Identification and Characterization of YME1L1, a Novel Paraplegin-Related Gene

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Computational Method to Predict Mitochondrially Imported Proteins and their Targeting Sequences

1996 • 1,654 citations

The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein

1997 • 1,010 citations

‘DNA Strider’: a ‘C’ program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers

1988 • 1,010 citations

A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules

1991 • 848 citations

Spastic Paraplegia and OXPHOS Impairment Caused by Mutations in Paraplegin, a Nuclear-Encoded Mitochondrial Metalloprotease

1998 • 804 citations

A Physical Map of 30,000 Human Genes

1998 • 723 citations

HSP100/Clp proteins: a common mechanism explains diverse functions

1996 • 653 citations

A radiation hybrid map of the human genome

1996 • 457 citations

X–linked spastic paraplegia (SPG1), MASA syndrome and X–linked hydrocephalus result from mutations in the L1 gene

1994 • 426 citations

X–linked spastic paraplegia and Pelizaeus–Merzbacher disease are allelic disorders at the proteolipid protein locus

1994 • 348 citations

A 200‐amino acid ATPase module in search of a basic function

1995 • 339 citations

The YTA10–12 Complex, an AAA Protease with Chaperone-like Activity in the Inner Membrane of Mitochondria

1996 • 312 citations

Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease

1999 • 219 citations

Rearranged mitochondrial genes in the yeast nuclear genome

1983 • 196 citations

Idiopathic torsion dystonia: assignment of a gene to chromosome 18p in a German family with adult onset, autosomal dominant inheritance and purely focal distribution

1996 • 193 citations

Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching

1996 • 188 citations

Structural Neurology: Are Seeds at the Root of Neuronal Degeneration?

1997 • 172 citations

Promotion of Mitochondrial Membrane Complex Assembly by a Proteolytically Inactive Yeast Lon

1996 • 170 citations

Autosomal dominant familial spastic paraplegia is genetically heterogeneous and one locus maps to chromosome 14q

1993 • 165 citations

Mitochondrial DNA sequences in the nuclear genome of a locust

1983 • 160 citations

Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus.

1993 • 158 citations

Escape of mitochondrial DNA to the nucleus in ymel yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments

1998 • 150 citations

Autosomal dominant familial spastic paraplegia: tight linkage to chromosome 15q.

1995 • 144 citations

Linkage of a new locus for autosomal dominant familial spastic paraplegia to chromosome 2p

1994 • 142 citations

Biochemical and functional analysis of the YME1 gene product, an ATP and zinc-dependent mitochondrial protease from S. cerevisiae.

1996 • 138 citations

A New Locus for Autosomal Recessive Hereditary Spastic Paraplegia Maps to Chromosome 16q24.3

1998 • 136 citations

Linkage of ‘pure’ autosomal recessive familial spastic paraplegia to chromosome 8 markers and evidence of genetic locus heterogeneity

1994 • 129 citations

Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB)

1993 • 118 citations

Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex

1994 • 117 citations

The role of protein degradation in mitochondrial function and biogenesis

1996 • 105 citations

Pure hereditary spastic paraplegia.

1997 • 81 citations

Regulated protein degradation in mitochondria

1996 • 79 citations

Advances in hereditary spastic paraplegia

1997 • 69 citations

Genetic aspects of autosomal dominant late onset cerebellar ataxia.

1981 • 43 citations

X‐linked Kallmann syndrome

1993 • 38 citations

Chromosomal Locations of Three Human Nuclear Genes (RPSM12, TUFM, and AFG3L1) Specifying Putative Components of the Mitochondrial Gene Expression Apparatus

1998 • 24 citations