysis.

1986 • 33 citations

Pepstatin-insensitive proteolytic activity of rat liver lysosomes. Isolation and purification of a new pepstatin-insensitive proteolytic enzyme from rat liver lysosomes.

1977 • 29 citations

Cerebrocystatin suppresses degradation of myelin basic protein by purified brain cysteine proteinase

1983 • 26 citations

Rat mammary gland in culture secretes a stable high molecular weight form of cathepsin L

1985 • 18 citations

Purification and characterisation of collagenolytic cathepsins from rabbit liver

1982 • 16 citations

Formation of desTyr dynorphins 5–17 by a purified cytosolic aminopeptidase of rat brain

1984 • 15 citations

Conversion of met-enkephalin-Arg6-Phe7 by a purified brain carboxypeptidase (cathepsin A)

1981 • 14 citations

METABOLISM OF ENKEPHALIN ANALOGUES AND SURROGATES HAVING ENHANCED PHARMACOLOGIC ACTIVITIES *

1982 • 7 citations