Clonal deletion of thymocytes as a tumor escape mechanism

Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

1996 • 1,281 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Natural history of HLA expression during tumour development

1993 • 448 citations

Myeloma Proteins as Tumor-Specific Transplantation Antigens

1972 • 325 citations

Transfer of myeloma idiotype-specific immunity from an actively immunised marrow donor

1995 • 269 citations

EVIDENCE FOR A BLOOD-THYMUS BARRIER USING ELECTRON-OPAQUE TRACERS

1972 • 258 citations

Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression.

1983 • 251 citations

Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

1991 • 249 citations

Peripheral T cell tolerance as a tumor escape mechanism: deletion of CD4⁺ T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma

1996 • 165 citations

Naive idiotype-specific CD4+ T cells and immunosurveillance of B-cell tumors.

1994 • 145 citations

Loss of transporter in antigen processing 1 transport protein and major histocompatibility complex class I molecules in metastatic versus primary breast cancer.

1995 • 137 citations

Idiotypic DNA Vaccines Against B‐cell Lymphoma

1995 • 134 citations

Antigen presenting cells in the thymus that can negatively select MHC class II-restricted T cells recognizing a circulating self antigen

1997 • 109 citations

Clonal deletion of specific thymocytes by an immunoglobulin idiotype.

1993 • 100 citations

Antigen-presenting cells in the thymus that can negatively select MHC class II-restricted T cells recognizing a circulating self antigen.

1997 • 93 citations

Naive CD4⁺ T cells confer idiotype‐specific tumor resistance in the absence of antibodies

1995 • 86 citations

The Role of Idiotype-Specific, CD4+ T Cells in Tumor Resistance against Major Histocompatibility Complex Class II Molecule Negative Plasmacytoma Cells

1993 • 81 citations

The transcapsular route: a new way for (self-) antigens to by-pass the blood-thymus barrier?

1988 • 67 citations

Weak positive selection of transgenic T cell receptor‐bearing thymocytes: importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities

1992 • 65 citations

Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor

1996 • 54 citations

Tolerance and Ways to Break It

1993 • 40 citations