Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly

Clinical Applications of Research on Angiogenesis

1995 • 2,300 citations

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.

2000 • 1,536 citations

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

1990 • 1,308 citations

Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

2000 • 1,159 citations

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

1993 • 1,086 citations

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1999 • 990 citations

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Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.

1999 • 866 citations

The microtubule-affecting drug paclitaxel has antiangiogenic activity.

1996 • 643 citations

Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol.

1997 • 525 citations

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

1990 • 452 citations

Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti‐cancer therapeutic agents

1991 • 441 citations

The Ras superfamily of GTPases ¹

1996 • 269 citations

A Novel, Microcarrier-Based in Vitro Assay for Rapid and Reliable Quantification of Three-Dimensional Cell Migration and Angiogenesis

1995 • 244 citations

‘Accidental’ anti-angiogenic drugs

2000 • 181 citations

Inhibition of growth of colon 38 adenocarcinoma by vinblastine and colchicine: Evidence for a vascular mechanism

1991 • 175 citations

Paclitaxel (Taxol): An Inhibitor of Angiogenesis in a Highly Vascularized Transgenic Breast Cancer

1999 • 169 citations

Selective inhibition of endothelial cell proliferation by fumagillin is not due to differential expression of methionine aminopeptidases

2000 • 95 citations

Antiangiogenic chemotherapeutic agents.

2000 • 40 citations