Symptomatic Lactic Acidosis in Hospitalized Antiretroviral‐Treated Patients with Human Immunodeficiency Virus Infection: A Report of 12 Cases

DISEASES OF THE MITOCHONDRIAL DNA

1992 • 1,294 citations

Adverse effects of reverse transcriptase inhibitors

1998 • 853 citations

Mitochondrial toxicity of antiviral drugs

1995 • 760 citations

A syndrome of lipoatrophy, lactic acidaemia and liver dysfunction associated with HIV nucleoside analogue therapy: contribution to protease inhibitor-related lipodystrophy syndrome

2000 • 652 citations

Hepatic Failure and Lactic Acidosis Due to Fialuridine (FIAU), an Investigational Nucleoside Analogue for Chronic Hepatitis B

1995 • 605 citations

Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection

2000 • 527 citations

Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis

1994 • 344 citations

Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.

1991 • 286 citations

Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion

1999 • 256 citations

Hyperlactatemia and Hepatic Abnormalities in 10 Human Immunodeficiency Virus-Infected Patients Receiving Nucleoside Analogue Combination Regimens

2000 • 210 citations

Lactic Acidosis and Hepatic Steatosis Associated with Use of Stavudine: Report of Four Cases

2000 • 210 citations

Fulminant hepatitis with severe lactate acidosis in HIV‐infected patients on didanosine therapy

1994 • 141 citations

Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides

1994 • 139 citations

Assessing risk of the use of livers with macro and microsteatosis in a liver transplant program

1998 • 139 citations

Lactic Acidosis Complicating the Acquired Immunodeficiency Syndrome

1993 • 138 citations

Zidovudine-induced fatal lactic acidosis and hepatic failure in patients with acquired immunodeficiency syndrome

1997 • 137 citations

Lactic Acidosis Associated with Stavudine Administration: A Report of Five Cases

2000 • 131 citations

Cellular and molecular events leading to mitochondrial toxicity of 1-(2-deoxy-2-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil in human liver cells.

1995 • 123 citations

Differential Effects of Antiretroviral Nucleoside Analogs on Mitochondrial Function in HepG2 Cells

2000 • 122 citations

Massive Hepatic Steatosis and Lactic Acidosis in a Patient with AIDS Who Was Receiving Zidovudine

1995 • 115 citations

Depletion of mitochondrial DNA, destruction of mitochondria, and accumulation of lipid droplets result from fialuridine treatment in woodchucks (Marmota monax).

1997 • 58 citations

Effect of anti-HIV 2′-β-fluoro-2′,3′-dideoxynucleoside analogs on the cellular content of mitochondrial DNA and on lactate production

1994 • 39 citations