Evidence for the Involvement of Retinoic Acid Receptor RARα-dependent Signaling Pathway in the Induction of Tissue Transglutaminase and Apoptosis by Retinoids

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

Identification of a second human retinoic acid receptor

1988 • 1,049 citations

Transglutaminases

1980 • 818 citations

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

1991 • 672 citations

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

1992 • 583 citations

G _h : a GTP-Binding Protein with Transglutaminase Activity and Receptor Signaling Function

1994 • 550 citations

Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde 3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle

1983 • 486 citations

Keratinocyte-specific transglutaminase of cultured human epidermal cells: Relation to cross-linked envelope formation and terminal differentiation

1985 • 479 citations

Induction and activation of tissue transglutaminase during programmed cell death

1987 • 467 citations

HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis

1990 • 390 citations

Inhibition of nuclear hormone receptor activity by calreticulin

1994 • 372 citations

Retinoids Selective for Retinoid X Receptor Response Pathways

1992 • 342 citations

Carotenoids up-regulate connexin43 gene expression independent of their provitamin A or antioxidant properties.

1992 • 330 citations

Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells.

1993 • 290 citations

A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects.

1992 • 256 citations

Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants.

1993 • 193 citations

Amino acid sequence of guinea pig liver transglutaminase from its cDNA sequence

1988 • 181 citations

Interaction between retinoic acid and vitamin D signaling pathways.

1993 • 171 citations

Retinoids in Normal Development and Teratogenesis

1992 • 170 citations

Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells.

1985 • 161 citations

A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line.

1992 • 160 citations

Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids.

1992 • 158 citations

The Conserved Ninth C-Terminal Heptad in Thyroid Hormone and Retinoic Acid Receptors Mediates Diverse Responses by Affecting Heterodimer but Not Homodimer Formation

1993 • 132 citations

The molecular basis of retinoic acid action. Transcriptional regulation of tissue transglutaminase gene expression in macrophages.

1988 • 128 citations

Apoptosis II: The Molecular Basis of Apoptosis in Disease

1994 • 126 citations

A Transglutaminase That Converts Interleukin-2 into a Factor Cytotoxic to Oligodendrocytes

1993 • 125 citations

Phenotype‐specific “tissue” transglutaminase regulation in human neuroblastoma cells in response to retinoic acid: Correlation with cell death by apoptosis

1992 • 119 citations

Regulation of type I (epidermal) transglutaminase mRNA levels during squamous differentiation: down regulation by retinoids.

1989 • 119 citations

Primary structure of keratinocyte transglutaminase.

1990 • 118 citations

Differential regulation by retinoic acid and calcium of transglutaminases in cultured neoplastic and normal human keratinocytes.

1986 • 115 citations

Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cells

1991 • 114 citations

Identification of retinoids with nuclear receptor subtype-selective activities.

1991 • 105 citations

Regulation of transglutaminase type II by transforming growth factor-beta 1 in normal and transformed human epidermal keratinocytes.

1990 • 95 citations

Retinoic acid induces transglutaminase activity but inhibits cornification of cultured epidermal cells.

1982 • 93 citations

Apoptosis II The molecular basis of apoptosis in disease

1995 • 92 citations

Selective Synthetic Ligands for Human Nuclear Retinoic Acid Receptors

1992 • 84 citations

Multiple cell cycle access to the apoptotic death programme in human neuroblastoma cells

1993 • 82 citations

A Monoclonal Antibody to Cellular Transglutaminase

1985 • 65 citations

Retinoids: From basic science to clinical applications

1995 • 57 citations

Retinoids increase transglutaminase activity and inhibit ornithine decarboxylase activity in Chinese hamster ovary cells and in melanoma cells stimulated to differentiate.

1982 • 54 citations

Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor alpha.

1994 • 52 citations

Induction of tissue transglutaminase and apoptosis by retinoic acid in the limb bud

1992 • 50 citations

Characterization of the transglutaminase-mediated large molecular weight polymer from rat liver; its relationship to apoptosis.

1993 • 43 citations

Regulation of apoptosis by low serum in cells of different stages of neoplastic progression: enhanced susceptibility after loss of a senescence gene and decreased susceptibility after loss of a tumor suppressor gene.

1994 • 42 citations

An involucrin-like protein in hepatocytes serves as a substrate for tissue transglutaminase during apoptosis.

1992 • 35 citations

Regulation of Type I and Type II Transglutaminase in Normal Human Bronchial Epithelial and Lung Carcinoma Cells

1992 • 35 citations

Involvement of retinoic acid nuclear receptors in retinoic acid-induced tissue transglutaminase gene expression in rat tracheal 2C5 cells

1991 • 17 citations