Angiotensin II–Induced Growth Responses in Isolated Adult Rat Hearts

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

1993 • 1,420 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response

1991 • 798 citations

Association between a Deletion Polymorphism of the Angiotensin-Converting-Enzyme Gene and Left Ventricular Hypertrophy

1994 • 757 citations

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.

1990 • 647 citations

Cardiac hypertrophy. Mechanical, neural, and endocrine dependence.

1991 • 625 citations

Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy.

1992 • 611 citations

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.

1990 • 607 citations

Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters

1988 • 597 citations

Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation.

1991 • 437 citations

Angiotensin II Induces c-fos mRNA in Aortic Smooth Muscle

1989 • 401 citations

Signal transduction pathways of angiotensin II--induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers.

1993 • 389 citations

Ramiprilat enhances endothelial autacoid formation by inhibiting breakdown of endothelium-derived bradykinin.

1991 • 361 citations

Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells

1990 • 358 citations

Regulation of Protein Synthesis in Heart Muscle

1971 • 350 citations

The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation

1989 • 286 citations

Rat angiotensin II (type 1A) receptor mRNA regulation and subtype expression in myocardial growth and hypertrophy.

1993 • 286 citations

Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly.

1990 • 245 citations

Relation of left ventricular hemodynamic load and contractile performance to left ventricular mass in hypertension.

1990 • 244 citations

Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis.

1994 • 240 citations

Characterization of angiotensin II receptor subtypes in rat heart.

1992 • 236 citations

BP as a Determinant of Cardiac Left Ventricular Muscle Mass

1983 • 215 citations

Regression of left ventricular hypertrophy from systemic hypertension by enalapril

1984 • 211 citations

Angiotensin II induces c-fos expression in smooth muscle via transcriptional control.

1989 • 206 citations

Distribution and function of cardiac angiotensin AT1- and AT2-receptor subtypes in hypertrophied rat hearts

1994 • 201 citations

Angiotensin II increases spontaneous contractile frequency and stimulates calcium current in cultured neonatal rat heart myocytes: insights into the underlying biochemical mechanisms.

1988 • 199 citations

Nature of the Inotropic Action of Angiotensin on Ventricular Myocardium

1965 • 159 citations

Age-related differences in the expression of proto-oncogene and contractile protein genes in response to pressure overload in the rat myocardium.

1992 • 154 citations

Load responsiveness of protein synthesis in adult mammalian myocardium: role of cardiac deformation linked to sodium influx.

1989 • 153 citations

Tumor-promoting phorbol esters inhibit cardiac functions and induce redistribution of protein kinase C in perfused beating rat heart.

1987 • 139 citations

Identification and characterization of guinea pig angiotensin II ventricular and atrial receptors: coupling to inositol phosphate production.

1988 • 129 citations

Aortic perfusion pressure as a determinant of cardiac protein synthesis

1984 • 110 citations

Localization and regulation of c-fos and c-jun protooncogene induction by systolic wall stress in normal and hypertrophied rat hearts.

1991 • 106 citations

Effects of long-term angiotensin converting enzyme inhibition on myocardial hypertrophy in experimental aortic stenosis in the rat

1988 • 106 citations

Repression of c-fos promoter by MyoD on muscle cell differentiation

1993 • 98 citations

ANG II receptors, c-myc, and c-jun in myocytes after myocardial infarction and ventricular failure

1993 • 94 citations

Phenylephrine, vasopressin and angiotensin II as determinants of proto-oncogene and heat-shock protein gene expression in adult rat heart and aorta

1989 • 81 citations

Angiotensin II and left ventricular growth in newborn pig heart

1991 • 79 citations

Angiotensin II receptor-mediated stimulation of cytosolic-free calcium and inositol phosphates in chick myocytes.

1989 • 79 citations

Effects of Angiotensin II on DNA, RNA and Protein Synthesis

1972 • 79 citations

Exacerbation of left ventricular ischemic diastolic dysfunction by pressure-overload hypertrophy. Modification by specific inhibition of cardiac angiotensin converting enzyme.

1992 • 74 citations

Action of atrial natriuretic peptide and angiotensin II on the myocardium: Studies in isolated rat ventricular cardiomyocytes

1989 • 68 citations

Proto-oncogene expression in proliferating and differentiating cardiac and skeletal muscle

1987 • 62 citations

Effects of diabetes on protein turnover in cardiac muscle

1980 • 61 citations

Dissociated expression of c-myc and a fos-related competence gene during cardiac myogenesis.

1986 • 51 citations

Coronary flow as a determinant of c-myc and c-fos proto-oncogene expression in an isolated adult rat heart

1988 • 50 citations

Angiotensin II increases cardiac protein synthesis in adult rat heart

1993 • 42 citations

Different pathways of inositol phosphate metabolism in intact neonatal rat hearts and isolated cardiomyocytes

1992 • 35 citations

Angiotensin II-binding protein in adult and neonatal rat heart

1991 • 23 citations

Exacerbation of ischemic dysfunction by angiotensin II in red cell-perfused rabbit hearts. Effects on coronary flow, contractility, and high-energy phosphate metabolism.

1992 • 18 citations

Control of growth in the neonatal pig heart

1991 • 15 citations

Control of growth in the neonatal pig heart

1991 • 5 citations