Effects of lipid peroxides on prostacyclin and thromboxane generation in hypercholesterolemic rabbits

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

1976 • 956 citations

A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation

1976 • 606 citations

STUDIES ON THE ROLE OF LIPOPEROXIDES IN HUMAN PATHOLOGY

1952 • 347 citations

Free radicals in biology and medicine

1985 • 346 citations

Bovine endothelial cells in culture produce thromboxane as well as prostacyclin.

1981 • 300 citations

THE PROSTACYCLIN-THROMBOXANE A2 BALANCE: PATHOPHYSIOLOGICAL AND THERAPEUTIC IMPLICATIONS

1983 • 283 citations

Prostacyclin and thromboxane A2 biosynthesis capacities of heart, arteries and platelets at various stages of experimental atherosclerosis in rabbits

1978 • 256 citations

Enzymatic conversion of prostaglandin endoperoxide H2 and arachidonic acid to prostacyclin by cultured human endothelial cells.

1978 • 196 citations

LIPID PEROXIDATION IN RELATION TO PROSTACYCLIN AND THROMBOXANE PHYSIOLOGY AND PATHOPHYSIOLOGY

1983 • 184 citations

INHIBITION OF CYCLO-OXYGENASE AND LIPOXYGENASE

1983 • 158 citations

Dietary Supplementation with Vitamin E in Hyperlipoproteinemias: Effects on Plasma Lipid Peroxides, Antioxidant Activity, Prostacyclin Generation and Platelet Aggregability

1985 • 121 citations

Prostacyclin and thromboxane A2 synthesis by rabbit pulmonary artery.

1980 • 117 citations

Prostacyclin production by cultured smooth muscle cells from atherosclerotic rabbit aorta

1980 • 96 citations

Platelet membrane fluidity and aggregation of rabbit platelets

1984 • 46 citations

Maintenance of the tone of the human umbilical artery by prostaglandin and thromboxane formation.

1976 • 36 citations

Increased thromboxane B₂ biosynthesis in platelets

1982 • 29 citations

Effect of ethanol on prostacyclin and thromboxane A2 synthesis in rat aortic rings

1985 • 26 citations

Plasma lipid peroxidation in hyperlipidemic chickens

1985 • 16 citations

[Study of lipid peroxidation by the assay of malondialdehyde in human and experimental atheroma].

1986 • 13 citations

Platelets, Endothelium and Vessel Injury

1985 • 12 citations

Advances in Hemostasis and Thrombosis

1985 • 4 citations

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