Paraquat toxicity and oxidative damage

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Methods of enzymatic analysis

1985 • 3,497 citations

Melatonin : a potent, endogenous hydroxyl radical scavenger

1993 • 1,673 citations

A review of the evidence supporting melatonin's role as an antioxidant

1995 • 827 citations

Melatonin: A peroxyl radical scavenger more effective than vitamin E

1994 • 741 citations

Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity

1974 • 540 citations

Bipyridylium quaternary salts and related compounds. V. Pulse radiolysis studies of the reaction of paraquat radical with oxygen. Implications for the mode of action of bipyridyl herbicides

1973 • 518 citations

Accidental Poisoning by Paraquat: Report of Two Cases in Man

1966 • 294 citations

Evidence for energy-dependent accumulation of paraquat into rat lung

1974 • 294 citations

Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats

1994 • 260 citations

High melatonin solubility in aqueous medium

1994 • 256 citations

Paraquat

1976 • 187 citations

Melatonin reduces kainate‐induced lipid peroxidation in homogenates of different brain regions

1995 • 157 citations

Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro

1995 • 149 citations

Oxygen species in paraquat toxicity: the crypto‐OH radical

1981 • 149 citations

Lipid peroxidation and antioxidant systems in the liver injury produced by glutathione depleting agents

1990 • 134 citations

Melatonin administration prevents lipopolysaccharide‐induced oxidative damage in phenobarbital‐treated animals

1995 • 127 citations

Glutathione: a vehicle for the transport of chemically reactive metabolites in vivo

1991 • 121 citations

Increase in hepatic mixed disulphide and glutathione disulphide levels elicited by paraquat

1982 • 118 citations

Relevance of NADPH depletion and mixed disulphide formation in rat lung to the mechanism of cell damage following paraquat administration

1982 • 101 citations

In vivo oxidation of reduced nicotinamide-adenine dinucleotide phosphate by paraquat and diquat in rat lung

1977 • 99 citations

Production of hydroxyl radicals from paraquat radicals and H₂O₂

1981 • 98 citations

The relevance of pentose phosphate pathway stimulation in rat lung to the mechanism of paraquat toxicity

1976 • 95 citations

Melatonin, a mediator of electron transfer and repair reactions, acts synergistically with the chain-breaking antioxidants ascorbate, trolox and glutathione

1995 • 81 citations

Melatonin reduces H₂O₂‐induced lipid peroxidation in homogenates of different rat brain regions

1995 • 74 citations

Formation of hydroxyl radicals from the paraquat radical cation, demonstrated by a highly specific gas chromatographic technique. The role of superoxide radical anion, hydrogen peroxide, and glutathione reductase

1982 • 65 citations

Dissociation of microsomal oxygen reduction and lipid peroxidation with the electron acceptors, paraquat and menadione

1979 • 64 citations

Role of lipid peroxidation and DNA damage in paraquat toxicity and the interaction of paraquat with ionizing radiation

1992 • 53 citations

Acceleration of Lipid Peroxidation in Human Paraquat Poisoning

1981 • 52 citations

Effect of preinduction of metallothionein on paraquat toxicity in mice

1992 • 45 citations

Production of Limbic Motor Seizures and Brain Damage by Systemic and Intracerebral Injections of Paraquat in Rats

1992 • 41 citations

The role of xanthine oxidase in paraquat intoxication

1991 • 40 citations

Mechanism of paraquat-stimulated lipid peroxidation in mouse brain and pulmonary microsomes

1991 • 26 citations

Enhanced lipid peroxidation is not necessary for induction of metallothionein-I by oxidative stress

1991 • 23 citations

Detection of Paraquat-lnduced in vivo Lipid Peroxidation by Gas Chromatography/Mass Spectrometry and High-Pressure Liquid Chromatography

1993 • 22 citations

Distribution of paraquat into the brain after its systemic injection in rats.

1992 • 21 citations

Fe2+-supported in vivo lipid peroxidation induced by compounds undergoing redox cycling

1985 • 17 citations

The Effect of Carbohydrate Sulfate Salts on the Absorption and Excretion of Paraquat in Rats.

1993 • 3 citations