An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice

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1983 • 301 citations

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1990 • 238 citations

Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication

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1981 • 203 citations

Acute and chronic ethanol increases reactive oxygen species generation and decreases viability in fresh, isolated rat hepatocytes

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1990 • 169 citations

Analysis of DNA damage and repair in murine leukemia L1210 cells using a quantitative polymerase chain reaction assay

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1990 • 155 citations

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Multiple hepatic mitochondrial DNA deletions suggest premature oxidative aging in alcoholic patients

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Increased Oxidative Damage to Mitochondrial DNA Following Chronic Ethanol Consumption

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Diterpenoids from germander, an herbal medicine, induce apoptosis in isolated rat hepatocytes

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Premature oxidative aging of hepatic mitochondrial DNA in Wilson's disease

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1995 • 105 citations

Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications

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Increased ethane exhalation, an in vivo index of lipid peroxidation, in alcohol-abusers.

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Rapid isolation of animal mitochondrial DNA by alkaline extraction

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Oxidation of Mitochondrial Proteins and DNA Following Administration of Ethanol

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Template integrity is essential for PCR amplification of 20- to 30-kb sequences from genomic DNA.

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Electrophoresis of DNA in agarose gels

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High proportions of mtDNA duplications in patients with Kearns-Sayre syndrome occur in the heart

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Oxidation of pyrazole by reconstituted systems containing cytochrome P-450 IIE1

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Expression of the cytochrome b-URF6-URF5 region of the mouse mitochondrial genome

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Generation of Reactive Oxygen Species and Reduction of Ferric Chelates by Microsomes in the Presence of a Reconstituted System Containing Ethanol, NAD⁺ and Alcohol Dehydrogenase

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The use of C₀t-1 probe DNA for the detection of low levels of DNA fragmentation

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