Doxorubicin induced alterations in lipid metabolism of cultured myocardial cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Phosphorus Assay in Column Chromatography

1959 • 12,895 citations

Removal of Fatty Acids from Serum Albumin by Charcoal Treatment

1967 • 2,098 citations

The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function

1984 • 1,616 citations

Relationship Between Carbohydrate and Lipid Metabolism and the Energy Balance of Heart Muscle

1974 • 1,252 citations

Regulation of membrane enzymes by lipids

1978 • 906 citations

The Anthracycline Antineoplastic Drugs

1981 • 794 citations

Enzymes of Glycerolipid Synthesis in Eukaryotes

1980 • 626 citations

The Anticancer Agent Adriamycin Can Be Actively Cytotoxic Without Entering Cells

1982 • 578 citations

Phosphoglyceride Metabolism

1974 • 416 citations

Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells.

1976 • 413 citations

Dimethoxypropane Induced Transesterification of Fats and Oils in Preparation of Methyl Esters for Gas Chromatographic Analysis.

1964 • 214 citations

Activation of pharmacologic agents to radical intermediates

1982 • 190 citations

In vitro Studies of Single Isolated Beating Heart Cells

1960 • 180 citations

Anthracycline glycoside-membrane interactions

1984 • 172 citations

Stimulation by adriamycin of rat heart and liver microsomal NADPH-dependent lipid peroxidation

1981 • 166 citations

Lipid composition and protein profiles of outer and inner membranes from pig heart mitochondria. Comparison with microsomes

1976 • 162 citations

Evidence of a complex between adriamycin derivatives and cardiolipin: Possible role in cardiotoxicity

1980 • 156 citations

Effects of anticancer agents on the respiration of isolated mitochondria and tumor cells

1974 • 154 citations

Inhibition of coenzyme Q10-enzymes, succinoxidase and NADH-oxidase, by adriamycin and other quinones having antitumor activity

1974 • 153 citations

Adriamycin inactivates cytochrome c oxidase by exclusion of the enzyme from its cardiolipin essential environment

1982 • 143 citations

Dynamic modulation of mitochondrial inner-membrane lipids in rat heart by dietary fat

1981 • 141 citations

Adriamycin: A proposal on the specificity of drug action

1978 • 130 citations

Biosynthesis of cardiolipin in liver mitochondria

1971 • 129 citations

Affinity of adriamycin to phospholipids a possible explanation for cardiac mitochondrial lesions

1976 • 128 citations

Brief Communication : Adriamycin-Induced Cardiac Damage in the Mouse: A Small-Animal Model of Cardiotoxicity

1975 • 110 citations

Adriamycin-induced changes in the surface membrane of sarcoma 180 ascites cells

1981 • 102 citations

Destruction of Phosphilipids and Respiratory‐Chain Activity in Pig=Heart Submitochondrial Particles Induced by an Adriamycin‐Iron Complex

1983 • 83 citations

Myocardial Injury Induced by a Single Dose of Adriamycin: An Electron Microscopic Study

1976 • 81 citations

The interaction of adriamycin with small unilamellar vesicle liposomes. A fluorescence study

1979 • 77 citations

Mitochondrial membrane modifications induced by adriamycin-mediated electron transport

1983 • 72 citations

Metabolism of the Phosphatidylglycerol Molecular Species in Escherichia coli

1975 • 72 citations

Differential modulation of rat heart mitochondrial membrane-associated enzymes by dietary lipid

1983 • 66 citations

Adriamycin inhibits the formation of non-bilayer lipid structures in cardiolipin-containing model membranes

1982 • 62 citations

The mitochondrial phosphate carrier reconstituted in liposomes is inhibited by doxorubicin

1983 • 59 citations

Decompostion of unsaturated phospholipid by iron-ADP-adriamycin co-ordination complex

1981 • 58 citations

A protective effect of coenzyme Q10 on the adriamycin-induced cardiotoxicity in the isolated perfused rat heart

1981 • 53 citations

Turnover of fatty acids in rat liver cardiolipin: Comparison with other mitochondrial phospholipids

1976 • 46 citations

Identification of cardiac myocytes in vivo and in vitro by the presence of glycogen and myofibrils

1973 • 46 citations

Compartmentalization of adriamycin and daunomycin in cultured chick cardiac myocytes. Effects on synthesis of contractile and cytoplasmic proteins.

1983 • 31 citations

Modification by adenosine of the effect of adriamycin on myocardial cells in culture.

1979 • 27 citations

Nuclear and mitochondrial effects of adriamycin in singly isolated pulsating myocardial cells

1979 • 18 citations

Ultrastructural Changes Produced in Cultured, Adriamycin-Treated Myocardial Cells^,

1976 • 15 citations

A stereological analysis of the effect of adriamycin on the ultrastructure of rat myocardial cells in culture

1980 • 10 citations

Anthracycline cardiomyopathy

1982 • 10 citations