Acquired Haemophilia: Review and Meta‐Analysis Focused on Therapy and Prognostic Factors

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Regression Models and Life-Tables

1992 • 27,454 citations

Regression Models and Life-Tables

1972 • 27,145 citations

A Cell-based Model of Hemostasis

2001 • 1,445 citations

A Survey of 215 Non-Hemophilic Patients with Inhibitors to Factor VIII

1981 • 773 citations

The Nijmegen Modification of the Bethesda Assay for Factor VIII:C Inhibitors: Improved Specificity and Reliability

1995 • 640 citations

1-DEAMINO-8-D-ARGININE VASOPRESSIN: A NEW PHARMACOLOGICAL APPROACH TO THE MANAGEMENT OF HAEMOPHILIA AND VON WILLEBRAND'S DISEASE

1977 • 597 citations

Platelet activity of high‐dose factor VIIa is independent of tissue factor

1997 • 544 citations

A More Uniform Measurement of Factor VIII Inhibitors

1975 • 498 citations

ANTI-IDIOTYPIC SUPPRESSION OF AUTOANTIBODIES TO FACTOR VIII (ANTIHAEMOPHILIC FACTOR) BY HIGH-DOSE INTRAVENOUS GAMMAGLOBULIN

1984 • 485 citations

Biochemistry and Physiology of Blood Coagulation

1999 • 459 citations

DIABETIC KETOACIDOSIS

1974 • 363 citations

Home Treatment of Mild to Moderate Bleeding Episodes Using Recombinant Factor VIIa (Novoseven) in Haemophiliacs with Inhibitors

1998 • 362 citations

Frapper fort ou doucement:A Gramnegative dilemma.

1978 • 358 citations

The Treatment of Bleeding in Acquired Haemophilia with Recombinant Factor VIIa: A Multicentre Study

1997 • 356 citations

A More Uniform Measurement of Factor VIII Inhibitors

1975 • 316 citations

Multicenter Retrospective Study on the Utilization of FEIBA in France in Patients with Factor VIII and Factor IX Inhibitors

1997 • 287 citations

Efficacy of Prothrombin-Complex Concentrates in Hemophiliacs with Antibodies to Factor VIII

1980 • 257 citations

Pharmacokinetics and pharmacodynamics of recombinant factor VIIa

1994 • 256 citations

Use of porcine factor VIII in the treatment of patients with acquired hemophilia

1993 • 253 citations

Activated factor VII activates factors IX and X on the surface of activated platelets: thoughts on the mechanism of action of high-dose activated factor VII.

1998 • 244 citations

A Prospective, Randomized Trial of Prednisone and Cyclophosphamide in the Treatment of Patients with Factor VIII Autoantibodies

1993 • 241 citations

Safety of factor VIII inhibitor bypass activity (FEIBA^®): 10‐year compilation of thrombotic adverse events

2002 • 218 citations

Acquired hemophilia. A natural history study of 16 patients with factor VIII inhibitors receiving little or no therapy

1987 • 218 citations

9 Acquired inhibitors

1996 • 186 citations

The use of factor eight inhibitor by-passing activity (FEIBA immuno) product for treatment of bleeding episodes in hemophiliacs with inhibitors

1983 • 182 citations

A prospective study of treatment of acquired (autoimmune) factor VIII inhibitors with high-dose intravenous gammaglobulin

1995 • 171 citations

Activated Prothrombin Concentrate for Patients with Factor VIII Inhibitors

1974 • 163 citations

Acquired Hemophilia

1987 • 162 citations

Acquired hemophilia due to factor VIII inhibitors in 34 patients

1998 • 162 citations

1 Acquired haemophilia

1998 • 155 citations

Inhibitors against factor VIII in patients with cancer

2001 • 146 citations

Recombinant factor VIIa for patients with inhibitors to factor VIII or IX or factor VII deficiency

1999 • 146 citations

Post-partum factor VIII inhibitors. A review of the literature with special reference to the value of steroid and immunosuppressive treatment.

1995 • 136 citations

Inhibition of thrombin generation by the zymogen factor VII: implications for the treatment of hemophilia A by factor VIIa

2000 • 131 citations

Combination Immunosuppressive Therapy after Factor VIII Infusion for Acquired Factor VIII Inhibitor

1989 • 128 citations

A<scp>CQUIRED</scp> H<scp>EMOPHILIA</scp>

2001 • 124 citations

Post-Partum Factor VIII Inhibitors

1995 • 117 citations

Relationship between Factor VII Activity and Clinical Efficacy of Recombinant Factor VIIa Given by Continuous Infusion to Patients with Factor VIII Inhibitors

2001 • 115 citations

Acute Myocardial Infarction Following Administration of Recombinant Activated Factor VII (Novo Seven) in a Patient with Haemophilia A and Inhibitor

1999 • 113 citations

Treatment of coagulation inhibitors with extracorporeal immunoadsorption (Ig‐Therasorb)

2001 • 109 citations

Drug therapy

1995 • 106 citations

A possible mechanism of action of activated factor VII independent of tissue factor.

1998 • 106 citations

Corticosteroid Therapy for Acquired F VIII:C Inhibitors

1981 • 105 citations

Recombinant factor VIIa (NovoSeven®) and the safety of treatment

2001 • 104 citations

ACQUIRED HAEMOPHILIA AND ITS MANAGEMENT

1995 • 98 citations

Suppression of an Antibody to Factor VIII by a Combination of Factor VIII and Cyclophosphamide

1971 • 97 citations

Immune tolerance induction in hemophilia patients with inhibitors: costly can be cheaper

2000 • 95 citations

Successful Treatment of Acquired Hemophilia with Oral Immunosuppressive Therapy

1997 • 93 citations

Treatment of Patients with Factor VIII and Factor IX Inhibitors with Special Focus on the Use of Recombinant Factor VIIa

1999 • 92 citations

Safety Profile of Porcine Factor VIII and Its Use as Hospital and Home-Therapy for Patients with Haemophilia-A and Inhibitors: the Results of An International Survey

1996 • 89 citations

Postpartum acquired factor VIII inhibitors: Results of a survey

1998 • 83 citations

Normal pregnancy in a patient with a prior postpartum factor VIII inhibitor: with observations on pathogenesis and prognosis

1981 • 83 citations

Dosing and Monitoring NovoSeven® Treatment

1996 • 81 citations

Elective Surgery on Factor VIII Inhibitor Patients Using Continuous Infusion of Recombinant Activated Factor VII

2001 • 81 citations

Treatment of Anti-Factor VIII Antibodies

1977 • 80 citations

Acquired factor VIII inhibitors in nonhemophilic patients

1997 • 77 citations

DDAVP in acquired hemophilia a: Case report and review of the literature

1993 • 76 citations

Recombinant Factor VIla (NovoSeven®) in the Treatment of Internal Bleeding in Patients with Factor VIM and IX Inhibitors

1996 • 75 citations

Use of Porcine Factor VIII in the Management of Seventeen Patients with Factor VIII Antibodies

1984 • 75 citations

New protocol for immune tolerance induction in acquired hemophilia.

2000 • 75 citations

Acquired Hemophilia in Patients With Hematologic Malignancies

2000 • 70 citations

Experiences with continuous infusion of recombinant activated factor VII.

1998 • 70 citations

The Role of Intensive Plasma Exchange in the Prevention and Management of Haemorrhage in Patients with Inhibitors to Factor VIII

1981 • 70 citations

A survey of patients with acquired haemophilia in a haemophilia centre over a 28-year period

2000 • 69 citations

Acquired Hemophilia A in Women Postpartum: Clinical Manifestations, Diagnosis, and Treatment

2000 • 67 citations

Solid Tumors and Factor VIII Antibodies

1999 • 67 citations

Factor Xa and Prothrombin: Mechanism of Action of FEIBA

1999 • 63 citations

Acquired inhibitors in malignant and nonmalignant disease states

1991 • 61 citations

Use of prothrombin complex concentrates in management of bleeding in hemophiliacs with inhibitors--benefits and limitations.

1994 • 59 citations

Treatment of haemophilia in the United Kingdom 1981-1996

2001 • 59 citations

Cyclosporine Therapy for Acquired Factor VIII Inhibitor in a Patient with Systemic Lupus Erythematosus

1996 • 58 citations

Acquired Haemophilia – a study of ten cases

2000 • 56 citations

Overall experience with NovoSeven®

2000 • 54 citations

Effect of frequent factor VIII replacement on the level of factor VIII antibodies in haemophiliacs

1982 • 53 citations

Acquired haemophilia A in women postpartum: management of bleeding episodes and natural history of the factor VIII inhibitor

1997 • 53 citations

Adverse Effects of Treatment with Porcine Factor VIII

1991 • 51 citations

Acquired haemophilia: experiences with a standardized approach

2001 • 47 citations

Acquired haemophilia in association with organ‐specific autoimmune disease

2001 • 44 citations

Combined prednisolone and intravenous immunoglobulin treatment for acquired factor VIII inhibitors: a 2‐year review

2001 • 43 citations

Postpartum Acquired Hemophilia (Factor VIII Inhibitors): A Case Report and Review of the Literature

2000 • 42 citations

Production of thromboxane and prostaglandins in human blood in the presence of thromboxane synthase inhibitors

1991 • 42 citations

Elevated levels of homocysteine increase IL-6 production in monocytic Mono Mac 6 cells

2000 • 41 citations

Low response to high‐dose intravenous immunoglobulin in the treatment of acquired factor VIII inhibitor

1996 • 41 citations

The effect of 1‐deamino 8 D‐arginine vasopressin (DDAVP) in a nonhaemophilic patient with an acquired type II factor VIII inhibitor

1985 • 38 citations

Autoimmune factor VIII inhibitors

1999 • 37 citations

Treatment of haemophilia in the United Kingdom 1981–1996

2001 • 37 citations

Aquired factor VIII inhibitor treated with cyclophosphamide, vincristine, and prednisone

2002 • 36 citations

Management of haemophilia in patients with high‐titre inhibitors: focus on the evolution of activated prothrombin complex concentrate AUTOPLEX® T

1999 • 35 citations

Successful treatment of acquired factor VIII inhibitors with cyclosporin

1998 • 35 citations

Antibodies against Factor VIII in Patients with Solid Tumors: Successful Treatment of Cancer May Suppress Inhibitor Formation

1998 • 34 citations

Cloning of the bovine activin receptor type II gene (ACVR2) and mapping to chromosome 2 (BTA2)

1996 • 33 citations

Acquired haemophilia: experience of two Italian centres with 17 new cases

1997 • 33 citations

Graves' disease and autoimmune factor VIII deficiency.

1996 • 32 citations

Cyclosporine treatment of acquired hemophilia due to factor VIII antibodies.

2000 • 32 citations

Von Willebrand factor contaminating porcine factor VIII concentrate (Hyate: C) causes platelet aggregation

1986 • 31 citations

Comparison of the factor VII:C clot analysis and a modified activated factor VII analysis for monitoring factor VII activity in patients treated with recombinant activated factor VII (NovoSeven®)

2000 • 31 citations

Protein A sepharose immunoadsorption: immunological and haemostatic effects in two cases of acquired haemophilia

2001 • 30 citations

Acquired factor VIII inhibitors?successful treatment with an oral outpatient regimen

1999 • 29 citations

Immune tolerance induction in hemophilia patients with inhibitors: costly can be cheaper

2000 • 29 citations

Spontaneous inhibitors of factor VIII: Kinetics of inactivation of human and porcine factor VIII

1999 • 28 citations

Acquired haemophilia in the elderly is a severe disease: report of five new cases

2001 • 28 citations

Successful treatment of a non‐haemophilic patient with inhibitor to factor VIII by double‐filtration plasmapheresis

1999 • 25 citations

Acquired factor VIII autoantibody inhibitors: current concepts and potential therapeutic strategies for the future.

2000 • 24 citations

Porcine factor VIII: preparation and use in treatment of inhibitor patients.

1984 • 24 citations

Acquired haemophilia complicating the remission of a patient with high grade non-Hodgkin's lymphoma treated by fludarabine

2000 • 23 citations

Acquired Factor VIII Inhibitor Associated with Multiple Sclerosis, Successfully Treated with Porcine Factor VIII

1987 • 22 citations

Porcine factor VIII: current status and future developments

2002 • 21 citations

Measurement of Active Coagulation Factors in Autoplex®-T with Colorimetric Active Site-Specific Assay Technology

1998 • 21 citations

Measurement of active coagulation factors in Autoplex-T with colorimetric active site-specific assay technology.

1998 • 19 citations

The Use of Agents that By&amp;ndash;Pass Factor VIII Inhibitors in Patients with Haemophilia

1999 • 18 citations

Continuous infusion of porcine factor VIII in patients with haemophilia A and high‐responding inhibitors: stability and clinical experience

2001 • 17 citations

Plasma Exchange for Acquired Hemophilia: A Case Report

1999 • 15 citations

Inhibitor to factor VIII in a non-haemophilic patient: evaluation of the response to DDAVP and the in vitro kinetics of factor VIII. A case report.

1987 • 15 citations

Acquired haemophilia in the elderly is a severe disease: report of five new cases

2001 • 14 citations

Acquired haemophilia in South Australia: a case series

2001 • 14 citations

Continuous Infusion of Recombinant Factor VIIa: Continue or not?

2001 • 13 citations

A Case of Factor VIII Inhibitor‐Positive Acquired Hemophilia Treated by Plasmapheresis

1999 • 12 citations

Prednisone and low‐dose activated prothrombin complex concentrates for FVIII inhibitor in nonhaemophilic patients

1998 • 12 citations

A Randomized Study of Factor VIII or Prothrombin Complex Concentrate Infusions in Children with Haemophilia and Antibodies to Factor VIII

1979 • 10 citations

Reduction of Acquired High Titer Factor VIII Antibodies by Extracorporeal Antibody-based Immunoadsorption without Additional Immunosuppressive Therapy

1998 • 6 citations

Continuous infusion of porcine factor VIII: stability, microbiological safety and clinical experience

2002 • 5 citations

Disappearance of factor VIII autoantibodies preceding autoimmune haemolytic anaemia

2000 • 3 citations