Age-related methylation changes in DNA may reflect the proliferative potential of organs

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells

1982 • 1,002 citations

The 5-methylcytosine content of DNA from human tumors

1983 • 835 citations

DNA Methylation Decreases in Aging But Not in Immortal Cells

1983 • 635 citations

Quantitative changes in DNA, RNA, and protein during prenatal and postnatal growth in the rat

1965 • 617 citations

Genomic 5-methyldeoxycytidine decreases with age.

1987 • 504 citations

DNA methylation patterns Formation and function

1984 • 312 citations

Hypomethylation of DNA in pathological conditions of the human prostate.

1987 • 219 citations

The Isolation of High Molecular Weight Eukaryotic DNA

2003 • 218 citations

Tissue-specific differences in DNA methylation in various mammals

1983 • 204 citations

The content of 5-methylcytosine in animal DNA: The species and tissue specificity

1973 • 153 citations

Methylation of reiterated sequences in mammalian DNAs Effects of the tissue type, age, malignancy and hormonal induction

1981 • 140 citations

Quantitative determination of 5-methylcytosine in DNA by reverse-phase high-performance liquid chromatography

1983 • 95 citations

Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA

1989 • 74 citations

Cell renewal in the organs and tissues of the nongrowing adult mouse.

1970 • 66 citations

The 5‐methylcytosine content of DNA: Tissue specificity

1971 • 59 citations

Postnatal development of peroxisomal and mitochondrial enzymes in rat liver

1979 • 58 citations

Die DNS-synthese im rattenherzen als funktion des lebensalters. Autoradiographische untersuchungen mit3H-thymidin

1968 • 46 citations

Hypermethylation of human DNA sequences in embryonal carcinoma cells and somatic tissues but not in sperm

1987 • 41 citations

Methylation of the c-myc gene changes during aging process of mice

1986 • 36 citations

Heart anatomy and developmental biology

1988 • 29 citations

Nuclear chromatin changes during post-natal myocardial development

1978 • 8 citations

DNA methylation in differentiating mouse teratocarcinoma and erythroleukemia cells

1984 • 6 citations