Putamen Mitochondrial Energy Metabolism Is Highly Correlated to Emotional and Intellectual Impairment in Schizophrenics

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1951 • 319,299 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry

1979 • 1,883 citations

Cytochrome oxidase: an endogenous metabolic marker for neuronal activity

1989 • 1,231 citations

Abnormalities of the Left Temporal Lobe and Thought Disorder in Schizophrenia

1992 • 1,173 citations

Neuropsychological Function in Schizophrenia

1991 • 1,158 citations

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1990 • 1,102 citations

The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones

1990 • 1,021 citations

Antischizophrenic Drugs: Chronic Treatment Elevates Dopamine Receptor Binding in Brain

1977 • 1,017 citations

Characterization of PicoGreen Reagent and Development of a Fluorescence-Based Solution Assay for Double-Stranded DNA Quantitation

1997 • 752 citations

Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET

1997 • 707 citations

Schizophrenia and cognitive dysmetria: a positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry.

1996 • 618 citations

Hypofrontality in schizophrenia: distributed dysfunctional circuits in neuroleptic-naïve patients

1997 • 593 citations

Cerebral Glucography With Positron Tomography

1982 • 538 citations

Linking Mind and Brain in the Study of Mental Illnesses: A Project for a Scientific Psychopathology

1997 • 445 citations

Fluorometric quantification of DNA in cells and tissue

1983 • 445 citations

DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water

1990 • 395 citations

Increased Brain Dopamine and Dopamine Receptors in Schizophrenia

1982 • 393 citations

Frontostriatal Disorder of Cerebral Metabolism in Never-Medicated Schizophrenics

1992 • 330 citations

Studies on Cytochrome Oxidase

1965 • 328 citations

Sensory and cognitive functions of the basal ganglia

1997 • 284 citations

Differential Activation of the Caudate Nucleus in Primates Performing Spatial and Nonspatial Working Memory Tasks

1997 • 283 citations

Effect of impulse blockage on cytochrome oxidase activity in monkey visual system

1984 • 239 citations

Functional sites of neuroleptic drug action in the human brain: PET/FDG studies with and without haloperidol

1996 • 236 citations

Cortical-striatal-thalamic circuits and brain glucose metabolic activity in 70 unmedicated male schizophrenic patients

1993 • 206 citations

The Effect of Neuroleptics on Cognitive and Psychomotor Function

1990 • 191 citations

Neurotransmitter aberrations in schizophrenia: New perspectives and therapeutic implications

1997 • 187 citations

Positron Emission Tomography in Schizophrenic Patients with and without Neuroleptic Medication

1985 • 177 citations

Correlation of positive symptoms exclusively to hyperperfusion or hypoperfusion of cerebral cortex in never-treated schizophrenics

1997 • 171 citations

Dorsal Striatal Size, Shape, and Metabolic Rate in Never-Medicated and Previously Medicated Schizophrenics Performing a Verbal Learning Task

1998 • 158 citations

Decreased Cytochrome-c Oxidase Activity and Lack of Age-Related Accumulation of Mitochondrial DNA Deletions in the Brains of Schizophrenics

1995 • 153 citations

Studies on Cytochrome Oxidase

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Prevalence of dementia disorders in institutionalized Swedish old people THE WORK LOAD IMPOSED BY CARING FOR THESE PATIENTS

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Cognitive function in schizophrenia

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NMDA receptor mRNA correlation with antemortem cognitive impairment in schizophrenia

1996 • 100 citations

Coordination of ATP production and consumption in brain: Parallel regulation of cytochrome oxidase and Na+, K+-ATPase

1992 • 95 citations

Mitochondrial Function is Differentially Altered in the Basal Ganglia of Chronic Schizophrenics

1999 • 93 citations

Motor and mental aspects of extrapyramidal syndromes

1995 • 81 citations

Neuroleptic-induced mitochondrial enzyme alterations in the rat brain.

1997 • 80 citations

Temporal Lobe Metabolic Differences in Medication-Free Outpatients with Schizophrenia via the PET-600

1996 • 54 citations

Studies on Cytochrome Oxidase

1966 • 52 citations

Association between Striatal Reduction and Poor Wisconsin Card Sorting Test Performance in Patients with Schizophrenia

1997 • 50 citations

Striatal synaptophysin expression and haloperidol-induced synaptic plasticity

1994 • 40 citations

Normalization of cytochrome-c oxidase activity in the rat brain by neuroleptics after chronic treatment with PCP or methamphetamine

1997 • 34 citations

Kinetic evidence for isomerization of the dopamine receptor-raclopride complex

1996 • 33 citations

A histochemical demonstration of altered cytochrome oxidase activity in the rat brain by neuroleptics

1998 • 31 citations

Instrumental assessment of psychomotor functions and the effects of psychotropic drugs

1994 • 24 citations

Motor and mental aspects of extrapyramidal syndromes

1995 • 13 citations