Recovery from unilateral 6-hydroxydopamine lesion of substantia nigra promoted by the neurotachykinin substance P1–11

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

1970 • 1,980 citations

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

1990 • 1,975 citations

Amphetamine, Haloperidol, and Experience Interact to Affect Rate of Recovery After Motor Cortex Injury

1982 • 916 citations

Neurotoxicity of a Fragment of the Amyloid Precursor Associated with Alzheimer's Disease

1989 • 904 citations

Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterization

1980 • 498 citations

Regional distribution of substance P in the brain of the rat

1976 • 417 citations

Hyperactivity of Remaining Dopaminergic Neurones after Partial Destruction of the Nigro-striatal Dopaminergic System in the Rat

1973 • 363 citations

Evidence for the existence of substance P-containing fibres in striato-nigral and pallido-nigral pathways in rat brain

1977 • 334 citations

On the origin of substance P and glutamic acid decarboxylase (GAD) in the substantia nigra

1977 • 314 citations

A comparison of the anatomical distribution of substance P and substance P receptors in the rat central nervous system

1984 • 310 citations

Peptides and the blood-brain barrier: Lipophilicity as a predictor of permeability

1985 • 297 citations

Projections of substance P containing neurons from neostriatum to substantia nigra

1977 • 249 citations

Nigrostriatal lesions enhance striatal 3H-apomorphine and 3H-spiroperidol binding

1979 • 237 citations

Increase of enkephalin and decrease of substance P immunoreactivity in the dorsal and ventral striatum of the rat after midbrain 6-hydroxydopamine lesions

1987 • 182 citations

Dopamine receptor changes following destruction of the nigrostriatal pathway: Lack of a relationship to rotational behavior

1981 • 164 citations

Time Course of Adaptations in Dopamine Biosynthesis, Metabolism, and Release Following Nigrostriatal Lesions: Implications for Behavioral Recovery from Brain Injury

1987 • 160 citations

Effects of intranigral application of dopamine and substance P on the in vivo release of newly synthesized [3H]-dopamine in the ipsilateral caudate nucleus of the cat

1977 • 152 citations

Decrease of substance P-like immunoreactivity in the substantia nigra and pallidum of parkinsonian brains

1983 • 148 citations

Increased dopamine efflux from striatal slices during development and after nigrostriatal bundle damage

1987 • 143 citations

Tissue levels and in vivo release of tachykinins and GABA in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation

1989 • 139 citations

Differential modulation of striatal dopamine release by intranigral injection of γ-aminobutyric acid (GABA), dynorphin A and substance P

1988 • 133 citations

Post-Lesion Neural Plasticity

1988 • 125 citations

STIMULATORY EFFECTS OF SUBSTANCE P ON NEURITE EXTENSION AND CYCLIC AMP LEVELS IN CULTURED NEUROBLASTOMA CELLS

1978 • 115 citations

Effects of corticotrophin (ACTH) on recovery of sensorimotor function in the rat: Structure-activity study

1981 • 113 citations

Striato-nigral dynorphin and substance P pathways in the rat

1986 • 113 citations

Visualization of rat brain receptors for the neuropeptide, substance P

1984 • 106 citations

Brain Function: Neural Adaptations and Recovery From Injury

1984 • 103 citations

The relationship between reinforcement and memory: Parallels in the rewarding and mnemonic effects of the neuropeptide substance P

1989 • 103 citations

Haloperidol-induced reduction of nigral substance P-like immunoreactivity: a probe for the interactions between dopamine and substance P neuronal systems.

1981 • 102 citations

Substance P Counteracts Neurotoxin Damage on Norepinephrine Neurons in Rat Brain During Ontogeny

1982 • 97 citations

Substance P and neurokinin A regulate by different mechanisms dopamine release from dendrites and nerve terminals of the nigrostriatal dopaminergic neurons

1988 • 94 citations

Immunohistochemical evidence for a “neurotoxic” action of (D‐Pro², D‐Trp^7,9)‐substance P, an analogue with substance P antagonistic activity

1981 • 93 citations

EFFECTS OF SUBSTANCE P INJECTED INTO THE SUBSTANTIA NIGRA

1979 • 92 citations

Antinociceptive and neurotoxic actions of substance P analogues in the rat's spinal cord after intrathecal administration

1985 • 90 citations

Relationships between indices of behavioral asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injections

1991 • 89 citations

Immunocytochemical Studies of Substance P and Met-Enkephalin in the Basal Ganglia and Substantia Nigra in Huntingtonʼs, Parkinsonʼs and Alzheimerʼs Diseases

1985 • 84 citations

Amphetamine and apomorphine restore tactile placing after motor cortex injury in the cat

1983 • 83 citations

Increased dopamine metabolism in rat striatum after infusions of substance P into the substantia nigra

1978 • 82 citations

Supersensitivity after intraventricular 6-hydroxydopamine: Relation to dopamine depletion

1980 • 78 citations

Trophic effect of various neuropeptides on the cultured ventral spinal cord of rat embryo

1989 • 76 citations

Substance P infusion into substantia nigra of the rat: Behavioural analysis and ionvolvemetn of striatal dopamine

1979 • 73 citations

Innervation of substance P neurons by catecholaminergic terminals in the neostriatum

1986 • 70 citations

Substance P immunoreactivity in the post-mortem parkinsonian brain

1984 • 69 citations

Video image analysis of behavior by microcomputer: categorization of turning and locomotion after 6-OHDA injection into the substantia nigra

1987 • 69 citations

Effects of substance P on extracellular dopamine in neostriatum and nucleus accumbens

1992 • 68 citations

Functional recovery after destruction of dopamine systems in the nucleus accumbens of rats. II. Facilitation by the ACTH-(4–9) analog ORG 2766

1990 • 63 citations

An ACTH4–9 analog (ORG 2766) speeds recovery from septal hyperemotionality in the rat

1983 • 60 citations

Response of striatonigral substance P systems to a dopamine receptor agonist and antagonist

1981 • 58 citations

Accelerated regeneration of central catecholamine fibers in cat occipital cortex: effects of substance P

1984 • 56 citations

Reinforcing effects of peripherally administered substance P and its C-terminal sequence pGlu6-SP6-11 in the rat

1990 • 50 citations

Enhanced inhibitory avoidance learning produced by post-trial injections of substance P into the basal forebrain

1988 • 50 citations

Lateralized wall-facing versus turning as measures of behavioral asymmetries and recovery of function after injection of 6-hydroxydopamine into the substantia nigra

1988 • 48 citations

Substance P modifies the 6-hydroxydopamine induced alteration of postnatal development of central noradrenaline neurons

1982 • 48 citations

Substance P injected into the region of the nucleus basalis magnocellularis facilitates performance of an inhibitory avoidance task

1986 • 46 citations

Pharmacological analysis of central actions of synthetic substance P.

1973 • 45 citations

Facilitation of conditioned inhibitory avoidance by post-trial peripheral injection of substance P1

1986 • 42 citations

Nigrostriatal dopamine neurons are required to maintain basal levels of substance P in the rat substantia nigra

1989 • 41 citations

Short-term effects of ether, equithesin and droperidol/fentanyl on catecholamine and indolamine metabolism in the brain of the rat

1987 • 41 citations

Central action of substance P: Possible role in reward

1985 • 41 citations

Substance P enhancement of inhibitory avoidance learning: Mediation by the N-terminal sequence

1990 • 40 citations

Nigrostriatal dopamine neurons receive substance P-ergic inputs in the substantia nigra: application of the immunoelectron microscopic mirror technique to fluorescent double-staining for transmitter-specific projections

1987 • 40 citations

Substance P facilitation of memory: Effects in an appetitively motivated learning task

1986 • 39 citations

Dopamine and Serotonin Metabolism in Brain Sites Ipsi‐ and Contralateral to Direction of Conditioned Turning in Rats

1987 • 36 citations

Neuropeptide substance P improves water maze performance in aged rats

1990 • 35 citations

D-Amphetamine reduces striatal substance P concentrations by presynaptic release of dopamine

1980 • 30 citations

Effect of substance P on the 5,7-dihydroxytryptamine induced alteration of the postnatal development of central serotonin neurons.

1983 • 27 citations

Effect of substance P on the retention of a brightness discrimination task in rats

1982 • 22 citations

Some observations indicating a low brain uptake of [3H]Nle11-Substance P.

1983 • 22 citations

Progabide reverses the nigral substance P reduction induced by chronic impairment of dopaminergic transmission

1985 • 21 citations

Differential Effects of Tachykinins Injected Intranigrally on Striatal Dopamine Metabolism

1988 • 19 citations

Effect of Substance P on Vestibular Compensation

1988 • 18 citations

Baseline and apomorphine-induced extracellular levels of nigral substance P are increased in an animal model of Parkinson's disease

1990 • 14 citations

Activating effect of substance P on nerve tissue in culture

1987 • 9 citations