Hypertensive sodium-proton exchanger phenotype persists in immortalized lymphoblasts from essential hypertensive patients. A cell culture model for human hypertension.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Intracellular pH.

1981 • 2,440 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation

1989 • 749 citations

Activation of the Na+/H+ antiporter during cell volume regulation. Evidence for a phosphorylation-independent mechanism.

1992 • 223 citations

Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2)

1993 • 215 citations

Spontaneously hypertensive rat vascular smooth muscle cells in culture exhibit increased growth and Na+/H+ exchange.

1989 • 190 citations

Alpha-thrombin, epidermal growth factor, and okadaic acid activate the Na+/H+ exchanger, NHE-1, by phosphorylating a set of common sites.

1991 • 189 citations

Membrane sodium-proton exchange and primary hypertension.

1993 • 170 citations

Exclusion of the Na(+)-H+ antiporter as a candidate gene in human essential hypertension.

1991 • 139 citations

Okadaic acid, a phosphatase inhibitor, induces activation and phosphorylation of the Na+/H+ antiport

1991 • 112 citations

Kinetic abnormalities of the red blood cell sodium-proton exchange in hypertensive patients.

1991 • 96 citations

Structure function of the growth factor-activatable Na+/H+ exchanger (NHE1)

1992 • 92 citations

Abnormal structure and function of isolated subcutaneous resistance vessels from essential hypertensive patients despite antihypertensive treatment.

1989 • 76 citations

Sodium-lithium countertransport and cardiorenal abnormalities in essential hypertension.

1991 • 61 citations

Differential regulation of Na+/H+ antiporter gene expression in vascular smooth muscle cells by hypertrophic and hyperplastic stimuli.

1990 • 58 citations

Platelet Na(+)-H+ exchanger activity in normotensive and hypertensive subjects: effect of enalapril therapy upon antiport activity.

1992 • 53 citations

Role of cytoplasmic domain of the Na+/H+ exchanger in hormonal activation.

1993 • 41 citations

Cytosolic pH sensitivity of an expressed human NHE-1 Na(+)-H+ exchanger

1993 • 32 citations

Molecular biology and hormonal regulation of vertebrate Na+/H+ exchanger isoforms.

1993 • 28 citations

Blood pressure and cardiac structure in children with a parental history of hypertension

1992 • 26 citations

Kinetics of the Human Lymphocyte Na+-H+ Exchanger

1990 • 19 citations

Vascular smooth muscle cells from the Milan hypertensive rat exhibit decreased functional angiotensin II receptors.

1990 • 18 citations

Phosphorylation of Na(+)-H+ antiporter is not stimulated by phorbol ester and acidification in granulocytic HL-60 cells

1993 • 18 citations

Detection of Na⁺/H⁺ exchanger mRNA in human neutrophils and lymphocytes using the polymerase chain reaction

1991 • 9 citations

Structure and Function of Resistance Vessels in Hypertension

1991 • 1 citations