Progenitor Marker CD133 mRNA Is Elevated in Peripheral Blood of Cancer Patients with Bone Metastases

Rapid and simple method for purification of nucleic acids

1990 • 5,273 citations

Identification of a cancer stem cell in human brain tumors.

2003 • 4,784 citations

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

2005 • 3,066 citations

Prospective Identification of Tumorigenic Prostate Cancer Stem Cells

2005 • 2,784 citations

Number and Migratory Activity of Circulating Endothelial Progenitor Cells Inversely Correlate With Risk Factors for Coronary Artery Disease

2001 • 2,344 citations

Kinetic PCR Analysis: Real-time Monitoring of DNA Amplification Reactions

1993 • 2,177 citations

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2001 • 1,874 citations

AC133, a Novel Marker for Human Hematopoietic Stem and Progenitor Cells

1997 • 1,755 citations

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

2002 • 1,066 citations

Circulating Activated Endothelial Cells in Sickle Cell Anemia

1997 • 653 citations

Vascular Endothelial Growth Factor ₁₆₅ Gene Transfer Augments Circulating Endothelial Progenitor Cells in Human Subjects

2000 • 570 citations

Contribution of bone marrow–derived endothelial cells to human tumor vasculature

2005 • 490 citations

Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells.

2003 • 458 citations

Resting and activated endothelial cells are increased in the peripheral blood of cancer patients

2001 • 426 citations

Differentiation and expansion of endothelial cells from human bone marrow CD133⁺ cells

2001 • 394 citations

Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis

2005 • 331 citations

Molecular beacon probes combined with amplification by NASBA enable homogeneous, real-time detection of RNA

1998 • 305 citations

Direct Evidence of Endothelial Injury in Acute Myocardial Infarction and Unstable Angina by Demonstration of Circulating Endothelial Cells

1999 • 304 citations

Circulating endothelial cells as markers for ANCA-associated small-vessel vasculitis

2003 • 292 citations

Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity

2005 • 256 citations

Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients

2003 • 247 citations

Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors

2003 • 245 citations

Chemokines direct endothelial progenitors into tumor neovessels

2005 • 238 citations

Endothelial progenitor cells in infantile hemangioma

2003 • 203 citations

Circulating endothelial progenitor cells in multiple myeloma: implications and significance

2004 • 200 citations

Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice.

2001 • 199 citations

G-CSF stimulates angiogenesis and promotes tumor growth: potential contribution of bone marrow-derived endothelial progenitor cells

2002 • 198 citations

AC133, a Novel Marker for Human Hematopoietic Stem and Progenitor Cells

1997 • 185 citations

Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesisImplications for cellular surrogate marker analysis of antiangiogenesis

2005 • 173 citations

Demonstration of Rickettsia conorii-induced endothelial injury in vivo by measuring circulating endothelial cells, thrombomodulin, and von Willebrand factor in patients with Mediterranean spotted fever [see comments]

1993 • 165 citations

Kinetics and viability of circulating endothelial cells as surrogate angiogenesis marker in an animal model of human lymphoma.

2001 • 163 citations

Differential Effects of Vascular Endothelial Growth Factor Receptor-2 Inhibitor ZD6474 on Circulating Endothelial Progenitors and Mature Circulating Endothelial Cells: Implications for Use as a Surrogate Marker of Antiangiogenic Activity

2005 • 160 citations

Characterization of Expression and Modulation of Cell Adhesion Molecules on an Immortalized Human Dermal Microvascular Endothelial Cell Line (HMEC-1)

1994 • 137 citations

Transplanted human bone marrow contributes to vascular endothelium

2004 • 134 citations

Differential CD146 Expression on Circulating Versus Tissue Endothelial Cells in Rectal Cancer Patients: Implications for Circulating Endothelial and Progenitor Cells As Biomarkers for Antiangiogenic Therapy

2006 • 131 citations

Continuous infusion of endostatin inhibits differentiation, mobilization, and clonogenic potential of endothelial cell progenitors.

2003 • 124 citations

Phase I Clinical Evaluation of Weekly Administration of the Novel Vascular-Targeting Agent, ZD6126, in Patients With Solid Tumors

2006 • 117 citations

Thalidomide in multiple myeloma, myelodysplastic syndromes and histiocytosis. Analysis of clinical results and of surrogate angiogenesis markers

2001 • 99 citations

Diagnosis of Mediterranean Spotted Fever by Indirect Immunofluorescence of Rickettsia conorii in Circulating Endothelial Cells Isolated with Monoclonal Antibody-Coated Immunomagnetic Beads

1992 • 88 citations

Nasba Technology: Isothermal RNA Amplification in Qualitative and Quantitative Diagnostics

1997 • 84 citations

Assessing Tumor Angiogenesis

2004 • 84 citations

Phase 1 Study of ABT-751, a Novel Microtubule Inhibitor, in Patients with Refractory Hematologic Malignancies

2005 • 78 citations

Large-scale isolation of CD133+ progenitor cells from G-CSF mobilized peripheral blood stem cells

2003 • 67 citations

Detection of HIV-1 RNA in plasma and serum samples using the NASBA amplification system compared to RNA-PCR

1995 • 61 citations

Circulating numbers of endothelial progenitor cells in patients with gastric and breast cancer

2003 • 53 citations

Direct Evidence of Endothelial Injury in Acute Myocardial Infarction and Unstable Angina by Demonstration of Circulating Endothelial Cells

1999 • 52 citations

Blood Markers for Vasculogenesis Increase with Tumor Progression in Patients with Breast Carcinoma

2003 • 49 citations

Endothelial precursors and mature endothelial cells are increased in the peripheral blood of myelodysplastic syndromes

2005 • 49 citations

Real-time PCR of CD146 mRNA in peripheral blood enables the relative quantification of circulating endothelial cells and is an indicator of angiogenesis

2005 • 49 citations

Levels of circulating endothelial cells (CECs) and monocytes as pharmacodynamic markers of SU11248 activity in patients (pts) with metastatic imatinib-resistant GIST

2005 • 16 citations

Hematopoietic Stem and Progenitor Cells

2005 • 13 citations