Recent advances in the characterization of epithelial ionic channels

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Ionic channels of excitable membranes

1985 • 7,199 citations

Random Data-Analysis and Measurement Procedures

1989 • 6,467 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Random Data: Analysis and Measurement Procedures

1975 • 2,157 citations

Ionic Blockage of Sodium Channels in Nerve

1973 • 1,590 citations

Ionic channels of excitable membranes

1985 • 1,185 citations

The Nature of the Frog Skin Potential

1958 • 1,163 citations

Single channel recording

1984 • 981 citations

Amiloride: a molecular probe of sodium transport in tissues and cells

1982 • 837 citations

Conduction and selectivity in potassium channels

1983 • 665 citations

The Kidney: Physiology and Pathophysiology.

1985 • 665 citations

Calcium-activated potassium channels and their role in secretion

1984 • 659 citations

Electrically silent cotransport of Na+, K+ and Cl− in ehrlich cells

1980 • 495 citations

The anomalous rectification and cation selectivity of the membrane of a starfish egg cell

1974 • 394 citations

Three types of calcium‐dependent channel in rat lacrimal glands.

1984 • 359 citations

Current—voltage curve of sodium channels and concentration dependence of sodium permeability in frog skin

1977 • 321 citations

Osmotic Behaviour of the Epithelial Cells of Frog Skin

1961 • 297 citations

Sodium-Specific Membrane Channels of Frog Skin Are Pores: Current Fluctuations Reveal High Turnover

1977 • 279 citations

An Apical-Membrane Chloride Channel in Human Tracheal Epithelium

1986 • 206 citations

Single-channel currents in isolated patches of plasma membrane from basal surface of pancreatic acini

1982 • 206 citations

Volume regulation by human lymphocytes. Role of calcium.

1982 • 204 citations

Incorporation of cytoplasmic vesicles into apical membrane of mammalian urinary bladder epithelium

1982 • 189 citations

The mechanism of Na+ transport by rabbit urinary bladder

1976 • 187 citations

Quantification of Ca2+-activated K+ channels under hormonal control in pig pancreas acinar cells

1983 • 184 citations

Formation of planar bilayers from artificial or native membrane vesicles

1980 • 182 citations

Aldosterone control of the density of sodium channels in the toad urinary bladder

1982 • 178 citations

Cholecystokinin activation of single-channel currents is mediated by internal messenger in pancreatic acinar cells

1982 • 177 citations

Single-channel recordings of apical membrane chloride conductance in A6 epithelial cells

1984 • 174 citations

Amiloride-sensitive trypsinization of apical sodium channels. Analysis of hormonal regulation of sodium transport in toad bladder.

1983 • 171 citations

The amiloride-sensitive sodium channel

1986 • 167 citations

Nystatin as a probe for investigating the electrical properties of a tight epithelium.

1977 • 164 citations

A large anion-selective channel has seven conductance levels

1986 • 161 citations

Concentration dependence of currents through single sodium-selective pores in frog skin

1979 • 155 citations

The role of sodium-channel density in the natriferic response of the toad urinary bladder to an antidiuretic hormone

1982 • 154 citations

Active and passive properties of rabbit descending colon: A microelectrode and nystatin study

1979 • 148 citations

Ionic channels in epithelial cell membranes

1985 • 148 citations

Single-channel recordings from amiloride-sensitive epithelial sodium channel

1985 • 142 citations

Volume regulation of frog skin epithelium

1982 • 141 citations

Cl?-channels in the apical cell membrane of the rectal gland ?induced? by cAMP

1985 • 129 citations

Methylation Increases Sodium Transport into A6 Apical Membrane Vesicles: Possible Mode of Aldosterone Action

1984 • 121 citations

Fluctuation Analysis of Sodium Channels in Epithelia

1984 • 121 citations

Tetrodotoxin, saxitoxin, and the molecular biology of the sodium channel.

1986 • 119 citations

Identification of a voltage-dependent anion channel in the apical membrane of a Cl?-secretory epithelium (MDCK)

1985 • 118 citations

Current-voltage analysis of apical sodium transport in toad urinary bladder: Effects of inhibitors of transport and metabolism

1980 • 117 citations

Sodium uptake by frog skin and its modification by inhibitors of transepithelial sodium transport

1973 • 115 citations

Ion selectivity of the apical membrane Na channel in the toad urinary bladder

1982 • 112 citations

Basolateral membrane potential of a tight epithelium: Ionic diffusion and electrogenic pumps

1978 • 105 citations

A patch‐clamp study of potassium channels and whole‐cell currents in acinar cells of the mouse lacrimal gland.

1984 • 103 citations

Ion conductance and ion selectivity of potassium channels in snail neurones

1980 • 102 citations

Apical membrane area of rabbit urinary bladder increases by fusion of intracellular vesicles: An electrophysiological study

1984 • 97 citations

Single channel recordings from basolateral and apical membranes of renal proximal tubules

1984 • 95 citations

Amiloride-sensitive epithelial Na+ channels reconstituted into planar lipid bilayer membranes

1984 • 94 citations

Mechanisms of transport of Na, Cl, and K in the human colon

1978 • 92 citations

Hormonal control of apical membrane Na transport in epithelia. Studies with fluctuation analysis.

1983 • 88 citations

Active potassium transport by rabbit descending colon epithelium

1982 • 87 citations

Ba2+-Induced conductance fluctuations of spontaneously fluctuating K+ channels in the apical membrane of frog skin (Rana temporaria)

1980 • 86 citations

Low-noise amplification of voltage and current fluctuations arising in epithelia

1978 • 76 citations

Effects of anions on cellular volume and transepithelial Na+ transport across toad urinary bladder

1985 • 65 citations

Wirkungscharakteristika eines neuen Aeylguanidins — Amiloride-HCL (MK 870) — an der isolierten Haut von Amphibien

1967 • 65 citations

Sodium-Coupled Sugar Transport: Effects on Intracellular Sodium Activities and Sodium-Pump Activity

1984 • 62 citations

Intracellular Na+ activity as a function of Na+ transport rate across a tight epithelium

1980 • 59 citations

Noise analysis of inward and outward Na+ currents across the apical border of ouabain-treated frog skin

1983 • 57 citations

Spontaneous fluctuations of potassium channels in the apical membrane of frog skin.

1980 • 57 citations

Photoaffinity labeling of the epithelial sodium channel.

1986 • 56 citations

CONTROL OF APICAL SODIUM PERMEABILITY IN THE TOAD URINARY BLADDER BY ALDOSTERONE

1981 • 56 citations

Single-Channel Fluctuations in Bimolecular Lipid Membranes Induced by Rat Olfactory Epithelial Homogenates

1983 • 55 citations

The beginning of fluctuation analysis of epithelial ion transport

1980 • 55 citations

Chemical stimulation of Na transport through amiloride-blockable channels of frog skin epithelium

1983 • 53 citations

Autoregulation of apical membrane Na+ permeability of tight epithelia. Noise analysis with amiloride and CGS 4270.

1985 • 53 citations

K+ transport in ‘tight’ epithelial monolayers of MDCK cells

1982 • 53 citations

Chloride channels in toad skin

1982 • 53 citations

Studies of sodium channels in rabbit urinary bladder by noise analysis

1984 • 52 citations

Na+ channels and amiloride-induced noise in the mammalian colon epithelium

1982 • 51 citations

Noise analysis reveals K+ channel conductance fluctuations in the apical membrane of rabbit colon

1982 • 51 citations

Fluctuation analysis of short-circuit current in a warm-blooded sodium-retaining epithelium: Site current, density, and interaction with triamterene

1982 • 51 citations

Saturation behavior of single, amiloride-sensitive Na+ channels in planar lipid bilayers

1984 • 49 citations

Metabolic regulation of apical sodium permeability in toad urinary bladder in the presence and absence of aldosterone

1983 • 49 citations

The application of patch clamp methods to ocular epithelia

1985 • 48 citations

Control of K+ conductance by cholecystokinin and Ca2+ in single pancreatic acinar cells studied by the patch-clamp technique

1984 • 48 citations

Ca2+-dependent, temperature-sensitive regulation of Na+ channels in tight epithelia. A study using membrane vesicles.

1985 • 47 citations

ION CHANNELS IN LIPOSOMES

1984 • 46 citations

New Insights into Cell and Membrane Transport Processes

1986 • 45 citations

Competitive blocking of epithelial sodium channels by organic cations: The relationship between macroscopic and microscopic inhibition constants

1983 • 44 citations

Patch Clamp Recordings from the Epithelium of the Lens Obtained using Glasses Selected for Low Noise and Improved Sealing Properties

1984 • 44 citations

Apical and basolateral membrane ionic channels in rabbit urinary bladder epithelium

1985 • 42 citations

Aldosterone-stimulated sodium uptake by apical membrane vesicles from A6 cells.

1984 • 42 citations

Saturable K+ pathway across the outer border of frog skin (Rana temporaria): Kinetics and inhibition by Cs+ and other cations

1979 • 41 citations

Apical membrane potassium and chloride permeabilities in surface cells of rabbit descending colon epithelium.

1985 • 40 citations

Single channel recordings obtained from basolateral membranes of isolated rabbit enterocytes

1985 • 40 citations

The electrical basis for enhanced potassium secretion in rat distal colon during dietary potassium loading

1985 • 37 citations

Current-voltage relationship of the basolateral membrane of a tight epithelium

1979 • 37 citations

The selectivity of the delayed potassium conductance of frog skeletal muscle fibers

1978 • 36 citations

Potassium channels in the apical membrane of the toad gallbladder

1978 • 35 citations

Na+ transport and flux ratio through apical Na+ channels in toad bladder

1982 • 34 citations

Fluctuation of No and K Currents in Excitable Membranes

1982 • 31 citations

Physiological role of apical potassium ion channels in frog skin.

1984 • 31 citations

KCl transport across an insect epithelium: II. Electrochemical potentials and electrophysiology

1984 • 31 citations

A fluctuation analysis study of the development of amiloride-sensitive Na+ transport in the skin of larval bullfrogs (Rana catesbeiana)

1982 • 31 citations

The interaction of “K+-like” cations with the apical K+ channel in frog skin

1983 • 31 citations

Feedback inhibition of sodium uptake in K+-depolarized toad urinary bladders

1984 • 31 citations

Leakage-channel conductance of single (Na+ + K+)-ATPase molecules incorporated into planar bilayers by fusion of liposomes

1984 • 27 citations

Attenuation of current and voltage noise signals recorded from epithelia

1980 • 27 citations

Basolateral K channels in an insect epithelium. Channel density, conductance, and block by barium.

1986 • 27 citations

Interpretation of 1/F fluctuations in ion conducting membranes

1985 • 26 citations

Quinidine blockage of K+ channels in the basolateral membrane of larval bullfrog skin

1985 • 25 citations

Epithelial transport of potassium

1977 • 25 citations

Control of Na+ and Water Absorption Across Vertebrate ‘Tight’ Epithelia By ADH and Aldosterone

1983 • 24 citations

Apical K+ channels in frog skin (Rana temporaria): Cation adsorption and voltage influence gating kinetics

1981 • 19 citations

Channels across Epithelial Cell Layers

1984 • 19 citations

Membranes, Channels, and Noise

1984 • 18 citations

Three functions of sodium channels in the toad node of Ranvier are altered by trimethyloxonium ions

1985 • 17 citations

Competitive blocking of apical sodium channels in epithelia

1983 • 17 citations

The effect of electrical gradients on current fluctuations and impedance recorded fromNecturus gallbladder

1981 • 17 citations

Surface potentials and sodium entry in frog skin epithelium.

1981 • 13 citations

Chapter 4 Mechanisms of Ion Transport by the Mammalian Colon Revealed by Frequency Domain Analysis Techniques

1984 • 12 citations

THE ROLE OF LIPID METABOLISM IN THE RESPONSE OF THE TOAD URINARY BLADDER TO ALDOSTERONE*

1981 • 10 citations

Channels in the Junctions between Cells

1984 • 8 citations

Zur Konformation von Makroglobulinen

1965 • 8 citations

Noise analysis of the K+ current through the apical membrane ofNecturus gallbladder

1981 • 5 citations

Analysis of additively contaminated Lorentzians by integration

1984 • 3 citations