Tumor-promoting phorbol esters inhibit cardiac functions and induce redistribution of protein kinase C in perfused beating rat heart.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

1980 • 1,317 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Calcium channel modulation by neurotransmitters, enzymes and drugs

1983 • 1,267 citations

Protein kinase C activation by diacylglycerol second messengers

1986 • 498 citations

Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C

1985 • 476 citations

Interleukin-2 stimulates association of protein kinase C with plasma membrane

1985 • 384 citations

Kinase C activator 1,2-oleoylacetylglycerol attenuates voltage-dependent calcium current in sensory neurons.

1986 • 313 citations

Altered cytosol/membrane enzyme redistribution on interleukin-3 activation of protein kinase C

1985 • 255 citations

Phosphorylation of phospholamban by calcium-activated, phospholipid-dependent protein kinase. Stimulation of cardiac sarcoplasmic reticulum calcium uptake.

1984 • 255 citations

[116] Sodium and potassium-stimulated ATPase

1967 • 246 citations

Agonists differentiate muscarinic receptors that inhibit cyclic AMP formation from those that stimulate phosphoinositide metabolism.

1984 • 219 citations

Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase.

1985 • 193 citations

Tumor promoter phorbol myristate acetate inhibits Ca2+ influx through voltage-gated Ca2+ channels in two secretory cell lines, PC12 and RINm5F.

1986 • 178 citations

Plasma membrane calcium flux, protein kinase C activation and smooth muscle contraction.

1985 • 163 citations

Phosphorylation of cardiac troponin inhibitory subunit (troponin I) and tropomyosin-binding subunit (troponin T) by cardiac phospholipid-sensitive Ca2+-dependent protein kinase

1983 • 139 citations

Evidence that treatment of platelets with phorbol ester causes proteolytic activation of Ca²⁺‐activated, phospholipid‐dependent protein kinase

1985 • 121 citations

Phospholipid-sensitive Ca2+-dependent protein kinase: a major protein phosphorylation system

1984 • 120 citations

Immunological quantitation of phospholipid/Ca2+-dependent protein kinase and its fragments. Tissue levels, subcellular distribution, and ontogenetic changes in brain and heart.

1986 • 114 citations

Phosphorylation of cardiac sarcolemma proteins by the calcium-activated phospholipid-dependent protein kinase.

1984 • 111 citations

Phorbol ester induces intracellular translocation of phospholipid/Ca²⁺ ‐dependent protein kinase and stimulates amylase secretion in isolated pancreatic acini

1984 • 102 citations

Identification of an endogenous protein kinase C activity and its intrinsic 15-kilodalton substrate in purified canine cardiac sarcolemmal vesicles.

1985 • 95 citations

Phosphorylation of cardiac sarcoplasmic reticulum by a calcium-activated, phospholipid-dependent protein kinase

1980 • 82 citations

Substrate proteins for calmodulin-sensitive and phospholipid-sensitive Ca2+-dependent protein kinases in heart, and inhibition of their phosphorylation by palmitoylcarnitine.

1981 • 82 citations

Effects of phosphorylated and unphosphorylated C-protein on cardiac actomyosin ATPase

1985 • 74 citations

Subcellular distribution of phospholipid-sensitive calcium-dependent protein kinase in guinea pig heart, spleen and cerebral cortex, and inhibition of the enzyme by Triton X-100

1982 • 50 citations

Phosphorylation of bovine cardiac C-protein by protein kinase C

1985 • 43 citations

Characterization of the membrane-bound protein kinase C and its substrate proteins in canine cardiac sarcolemma

1986 • 34 citations

Cardiac function and phosphorylation of contractile proteins

1983 • 19 citations

Prostaglandin E₂ and cyclic AMP in the coronary vasodilatation due to cardiac hyperactivity

1976 • 15 citations

Phosphorylation of the myofibrillar proteins and the regulation of contractile activity in muscle

1983 • 10 citations

On the phorbol ester (TPA) action in rabbit SA node cells and canine Purkinje fibers

1986 • 1 citations