Effect of Troglitazone on the Pharmacokinetics of an Oral Contraceptive Agent

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1994 • 2,716 citations

Metformin

1996 • 1,637 citations

The Human Hepatic Cytochromes P450 Involved in Drug Metabolism

1992 • 932 citations

Efficacy and Metabolic Effects of Metformin and Troglitazone in Type II Diabetes Mellitus

1998 • 798 citations

Characterization of New Oral Antidiabetic Agent CS-045: Studies in KK and ob/ob Mice and Zucker Fatty Rats

1988 • 459 citations

Metabolic Effects of New Oral Hypoglycemic Agent CS-045 in NIDDM Subjects

1992 • 423 citations

Effect of Troglitazone in Insulin-Treated Patients with Type II Diabetes Mellitus

1998 • 337 citations

The increase in urinary excretion of 6 beta‐hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction.

1989 • 334 citations

Metabolic Effects of Troglitazone Monotherapy in Type 2 Diabetes Mellitus

1998 • 293 citations

Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients

1996 • 239 citations

Oxidation of 17 alpha-ethynylestradiol by human liver cytochrome P-450.

1988 • 229 citations

Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation.

1993 • 225 citations

Effect of New Oral Antidiabetic Agent CS-045 on Glucose Tolerance and Insulin Secretion in Patients with NIDDM

1991 • 197 citations

The interaction of phenytoin and carbamazepine with combined oral contraceptive steroids.

1990 • 178 citations

Clinical Pharmacokinetics of Oral Contraceptive Steroids

1983 • 173 citations

In vitro studies on the action of CS-045, a new antidiabetic agent

1990 • 165 citations

The interaction of phenobarbital and other anticonvulsants with oral contraceptive steroid therapy

1980 • 131 citations

Pharmacokinetics and biotransformation studies of terfenadine in man.

1982 • 125 citations

Metabolism of levonorgestrel, norethindrone, and structurally related contraceptive steroids

1990 • 121 citations

Clinical Pharmacokinetics of Troglitazone

1999 • 113 citations

Sulfonylurea Drugs: Mechanism of Antidiabetic Action and Therapeutic Usefulness

1978 • 90 citations

The effect of rifampicin oh the pharmacokinetics of ethynylestradiol in women

1980 • 89 citations

Prediction of the human pharmacokinetics of troglitazone, a new and extensively metabolized antidiabetic agent, after oral administration, with an animal scale-up approach.

1996 • 86 citations

Metabolism of terfenadine associated with CYP3A(4) activity in human hepatic microsomes.

1995 • 83 citations

The effect of rifampicin on norethisterone pharmacokinetics

1979 • 82 citations

Kinetics of norethindrone in women; II. Single‐dose kinetics

1978 • 76 citations

Intestinal metabolism of ethinyloestradiol and paracetamol in vitro: studies using Ussing chambers.

1987 • 67 citations

Studies on the Metabolism of Ethynylestradiolin vitroandin vivo: The Significance of 2-Hydroxylation and the Formation of Polar Products

1973 • 65 citations

The pharmacokinetics of ethynylestradiol in the presence and absence of gestodene and desogestrel

1991 • 56 citations

Group comparison of serum ethinyl estradiol, SHBG and CBG levels in 83 women using two low-dose combination oral contraceptives for three months

1991 • 54 citations

Kinetics of norethindrone in women; I. Radioimmunoassay and concentrations during multiple dosing

1978 • 45 citations

Lack of Effect of Type II Diabetes on the Pharmacokinetics of Troglitazone in a Multiple‐Dose Study

1997 • 43 citations

Hormonal contraceptives and plasma sex hormone binding globulin

1975 • 36 citations

Effect of troglitazone on urinary excretion of 6beta-hydroxycortisol.

1998 • 33 citations

Accumulation of norethindrone and individual metabolites in human plasma during short- and long-term administration of a contraceptive dosage

1979 • 31 citations

Effect of Troglitazone on Urinary Excretion of 6β‐Hydroxycortisol

1998 • 29 citations

Meta‐Analysis of Steady‐State Pharmacokinetics of Troglitazone and Its Metabolites

1997 • 23 citations

Pharmacokinetics and protein binding of gestodene under treatment with a low-dose combination oral contraceptive for three months.

1992 • 15 citations

Cited By (0)

Loading...