Induction of tissue transglutaminase and apoptosis by retinoic acid in the limb bud

A formaldehyde - glutaraldehyde fixative of high osmolarity for use in electron microscopy

1965 • 5,954 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Apoptosis: Mechanisms and Roles in Pathology

1991 • 1,368 citations

CELL DEATHS IN NORMAL VERTEBRATE ONTOGENY

1951 • 1,194 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

Death in Embryonic Systems

1966 • 943 citations

Retinoic acid causes an anteroposterior transformation in the developing central nervous system

1989 • 885 citations

Transglutaminases

1980 • 818 citations

The morphology of various types of cell death in prenatal tissues

1973 • 716 citations

Terminal differentiation of cultured human epidermal cells

1977 • 521 citations

Apoptosis-the molecular basis of cell death

1992 • 517 citations

Morphogenesis of malformations in hamsters caused by retinoic acid: Relation to dose and stage at treatment

1972 • 501 citations

Induction and activation of tissue transglutaminase during programmed cell death

1987 • 467 citations

Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development

1991 • 410 citations

Teratogens and craniofacial malformations: relationships to cell death

1988 • 397 citations

Expression of the homeobox Hox-4 genes and the specification of position in chick wing development

1991 • 394 citations

Vitamin A congeners

1986 • 369 citations

Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid

1973 • 287 citations

The molecular and cellular basis of affinity maturation in the antibody response

1992 • 278 citations

Developmental analysis of the retinoic acid-inducible RAR-βJ2 promoter in transgenic animals

1991 • 258 citations

Isolation of 3,4-didehydroretinoic acid, a novel morphogenetic signal in the chick wing bud

1990 • 252 citations

Retinoids and vertebrate limb pattern formation

1989 • 251 citations

Effects of retinoic acid excess on expression of Hox-2.9 and Krox-20 and on morphological segmentation in the hindbrain of mouse embryos.

1991 • 247 citations

Hormone-induced cell death. Purification ad properties of thymocytes undergoing apoptosis after glucocorticoid treatment.

1982 • 244 citations

TERATOGENIC ACTIVITY OF RETINOIC ACID

1967 • 233 citations

Enzymatic conversion of β-carotene into β-apo-carotenals and retinoids by human, monkey, ferret, and rat tissues

1991 • 233 citations

Involvement of the Chox-4 chicken homeobox genes in determination of anteroposterior axial polarity during limb development

1991 • 223 citations

The expression of "tissue" transglutaminase in two human cancer cell lines is related with the programmed cell death (apoptosis).

1991 • 183 citations

Isotretinoin embryopathy and the cranial neural crest: an in vivo and in vitro study.

1986 • 170 citations

Drawings of British Plants, Being Illustrations of the Species of Flowering Plants Growing Naturally in the British Isles. Parts I-III: Ranunculaceae to Cruciferae.Stella Ross-Craig

1951 • 154 citations

A transgene insertional mutation at an imprinted locus in the mouse genome

1990 • 147 citations

The molecular basis of retinoic acid action. Transcriptional regulation of tissue transglutaminase gene expression in macrophages.

1988 • 128 citations

Retinoic acid-induced spina bifida: evidence for a pathogenetic mechanism

1990 • 120 citations

Physiological occurrence, biosynthesis and metabolism of retinoic acid: evidence for roles of Cellular Retinol-Binding Protein (CRBP) and Cellular Retinoic Acid-Binding Protein (CRABP) in the pathway of retinoic acid homeostasis

1991 • 120 citations

Elevations in the endogenous levels of the putative morphogen retinoic acid in embryonic mouse limb-buds associated with limb dysmorphogenesis

1989 • 117 citations

Excess vitamin A and development of the cerebral cortex

1967 • 101 citations

In vitro analysis of the control of cell death in a zone of prospective necrosis from the chick wing bud

1968 • 100 citations

Programmed Cell Death: New Thoughts and Relevance to Aging

1990 • 90 citations

Limb reduction defects in humans associated with prenatal isotretinoin exposure

1991 • 61 citations

Studies of vitamin A‐induced teratogenesis: Effects on embryonic mesenchyme and epithelium, and on incorporation of H³‐thymidine

1968 • 58 citations

Morphogenesis and malformation of the limb

1978 • 57 citations

Retinoids increase transglutaminase activity and inhibit ornithine decarboxylase activity in Chinese hamster ovary cells and in melanoma cells stimulated to differentiate.

1982 • 54 citations

Correlation between transglutaminase activity and polyamine levels in human neuroblastoma cells *1Effect of retinoic acid and ?-difluoromethylornithine

1988 • 45 citations

Ornithine decarboxylase, transglutaminase, diamine oxidase and total diamines and polyamines in maternal liver and kidney throughout rat pregnancy

1986 • 43 citations

Ectodermal and mesodermal cell death patterns in 6‐mercaptopurine riboside‐induced digital deformities

1980 • 38 citations

Teratogenicity of the Retinoids

2015 • 17 citations

The biochemical pathology of toxic cell death.

1985 • 15 citations

Limb development in mouse embryos. III. Cellular events underlying the determination of altered skeletal patterns following treatment with 5′fluoro-2-deoxyuridine

1981 • 14 citations

Characteristics of Cyclic AMP Enhancement of Retinoic Acid Induction of Increased Transglutaminase Activity in HL60 Cells

1988 • 9 citations

Metabolic Disposition and Development of New Chemopreventive Retinoids

1991 • 7 citations