Expression in Escherichia coli of two mutated genes encoding the cholera toxin B subunit

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development

1983 • 645 citations

Actions of cholera toxin and the prevention and treatment of cholera

1981 • 532 citations

Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin.

1984 • 445 citations

Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens.

1986 • 428 citations

Polynucleotide Sequence Relationships among Members of Enterobacteriaceae

1969 • 260 citations

Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues

1989 • 252 citations

The product of the retroviral transforming gene v-myb is a truncated version of the protein encoded by the cellular oncogene c-myb

1983 • 197 citations

Cholera toxin B subunit as a carrier protein to stimulate a mucosal immune response.

1984 • 196 citations

Protection against influenza virus infection by vaccine inoculated intranasally with cholera toxin B subunit

1988 • 192 citations

Combined oral/nasal immunization protects mice from Sendai virus infection.

1987 • 177 citations

Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development.

1989 • 161 citations

Microtiter ganglioside enzyme-linked immunosorbent assay for vibrio and Escherichia coli heat-labile enterotoxins and antitoxin

1980 • 156 citations

Dissociation and Recombination of the Subunits of the Cholera Enterotoxin (Choleragen)

1974 • 150 citations

Coordinated assembly of multisubunit proteins: oligomerization of bacterial enterotoxins in vivo and in vitro.

1988 • 141 citations

Oral administration of cholera toxin-Sendai virus conjugate potentiates gut and respiratory immunity against Sendai virus.

1988 • 133 citations

Nucleotide sequence analysis of the A2 and B subunits of Vibrio cholerae enterotoxin.

1983 • 118 citations

Nucleotide sequence homology between the heat-labile enterotoxin gene of Escherichia coli and Vibrio cholerae deoxyribonucleic acid

1980 • 109 citations

Four major antigenic sites of the coronavirus transmissible gastroenteritis virus are located on the amino-terminal half of spike glycoprotein S

1990 • 105 citations

Synthesis, purification and initial structural characterization of octarellin, a de novo polypeptide modelled on the α/β-barrel Proteins

1990 • 85 citations

Genetic fusion of a non‐toxic heat‐stable enterotoxin‐related decapeptide antigen to cholera toxin B‐subunit

1988 • 78 citations

Alterations at the carboxyl terminus change assembly and secretion properties of the B subunit of Escherichia coli heat-labile enterotoxin

1987 • 63 citations

The expression of biologically active cholera toxin inEscherichia coli

1982 • 47 citations

Construction of a plasmid for expression of foreign epitopes as fusion proteins with subunit B of Escherichia coli heat-labile enterotoxin

1989 • 42 citations