Efficient Utrophin Expression Following Adenovirus Gene Transfer in Dystrophic Muscle

Immune responses to transgene–encoded proteins limit the stability of gene expression after injection of replication–defective adenovirus vectors

1996 • 640 citations

Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene

1996 • 475 citations

Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.

1991 • 424 citations

Duchenne muscular dystrophy

1993 • 260 citations

Localization of the DMDL gene-encoded dystrophin-related protein using a panel of nineteen monoclonal antibodies: presence at neuromuscular junctions, in the sarcolemma of dystrophic skeletal muscle, in vascular and other smooth muscles, and in proliferating brain cell lines.

1991 • 258 citations

Expression of truncated utrophin leads to major functional improvements in dystrophin-deficient muscles of mice

1997 • 241 citations

A differential efficiency of adenovirus-mediated in vivo gene transfer into skeletal muscle cells of different maturity

1994 • 209 citations

Long–term correction of mouse dystrophic degeneration by adenovirus–mediated transfer of a minidystrophin gene

1993 • 201 citations

Emergence of Early Region 1-Containing Replication-Competent Adenovirus in Stocks of Replication-Defective Adenovirus Recombinants (ΔE1 + ΔE3) During Multiple Passages in 293 Cells

1994 • 193 citations

Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression

1997 • 186 citations

Immune Responses to Reporter Proteins and High Viral Dose Limit Duration of Expression with Adenoviral Vectors: Comparison of E2a Wild Type and E2a Deleted Vectors

1997 • 173 citations

Utrophin: A Structural and Functional Comparison to Dystrophin

1996 • 168 citations

Gene Transfer and Expression Protocols

1991 • 165 citations

Dystrophin Expression in Muscles of mdx Mice After Adenovirus-MediatedIn VivoGene Transfer

1996 • 149 citations

Dystrophin and utrophin: the missing links!

1995 • 142 citations

Localization and Quantitation of the Chromosome 6-Encoded Dystrophin-Related Protein in Normal and Pathological Human Muscle

1993 • 139 citations

Functional protection of dystrophic mouse (mdx) muscles after adenovirus-mediated transfer of a dystrophin minigene.

1996 • 126 citations

Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice.

1996 • 106 citations

Dystrophin distribution in heterozygote mdx mice

1989 • 54 citations

Dystrophin‐Associated Proteins and the Muscular Dystrophies: A Glossary

1996 • 41 citations

Generation, validation, and large scale production of adenoviral recombinants with large size inserts such as a 6.3 kb human dystrophin cDNA

1997 • 27 citations

Utrophin muscles in on the action

1997 • 22 citations