Protein kinase C‐α and ‐ε are enriched in growth cones of differentiating SH‐SY5Y human neuroblastoma cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

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2007 • 11,720 citations

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.

1973 • 1,284 citations

Protein kinase C - a question of specificity

1994 • 958 citations

Protein kinase C

1991 • 914 citations

Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones.

1986 • 526 citations

A Protein Induced During Nerve Growth (GAP-43) is a Major Component of Growth-Cone Membranes

1986 • 505 citations

Protein kinase C ζ isoform is critical for mitogenic signal transduction

1993 • 383 citations

Association of type 3 protein kinase C with focal contacts in rat embryo fibroblasts.

1989 • 310 citations

Activation of the c-Raf protein kinase by protein kinase C phosphorylation.

1992 • 288 citations

Phenotypic changes of human neuroblastoma cells in culture induced by 12‐O‐tetradecanoyl‐phorbol‐13‐acetate

1981 • 255 citations

Protein kinase C phosphorylates pp60src at a novel site

1985 • 243 citations

Monoclonal antibodies show that kinase C phosphorylation of GAP-43 during axonogenesis is both spatially and temporally restricted in vivo.

1991 • 174 citations

Depletion of 43-kD growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones.

1993 • 173 citations

Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation.

1987 • 163 citations

Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation.

1991 • 141 citations

Tubulin is phosphorylated at tyrosine by pp60c-src in nerve growth cone membranes.

1990 • 137 citations

Activation of beta-isozyme of protein kinase C (PKC beta) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes. Studies with PKC beta-defective PET mutant.

1994 • 135 citations

Characterization, sequence, and expression of the cloned human neuropeptide Y gene.

1986 • 135 citations

Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells

1983 • 115 citations

Phosphorylation-site mutagenesis of the growth-associated protein GAP-43 modulates its effects on cell spreading and morphology.

1993 • 101 citations

A role for zeta protein kinase C in nerve growth factor-induced differentiation of PC12 cells.

1994 • 90 citations

Basic FGF and IGF-I Promote Differentiation of Human SH-SY5Y Neuroblastoma Cells in Culture

1994 • 73 citations

Differential Expression and Subcellular Localization of Protein Kinase C α, β, γ, δ, and ɛ Isoforms in SH‐SY5Y Neuroblastoma Cells: Modifications During Differentiation

1993 • 68 citations

Staurosporine-induced neurite outgrowth in PC12 cells is independent of protein kinase C inhibition.

1992 • 61 citations

Protein kinase inhibitor, staurosporine, induces a mature neuronal phenotype in SH‐SY5Y human neuroblastoma cells through an α‐, β‐, and ζ‐protein kinase C‐independent pathway

1993 • 58 citations

Staurosporine induces a neuronal phenotype in SH‐SY5Y human neuroblastoma cells that resembles that induced by the phorbol ester 12‐O‐tetradecanoyl phorbol‐13 acetate TPA)

1992 • 53 citations

Distinct Mechanisms of Differentiation of SH‐SY5Y Neuroblastoma Cells by Protein Kinase C Activators and Inhibitors

1992 • 50 citations

Fibroblast growth factor stimulates protein kinase C in quiescent 3T3 cells without Ca²⁺ mobilization or inositol phosphate accumulation

1990 • 48 citations

Protein kinase C activation and down‐regulation in relation to phorbol ester‐induced differentiation of SH‐SY5Y human neuroblastoma cells

1989 • 48 citations

Opposing influences of protein kinase activities on neurite outgrowth in human neuroblastoma cells: Initiation by kinase A and restriction by kinase C

1992 • 46 citations

Protein kinase C remains functionally active during TPA induced neuronal differentiation of SH-SY5Y human neuroblastoma cells

1992 • 45 citations

The Selective Protein Kinase C Inhibitor GF 109203X Inhibits Phorbol Ester-Induced Morphological and Functional Differentiation of SH-SY5Y Human Neuroblastoma Cells

1993 • 43 citations

Specific role for protein kinase C beta in cell differentiation.

1994 • 37 citations

Human GAP-43 Gene Expression: Multiple Start Sites for Initiation of Transcription in Differentiating Human Neuroblastoma Cells

1993 • 36 citations

Platelet-derived growth factor potentiates phorbol ester-induced neuronal differentiation of human neuroblastoma cells.

1992 • 35 citations

A role for protein kinase C subtypes α and ε in phorbol-ester-enhanced K+- and carbachol-evoked noradrenaline release from the human neuroblastoma SH-SY5Y

1994 • 31 citations

Staurosporine-induced morphological differentiation of human neuroblastoma cells

1991 • 28 citations

Effects of bryostatins 1 and 2 on morphological and functional differentiation of SH-SY5Y human neuroblastoma cells.

1990 • 22 citations

A complex consisting of pp60c-src/pp60c-srcN and a 38 kDa protein is highly enriched in growth cones from differentiated SH-SY5Y neuroblastoma cells

1992 • 18 citations

pp59^fyn and pp62^c‐yes are enriched in SH‐SY5Y neuroblastoma growth cones but do not associate to the 38 kDa protein which complexes with pp60^{c src} and pp60^c‐srcN

1993 • 8 citations

Production and characterization of antibodies against C-terminal peptide of protein F1: A novel phosphorylation at serine 209 of the peptide by protein kinase C

1994 • 3 citations