MRI relapses have significant pathologic and clinical implications in multiple sclerosis

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

2001 • 6,888 citations

Cortical demyelination and diffuse white matter injury in multiple sclerosis

2005 • 1,732 citations

A Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis

2003 • 1,228 citations

Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance

2002 • 635 citations

Axonal damage correlates with disability in patients with relapsing- remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study

1998 • 499 citations

Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis

1999 • 490 citations

Progressive cerebral atrophy in multiple sclerosis A serial MRI study

1996 • 482 citations

Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis

1999 • 467 citations

Accumulation of hypointense lesions ("black holes") on T ₁ spin-echo MRI correlates with disease progression in multiple sclerosis

1996 • 451 citations

Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis

1999 • 426 citations

SERIAL GADOLINIUM ENHANCED MAGNETIC RESONANCE IMAGING IN MULTIPLE SCLEROSIS

1988 • 397 citations

Magnetic resonance imaging results of the PRISMS trial: A randomized, double-blind, placebo-controlled study of interferon-?1a in relapsing-remitting multiple sclerosis

1999 • 384 citations

Evidence for adaptive functional changes in the cerebral cortex with axonal injury from multiple sclerosis

2000 • 313 citations

fMRI evidence of brain reorganization during attention and memory tasks in multiple sclerosis

2004 • 305 citations

Correlations between changes in disability and T ₂ ‐weighted brain MRI activity in multiple sclerosis

1995 • 297 citations

The motor cortex shows adaptive functional changes to brain injury from multiple sclerosis

2000 • 269 citations

Multiple sclerosis: histopathologic and MR and/or CT correlation in 37 cases at biopsy and three cases at autopsy.

1991 • 267 citations

Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy

1999 • 205 citations

Heterogeneity of blood‐brain barrier changes in multiple sclerosis

1990 • 201 citations

Brain atrophy in relapsing-remitting multiple sclerosis: relationship with ‘black holes’, disease duration and clinical disability

2000 • 122 citations

A prospective survey of the causes of non-traumatic spastic paraparesis and tetraparesis in 585 patients

1997 • 122 citations

Multiple Sclerosis: Lessons from Neuropathology

1998 • 107 citations

Magnetization Transfer Ratio Histogram Analysis of Normal-Appearing Gray Matter and Normal-Appearing White Matter in Multiple Sclerosis

2002 • 101 citations

Simple and complex movement‐associated functional MRI changes in patients at presentation with clinically isolated syndromes suggestive of multiple sclerosis

2003 • 98 citations

Disability in multiple sclerosis is related to normal appearing brain tissue MTR histogram abnormalities

2003 • 88 citations

The relationship between lesion and normal appearing brain tissue abnormalities in early relapsing remitting multiple sclerosis

2002 • 75 citations

Neuropathology of Multiple Sclerosis

2015 • 53 citations

Inflammation and atrophy in multiple sclerosis: MRI associations with disease course

2001 • 40 citations

Is Gadolinium Enhancement Predictive of the Development of Brain Atrophy in Multiple Sclerosis? A Review of the Literature

2002 • 26 citations

Neuroimaging in multiple sclerosis

2005 • 13 citations