Gene therapy of murine teratocarcinoma: separate functions for insulin-like growth factors I and II in immunogenicity and differentiation.

Differentiated Rat Glial Cell Strain in Tissue Culture

1968 • 1,480 citations

Hybridization of nucleic acids immobilized on solid supports

1984 • 1,357 citations

Normal genetically mosaic mice produced from malignant teratocarcinoma cells.

1975 • 1,175 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Teratocarcinomas and Mammalian Embryogenesis

1980 • 767 citations

Treatment of Established Renal Cancer by Tumor Cells Engineered to Secrete Interleukin-4

1991 • 733 citations

Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro.

1975 • 710 citations

Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice

1983 • 699 citations

Treatment and Prevention of Rat Glioblastoma by Immunogenic C6 Cells Expressing Antisense Insulin-Like Growth Factor I RNA

1993 • 328 citations

Immunotherapy of malignancy by in vivo gene transfer into tumors.

1993 • 320 citations

Chapter 8: Teratocarcinoma: Model for A Developmental Concept of Cancer

1967 • 246 citations

Cell lines derived from teratocarcinomas.

1976 • 201 citations

Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I.

1992 • 180 citations

Experimental Teratoma

1974 • 169 citations

Immunohistochemical localization of the mouse stage-specific embryonic antigen 1 in human tissues and tumors.

1983 • 155 citations

Expression of insulin‐like growth factors I and II and their receptor mRNAs in primary human astrocytomas and meningiomas; in vivo studies using in situ hybridization and immunocytochemistry

1992 • 124 citations

Growth factors as transforming proteins

1989 • 122 citations

Insulin-like growth factor-1 receptors and insulin-like growth factor-1-like activity in human primary breast cancer

1989 • 119 citations

Histochemical localization of IGF-I and IGF-II mRNA in the rat between birth and adulthood

1988 • 102 citations

Insulinlike growth factor II expression and oval cell proliferation associated with hepatocarcinogenesis in woodchuck hepatitis virus carriers

1988 • 98 citations

Autocrine function for insulin-like growth factor I in human small cell lung cancer cell lines and fresh tumor cells

1991 • 97 citations

Evidence for autocrine production of IGF-1 in human thyroid adenomas

1989 • 77 citations

Analysis of insulin-like growth factor II (IGF-II) expression in neoplastic nodules and hepatocellular carcinomas of woodchucks utilizing in situ hybridization and imununocytochemistry

1991 • 65 citations

Use of an Epstein-Barr virus episomal replicon for anti-sense RNA-mediated gene inhibition in a human cytotoxic T-cell clone.

1988 • 55 citations

Developmentally regulated expression of insulin-like growth factors by differentiated murine teratocarcinomas and extraembryonic mesoderm

1986 • 49 citations

Simultaneous production of IGF‐I and EGF competing growth factors by HT‐29 human colon cancer line

1987 • 46 citations

Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta.

1988 • 41 citations

Detection of type 1 insulinlike growth factor (IGF) receptors in Wilms' tumors.

1988 • 41 citations

Production of insulin‐like growth factor‐II (MSA) by endoderm‐like cells derived from embryonal carcinoma cells: Possible mediator of embryonic cell growth

1985 • 39 citations

Insulin and insulin-like growth factors in central nervous system tumors

1992 • 34 citations

Identification and characterization of polypeptide growth factors secreted by murine embryonal carcinoma cells

1989 • 33 citations

Teratocarcinoma stem cells.

1990 • 31 citations

Expression of insulin‐like growth factor 1 in sarcomas

1990 • 23 citations

Muscle differentiation: insulin-like growth factors as positive modulators of myogenic regulatory genes?

1993 • 15 citations

Secretion of polypeptides related to epidermal growth factor and insulinlike growth factor I by a human teratocarcinoma cell line

1991 • 6 citations