Complete eradication of hepatocellular carcinomas by combined vasostatin gene therapy and B7H3-mediated immunotherapy

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1994 • 3,367 citations

B7-H3: A costimulatory molecule for T cell activation and IFN-γ production

2001 • 916 citations

Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial

2000 • 848 citations

Hepatocellular carcinoma: Diagnosis and treatment

2002 • 590 citations

The B7 family member B7-H3 preferentially down-regulates T helper type 1–mediated immune responses

2003 • 516 citations

Hepatocellular carcinoma

1999 • 453 citations

During angiogenesis, vascular endothelial growth factor regulate natural killer cell adhesion to tumor endothelium

1996 • 449 citations

Murine B7-H3 Is a Negative Regulator of T Cells

2004 • 332 citations

Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expression.

2003 • 267 citations

Polyvinyl derivatives as novel interactive polymers for controlled gene delivery to muscle.

1996 • 222 citations

Calreticulin and Calreticulin Fragments Are Endothelial Cell Inhibitors That Suppress Tumor Growth

1999 • 182 citations

B7-H3 Enhances Tumor Immunity In Vivo by Costimulating Rapid Clonal Expansion of Antigen-Specific CD8+ Cytolytic T Cells

2004 • 177 citations

Gene transfer of antisense hypoxia inducible factor-1 α enhances the therapeutic efficacy of cancer immunotherapy

2001 • 144 citations

Continuous administration of angiostatin inhibits accelerated growth of colorectal liver metastases after partial hepatectomy.

2000 • 141 citations

Mouse B7-H3 induces antitumor immunity

2003 • 128 citations

Arsenic Stimulates Angiogenesis and Tumorigenesis In Vivo

2003 • 117 citations

Opposing effects of arsenic trioxide on hepatocellular carcinomas in mice

2006 • 112 citations

NK Cell Triggering by the Human Costimulatory Molecules CD80 and CD86

1999 • 102 citations

Arsenic trioxide therapy for relapsed or refractory Japanese patients with acute promyelocytic leukemia: need for careful electrocardiogram monitoring

2002 • 98 citations

Modelling approaches for angiogenesis

2004 • 89 citations

Effective targeting of tumor vasculature by the angiogenesis inhibitors vasostatin and interleukin-12

2000 • 84 citations

Immune-inflammatory mechanisms in IFNγ-mediated anti-tumor activity

2000 • 75 citations

A gene therapy for cancer based on the angiogenesis inhibitor, vasostatin

2002 • 71 citations

Laminin binding to the calreticulin fragment vasostatin regulates endothelial cell function

2002 • 63 citations

Proposal of invasiveness score to predict recurrence and survival after curative hepatic resection for hepatocellular carcinoma

1997 • 63 citations

The Angiogenesis Inhibitor Vasostatin does not Impair Wound Healing at Tumor-Inhibiting Doses

2001 • 62 citations

Arsenic trioxide synergizes with B7H3‐mediated immunotherapy to eradicate hepatocellular carcinomas

2005 • 54 citations

Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci.

2001 • 50 citations

The promise of anti-angiogenic cancer therapy

2000 • 50 citations

Angiogenic Profile of Breast Carcinoma Determines Leukocyte Infiltration

2004 • 49 citations

Combined endostatin/sFlt-1 antiangiogenic gene therapy is highly effective in a rat model of HCC

2005 • 46 citations

Antiangiogenic gene therapy for hepatocellular carcinoma using angiostatin gene

2003 • 43 citations

Anti-tumor activities of the angiogenesis inhibitors interferon-inducible protein-10 and the calreticulin fragment vasostatin

2002 • 37 citations

Angiostatin enhances B7.1-mediated cancer immunotherapy independently of effects on vascular endothelial growth factor expression

2001 • 35 citations

Combination of Interleukin 12 and Interferon α Gene Therapy Induces a Synergistic Antitumor Response against Colon and Renal Cell Carcinoma

2000 • 35 citations

Overexpression of von Hippel-Lindau tumor suppressor protein and antisense HIF-1α eradicates gliomas

2005 • 33 citations

Treatment of pancreatic carcinoma by adenoviral mediated gene transfer of vasostatin in mice

2005 • 17 citations

Angiogenesis Inhibitor TNP-470 Can Suppress Hepatocellular Carcinoma Growth Without Retarding Liver Regeneration After Partial Hepatectomy

2004 • 17 citations

Anti-angiogenic therapy subsequent to adeno-associated-virus-mediated immunotherapy eradicates lymphomas that disseminate to the liver

2004 • 17 citations

Combination of vasostatin gene therapy with cyclophosphamide inhibits growth of B16(F10) melanoma tumours.

2005 • 15 citations

Fusogenic activity of vesicular stomatitis virus glycoprotein plasmid in tumors as an enhancer of IL-12 gene therapy

2001 • 12 citations