A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange.

Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ

1979 • 2,166 citations

Intracellular pH transients in squid giant axons caused by CO2, NH3, and metabolic inhibitors.

1976 • 913 citations

CRYSTAL STRUCTURES OF THE HELIX-LOOP-HELIX CALCIUM-BINDING PROTEINS

1989 • 855 citations

Molecular cloning, primary structure, and expression of the human growth factor-activatable antiporter

1989 • 774 citations

Detection of Calcium Binding Proteins by 45Ca Autoradiography on Nitrocellulose Membrane after Sodium Dodecyl Sulfate Gel Electrophoresis1

1984 • 772 citations

Molecular and Structural Basis of Target Recognition by Calmodulin

1995 • 752 citations

Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation

1989 • 749 citations

A role for Rho in Ras transformation.

1995 • 538 citations

Human placental HLA-G expression is restricted to differentiated cytotrophoblasts.

1995 • 479 citations

Growth Factors Induce Phosphorylation of the Na ⁺ /H ⁺ Antiporter, a Glycoprotein of 110 kD

1990 • 452 citations

Hormonal regulation, pharmacology, and membrane sorting of vertebrate Na+/H+ exchanger isoforms

1995 • 394 citations

Interaction cloning: identification of a helix-loop-helix zipper protein that interacts with c-Fos

1992 • 348 citations

The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor.

1992 • 324 citations

The Na+/H+ exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins. Identification and characterization of calmodulin-binding sites.

1994 • 305 citations

The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing".

1992 • 291 citations

Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation.

1994 • 257 citations

Mutation of calmodulin-binding site renders the Na+/H+ exchanger (NHE1) highly H(+)-sensitive and Ca2+ regulation-defective.

1994 • 247 citations

Activation of the Na+/H+ antiporter during cell volume regulation. Evidence for a phosphorylation-independent mechanism.

1992 • 223 citations

A WD-domain protein that is associated with and phosphorylated by the type II TGF-β receptor

1995 • 196 citations

Alpha-thrombin, epidermal growth factor, and okadaic acid activate the Na+/H+ exchanger, NHE-1, by phosphorylating a set of common sites.

1991 • 189 citations

G alpha 13 stimulates Na-H exchange.

1994 • 175 citations

Gα13 Stimulates Na+-H+ Exchange through Distinct Cdc42-dependent and RhoA-dependent Pathways

1996 • 171 citations

Growth factor activation and “H(+)-sensing” of the Na+/H+ exchanger isoform 1 (NHE1). Evidence for an additional mechanism not requiring direct phosphorylation.

1994 • 166 citations

Subcellular localization and trafficking of the GLUT4 glucose transporter isoform in insulin‐responsive cells

1994 • 133 citations

Hypertensive sodium-proton exchanger phenotype persists in immortalized lymphoblasts from essential hypertensive patients. A cell culture model for human hypertension.

1993 • 121 citations

Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions.

1990 • 119 citations

Protein kinase C-dependent and -independent activation of Na+/H+ exchanger by G alpha 12 class of G proteins.

1994 • 109 citations

Microinjection of ras p21 Induces a Rapid Rise in Intracellular pH

1987 • 100 citations

Cytokines and HIV envelope glycoprotein gp120 stimulate Na+/H+ exchange in astrocytes.

1994 • 91 citations

Long-term expression of c-H-ras stimulates Na-H and Na(+)-dependent Cl-HCO3 exchange in NIH-3T3 fibroblasts.

1994 • 85 citations

Gα12 Differentially Regulates Na+-H+ Exchanger Isoforms

1996 • 81 citations

A Novel Ca2+-binding Protein, p22, Is Required for Constitutive Membrane Traffic

1996 • 79 citations

Responsiveness of mutants of NHE1 isoform of Na+/H+ antiport to osmotic stress

1995 • 79 citations

Differential expression of calmodulin-binding proteins in B, T lymphocytes and thymocytes

1987 • 70 citations

Na⁺/H⁺ antiporter gene expression increases during retinoic acid‐induced granulocytic differentiation of HL60 cells

1992 • 52 citations

G alpha q and G alpha 13 regulate NHE-1 and intracellular calcium in epithelial cells

1995 • 51 citations

Ha-ras activates the Na+/H+ antiporter by a protein kinase C-independent mechanism

1989 • 46 citations

Role of cytoplasmic domain of the Na+/H+ exchanger in hormonal activation.

1993 • 41 citations

Guanine nucleotides regulate beta-adrenergic activation of Na-H exchange independently of receptor coupling to Gs.

1992 • 37 citations

Hypertrophy and hyperplasia cause differing effects on vascular smooth muscle cell Na+/H+ exchange and intracellular pH.

1990 • 36 citations

Mechanisms of receptor-mediated regulation of Na-H exchange

1991 • 19 citations