Structural insights into clathrin-mediated endocytosis

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR-mediated protein-protein interactions

1998 • 820 citations

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

1995 • 816 citations

CLATHRIN-COATED VESICLE FORMATION AND PROTEIN SORTING: An Integrated Process

1997 • 793 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α

1998 • 759 citations

Three-Dimensional Structure of the Armadillo Repeat Region of β-Catenin

1997 • 678 citations

A Structural Explanation for the Recognition of Tyrosine-Based Endocytotic Signals

1998 • 582 citations

Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

1998 • 576 citations

A presynaptic inositol-5-phosphatase

1996 • 573 citations

Structure of importin-β bound to the IBB domain of importin-α

1999 • 552 citations

Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid

1999 • 536 citations

Developmental selection of var gene expression in Plasmodium falciparum

1998 • 532 citations

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

1994 • 519 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Adaptors for Clathrin-Mediated Traffic

1999 • 500 citations

Synaptic Vesicle Endocytosis Impaired by Disruption of Dynamin-SH3 Domain Interactions

1997 • 479 citations

The Road Taken

2000 • 434 citations

Molecular Bases for the Recognition of Tyrosine-based Sorting Signals

1999 • 414 citations

A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.

1996 • 408 citations

Clathrin and adaptors

1998 • 383 citations

Structural View of the Ran–Importin β Interaction at 2.3 Å Resolution

1999 • 344 citations

Structure of the nuclear transport complex karyopherin-β2–Ran˙GppNHp

1999 • 340 citations

High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides

1994 • 310 citations

Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site

1998 • 310 citations

Peptide-in-groove interactions link target proteins to the β-propeller of clathrin

2000 • 285 citations

A Structural Explanation for the Binding of Multiple Ligands by the α-Adaptin Appendage Domain

1999 • 284 citations

Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis

1999 • 265 citations

The Medium Subunits of Adaptor Complexes Recognize Distinct but Overlapping Sets of Tyrosine-based Sorting Signals

1998 • 253 citations

Atomic Structure of Clathrin

1998 • 224 citations

Pan1p, Yeast eps15, Functions as a Multivalent Adaptor That Coordinates Protein–Protein Interactions Essential for Endocytosis

1998 • 220 citations

Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant μ2 subunit and its effects on endocytosis

1999 • 212 citations

Arrestin/Clathrin Interaction

1997 • 209 citations

A Clathrin-binding Site in the Hinge of the β2 Chain of Mammalian AP-2 Complexes

1995 • 197 citations

Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis

1999 • 196 citations

On the structure of coated vesicles

1976 • 195 citations

Crystal structure of the α appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly

1999 • 180 citations

Inhibition of receptor-mediated endocytosis by the amphiphysin SH3 domain

1997 • 179 citations

Peptide–Surface Association: The Case of PDZ and PTB Domains

1996 • 178 citations

Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation

1998 • 167 citations

Crystal Structure of the VHS and FYVE Tandem Domains of Hrs, a Protein Involved in Membrane Trafficking and Signal Transduction

2000 • 164 citations

Deep-etch visualization of proteins involved in clathrin assembly.

1988 • 163 citations

Pan1p, End3p, and Sla1p, Three Yeast Proteins Required for Normal Cortical Actin Cytoskeleton Organization, Associate with Each Other and Play Essential Roles in Cell Wall Morphogenesis

2000 • 159 citations

Epsin 1 Undergoes Nucleocytosolic Shuttling and Its Eps15 Interactor Nh2-Terminal Homology (Enth) Domain, Structurally Similar to Armadillo and Heat Repeats, Interacts with the Transcription Factor Promyelocytic Leukemia Zn2+ Finger Protein (Plzf)

2000 • 158 citations

Clathrin self-assembly is mediated by a tandemly repeated superhelix

1999 • 147 citations

Identification and Characterization of a Novel Protein Interacting with Ral-binding Protein 1, a Putative Effector Protein of Ral

1998 • 143 citations

Clathrin coats at 21Aresolution: a cellular assembly designed to recycle multiple membrane receptors

1998 • 142 citations

γ-Synergin

1999 • 140 citations

Structure and Asn-Pro-Phe Binding Pocket of the Eps15 Homology Domain

1998 • 122 citations

AP180 and AP-2 Interact Directly in a Complex That Cooperatively Assembles Clathrin

1999 • 121 citations

Crystal structure of the pleckstrin homology domain from dynamin

1994 • 120 citations

The EH Network

1999 • 118 citations

Clathrin coat construction in endocytosis

2000 • 116 citations

Functional Organization of Clathrin in Coats

1999 • 114 citations

Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery

1999 • 112 citations

Eps15 Is Recruited to the Plasma Membrane upon Epidermal Growth Factor Receptor Activation and Localizes to Components of the Endocytic Pathway during Receptor Internalization

1999 • 110 citations

Mapping of Eps15 Domains Involved in Its Targeting to Clathrin-coated Pits

2000 • 107 citations

Coat Proteins Regulating Membrane Traffic

1999 • 95 citations

Parallel Dimers and Anti-parallel Tetramers Formed by Epidermal Growth Factor Receptor Pathway Substrate Clone 15 (EPS15)

1997 • 76 citations

Deep-etch visualization of 27S clathrin: a tetrahedral tetramer.

1987 • 56 citations

The EH1 Domain of Eps15 Is Structurally Classified as a Member of the S100 Subclass of EF-Hand-Containing Proteins

1999 • 33 citations

Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1)

1999 • 31 citations