DNA Demethylase Is a Processive Enzyme

DNA Methylation and Gene Function

1980 • 2,069 citations

High sensitivity mapping of methylated cytosines

1994 • 1,863 citations

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

1987 • 1,088 citations

Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line.

1992 • 729 citations

A mammalian protein with specific demethylase activity for mCpG DNA

1999 • 624 citations

Reduced genomic 5-methylcytosine content in human colonic neoplasia.

1988 • 491 citations

Loss of Fibrinogen Rescues Mice from the Pleiotropic Effects of Plasminogen Deficiency

1996 • 428 citations

Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis.

1986 • 224 citations

DNA Demethylation In Vitro: Involvement of RNA

1996 • 188 citations

Variations in DNA methylation during mouse cell differentiation in vivo and in vitro.

1984 • 187 citations

Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation.

1986 • 175 citations

Developmental changes in methylation of spermatogenesis–specific genes include reprogramming in the epididymis

1994 • 161 citations

Mechanistic aspects of genome-wide demethylation in the preimplantation mouse embryo.

1993 • 138 citations

Dynamics of DNA methylation during development

1993 • 125 citations

Cellular and viral DNA hypomethylation associated with induction of Epstein-Barr virus lytic cycle.

1985 • 111 citations

Sequential changes in DNA methylation patterns of the rat phosphoenolpyruvate carboxykinase gene during development.

1985 • 107 citations

DNA methylation properties: consequences for pharmacology

1994 • 105 citations

Procaryotic and eucaryotic traits of DNA methylation in spiroplasmas (mycoplasmas)

1985 • 102 citations

Enzymic removal of 5-methylcytosine from DNA by a human DNA-glycosylase

1993 • 69 citations

Ras Induces a General DNA Demethylation Activity in Mouse Embryonal P19 Cells

1995 • 58 citations

DNA methylation patterns: an additional level of information?

1991 • 49 citations

Antimycotic sterol biosynthesis inhibitors

1986 • 32 citations