Flurothyl status epilepticus in developing rats: behavioral, electrographic histological and electrophysiological studies

Clinics in Developmental Medicine

2013 • 1,161 citations

Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats

1985 • 1,101 citations

Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuropathological study

1983 • 1,082 citations

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

1978 • 745 citations

Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: The “dormant basket cell” hypothesis and its possible relevance to temporal lobe epilepsy

1991 • 706 citations

Kainic acid induced limbic seizures: metabolic, behavioral, electroencephalographic and neuropathological correlates

1981 • 683 citations

Predictors of Epilepsy in Children Who Have Experienced Febrile Seizures

1976 • 661 citations

Mossy fiber synaptic reorganization induced by kindling: time course of development, progression, and permanence

1991 • 539 citations

Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures

1994 • 461 citations

Magnetic resonance imaging evidence of hippocampal injury after prolonged focal febrile convulsions

1998 • 459 citations

Kainic-acid-induced seizures: A developmental study

1984 • 369 citations

Maturation of kainic acid seizure-brain damage syndrome in the rat. II. Histopathological sequelae

1984 • 355 citations

Hippocampal neuron loss in temporal lobe epilepsy: Correlation with early childhood convulsions

1987 • 325 citations

Status epilepticus in well–oxygenated rats causes neuronal necrosis

1985 • 312 citations

The susceptibility of rats to pilocarpine-induced seizures is age-dependent

1987 • 305 citations

Status epilepticus: epidemiologic considerations.

1990 • 298 citations

Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers

1992 • 279 citations

Atrophy of mesial structures in patients with temporal lobe epilepsy: Cause or consequence of repeated seizures?

1993 • 271 citations

Activation of N-methyl-D-aspartate receptors parallels changes in cellular and synaptic properties of dentate gyrus granule cells after kindling

1988 • 261 citations

Resistance of the immature hippocampus to seizure-induced synaptic reorganization

1991 • 245 citations

A Reliable and Sensitive Method to Localize Terminal Degeneration and Lysosomes in the Central Nervous System

1980 • 240 citations

Hippocampal malformation as a cause of familial febrile convulsions and subsequent hippocampal sclerosis

1998 • 239 citations

Increased seizure susceptibility of the immature brain

1983 • 226 citations

Magnetic resonance imaging in childhood intractable partial epilepsies

1993 • 212 citations

Biological Factors in Temporal Lobe Epilepsy

1967 • 210 citations

Abnormal neuronal excitability in hippocampal slices from kindled rats

1985 • 206 citations

Temporal Lobectomy in Early Childhood

1992 • 205 citations

Outcome of childhood status epilepticus and lengthy febrile convulsions: findings of national cohort study.

1993 • 193 citations

In Whom Does Status Epilepticus Occur: Age‐Related Differences in Children

1997 • 192 citations

Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats

1995 • 188 citations

Age at onset of seizures in young children

1984 • 164 citations

Developmental aspects of the pilocarpine model of epilepsy

1996 • 161 citations

Relationship of hippocampal sclerosis to duration and age of onset of epilepsy, and childhood febrile seizures in temporal lobectomy patients

1996 • 159 citations

Epilepsy surgery outcome

1997 • 154 citations

[25] Use of excitatory amino acids to make axon-sparing lesions of hypothalamus

1983 • 150 citations

Evidence that repetitive seizures in the hippocampus cause a lasting reduction of GABAergic inhibition

1989 • 143 citations

Neuronal Migration Disorders Increase Susceptibility to Hyperthermia‐Induced Seizures in Developing Rats

1996 • 141 citations

Temporal Lobe Epilepsy in Early Childhood

1993 • 141 citations

Effects of neonatal status epilepticus on rat brain development

1976 • 139 citations

The development and decay of kindling-induced increases in paired-pulse depression in the dentate gyrus

1987 • 134 citations

Ontogenic study of lithium-pilocarpine-induced status epilepticus in rats

1992 • 131 citations

Febrile Status Epilepticus

1990 • 126 citations

Nerve Growth Factor Accelerates Seizure Development, Enhances Mossy Fiber Sprouting, and Attenuates Seizure-Induced Decreases in Neuronal Density in the Kindling Model of Epilepsy

1997 • 125 citations

Alterations of inhibitory processes in the dentate gyrus following kindling-induced epilepsy

1985 • 125 citations

Effects of kainic acid on seizure susceptibility in the developing brain

1988 • 121 citations

Childhood generalized and mesial temporal epilepsies demonstrate different amounts and patterns of hippocampal neuron loss and mossy fibre synaptic reorganization

1996 • 117 citations

The effects of kindling on GABA-mediated inhibition in the dentate gyrus of the rat. II. Receptor binding

1983 • 116 citations

Status Epilepticus in Children: Etiology, Clinical Features, and Outcome

1988 • 114 citations

Serum neuron-specific enolase is a marker for neuronal damage following status epilepticus in the rat

1997 • 111 citations

Recurrent status epilepticus in children

1992 • 107 citations

Activation of the dentate gyrus by pentylenetetrazol evoked seizures induces mossy fiber synaptic reorganization

1992 • 103 citations

Kainic Acid-Induced Seizures Enhance Dentate Gyrus Inhibition by Downregulation of GABA_BReceptors

1996 • 99 citations

Hippocampal sclerosis studied in identical twins

1998 • 88 citations

Pathology of temporal lobe foci.

1975 • 86 citations

Experimental seizure-threshold testing with fluorthyl.

1969 • 81 citations

The model of pentylenetetrazol-induced status epilepticus in the immature rat: short- and long-term effects

1996 • 79 citations

Peptide-induced infant status epilepticus causes neuronal death and synaptic reorganization

1995 • 76 citations

Alteration in dentate neuronal activities associated with perforant path kindling

1987 • 74 citations

Injections of picrotoxin and bicuculline into the amygdaloid complex of the rat: An electroencephalographic, behavioural and morphological analysis

1985 • 73 citations

Changes in inhibitory processes in the hippocampus following recurrent seizures induced by systemic administration of kainic acid

1991 • 73 citations

Evidence for a chronic loss of inhibition in the hippocampus after kindling: electrophysiological studies

1989 • 71 citations

Infantile status epilepticus and future seizure susceptibility in the rat

1984 • 71 citations

Evidence of Enhanced Kindliig and Hippocampal Neuronal Injury in Immature Rats with Neuronal Migration Disorders

1998 • 68 citations

Age-related differences in seizure susceptibility to flurothyl

1988 • 67 citations

An immature mossy fiber innervation of hilar neurons may explain their resistance to kainate-induced cell death in 15-day-old rats

1994 • 66 citations

Transplacentally induced neuronal migration disorders: An animal model for the study of the epilepsies

1998 • 59 citations

Effects of hippocampal kindling on paired-pulse response in CA1 in vitro

1991 • 59 citations

Bicuculline induced seizures in infant rats: ontogeny of behavioral and electrocortical phenomena

1990 • 58 citations

Developmental Regulation of Glutamate and GABA<sub>A</sub> Receptor Gene Expression in Rat Hippocampus following Kainate-Induced Status epilepticus

1997 • 57 citations

MEASUREMENT OF BRAIN EXCITABILITY BY USE OF HEXAFLUORODIETHYL ETHER (INDOKLON)

1960 • 57 citations

Effect of Status Epilepticus on Hypoxic-Ischemic Brain Damage in the Immature Rat

1995 • 56 citations

Prognosis of Childhood Epilepsy in Newly Referred Patients

1996 • 54 citations

Chronic epilepsy with damage restricted to the hippocampus: possible mechanisms

1996 • 49 citations

Status epilepticus results in reversible neuronal injury in infant rat hippocampus: novel use of a marker

1994 • 48 citations

Repetitive seizures cause an increase in paired-pulse inhibition in the dentate gyrus

1989 • 45 citations

Microinjections of the γ-aminobutyrate antagonist, bicuculline methiodide, into the caudate-putamen prevent amygdala-kindled seizures in rats

1987 • 41 citations

Inhibition of the rate of GABA synthesis in regions of rat brain following a convulsion

1987 • 36 citations

Kainic Acid Seizures and Neuronal Cell Death: Insights from Studies of Selective Lesions and Drugs

1986 • 30 citations

Brain protein metabolism in epilepsy.

1986 • 30 citations

The pathological substrate of temporal lobe epilepsy.

1970 • 26 citations

Inhibition of GABA release from slices prepared from several brain regions of rats at various times following a convulsion

1987 • 25 citations

The action of volatile anesthetics and convulsants on synaptic transmission: a unified concept.

1977 • 23 citations

Convulsant Activity of Nonanesthetic Gas Combinations

1997 • 22 citations

Neuropathological changes during generalized seizures in newborn monkeys

1992 • 14 citations

A STUDY OF THE CENTRAL ACTION OF FLUROTHYL AND METHOXYFLURANE

1971 • 7 citations